Journal of Functional Biomaterials, Volume 16, Issue 2

Resonance frequency analysis (RFA) has been used as a diagnostic method to measure implant stability at all stages of healing. In addition to evaluating the status of the peri-implant marginal bone, it can also indicate the most appropriate time to l...

This study introduces innovative varnishes incorporating natural bioactive compounds to inhibit the formation of oral dual biofilms, a critical contributor to dental caries and other oral diseases. The purpose of this study was to evaluate the effect...

Hydrogel network structures play a crucial role in determining mechanical properties and have broad applications in biomedical and industrial fields. Therefore, their rational design is essential. Herein, we developed a Schiff base-crosslinked hydrog...

Objectives: The objectives of this study were to investigate in vitro BPA release from two common fiberglass fixed lingual canine-to-canine retainers and to compare these amounts with those released from a conventional multistranded stainless-steel o...

The aim of the present study was to test the sequential and simultaneous release of rhBMP2 and rhVEGF165 from poly-l-lysine-heparin (PLL-Hep) poly-electrolyte multilayer (PEM) coating on titanium surfaces for their ability to enhance peri-implant bon...

Bacterial growth on implant surfaces poses a significant obstacle to the long-term success of dental and orthopedic implants. There is a need for implants that promote osseointegration while at the same time decreasing or preventing bacterial growth....

The aim of this study was to analyze the marginal bone loss and survival of implants in the augmented sinus area via the lateral window approach. The effect of sinus membrane perforation as well as splinting of the upper structure was analyzed. Two h...

The extraction of deeply impacted lower third molars is a common yet challenging surgical procedure associated with complications such as mandibular fractures, pain, and swelling. This study evaluated the effectiveness of customized 3D-printed titani...

The nonunion and delayed union of bones are common challenges in orthopedic surgery, even when bone alignment is correct and sufficient mechanical stability is provided. To address this, artificial bone grafts are often applied to fracture gaps or de...

Objective: Osteogenic differentiation is a complex process, and its analysis requires several biomarkers. Allied with this, there are no standardized bioassays to monitor the activity of simvastatin in osteogenesis in vitro. Therefore, identifying th...

Three-dimensional (3D)-printing technology is revolutionizing orthopedic oncology by providing precise, customized solutions for complex bone defects following tumor resection. Traditional modular endoprostheses are prone to complications such as fre...

Zirconia restorations are widely used in dentistry due to their high esthetic expectations and physical durability. However, zirconia’s opaque white color can compromise esthetics. Therefore, zirconia is often veneered with porcelain, but fract...

Background: This descriptive study aimed to assess the survival rates and outcomes of dental implants in one of the four national HMOs in Israel. Data are provided for the period from 1 January 2014 to 31 December 2022. Materials and Methods: This re...

Bone substitutes are commonly used in bone regeneration, and their functionalization with bioactive molecules can significantly enhance bone regeneration by directly influencing bone cells. This study aimed to evaluate the potential of raloxifene-fun...

There is currently a demand for anti-adhesive materials that are capable of preventing the formation of intra-abdominal adhesions. In this study, electrospun poly(lactide-co-glycolide) scaffolds were dip-coated in aqueous solutions of polyvinyl alcoh...

Volumetric muscle loss (VML) results in the impediment of skeletal muscle function. Tissue engineering scaffolds have been widely developed and used in skeletal muscle regeneration. However, scaffold implantation causes an immune response that endoge...

Tendon injuries account for 45% of musculoskeletal injuries. However, research on the occurrence and pathogenesis of tendinopathy is insufficient, and there is still much debate regarding treatment methods. It is important to understand the molecular...

Background: Dental implantology has evolved significantly since the introduction of additive manufacturing, which allows for the reproduction of natural bone’s porous architecture to improve bone tissue compatibility and address stress distribu...

Laser powder bed fusion (LPBF) has emerged as a transformative additive manufacturing technique for fabricating architected cellular metallic structures, offering tailored properties for diverse biomedical applications. These structures are particula...

In recent years, factors such as the postponement of childbearing and the relaxation of the childbearing policy have led to an increase in the proportion of cesarean sections and other intrauterine surgeries among pregnant women, further increasing t...

Fibrosis after full-thickness wound healing—especially after severe burn wounds—remains a clinically relevant problem. Biomaterials that mimic the lost dermal extracellular matrix have shown promise but cannot completely prevent scar form...

Peripheral nerve injuries affect 13–23 per 100,000 people annually in the U.S. and often result in motor and sensory deficits. Microsurgical suture repair (SR) is the standard treatment but is technically challenging and associated with complic...

In restorative dentistry, there are no standardized in vitro accelerated aging methods to evaluate the long-term stability of dental composites. Current research aimed at extending the clinical success of restorations emphasizes the need for post-agi...

Introduction: Vascular graft infections (VGEIs) are rare but severe complications in vascular surgery. The choice of reconstruction material following graft removal is critical, particularly for infection prevention. This study evaluates the use of N...

Collagen and its peptides exhibit remarkable antioxidant activity, superior biocompatibility, and water solubility, making them a significant research focus in skin care. Hence, the recombinant humanized collagen types I, III, and XVII complexed with...

The present review provides an up-to-date overview of chairside CAD/CAM materials used in restorative dentistry, focusing on their classification, properties, and clinical applications. If CAD/CAM technology was only an aspiration in the past, a high...

Chitosan is a positively charged natural polymer with several properties conducive to wound-healing applications, such as biodegradability, structural integrity, hydrophilicity, adhesiveness to tissue, and bacteriostatic potential. Along with other m...

The study is a metallographic analysis of commercial bone plates used for stabilizing long bones. The plates examined were delivered to the hospital in different years, and the course of treatment of patients with similar goniometric and anthropometr...

Photoactive hydrogels facilitate light-triggered photochemical processes, positioning them as innovative solutions in biomedical applications, especially in antimicrobial photodynamic therapy. This study presents a novel methylene blue-based photoact...

The preservation of interfacial integrity in esthetic dental restorations remains a critical challenge, with hybrid layer degradation being a primary factor in restoration failure. This degradation is driven by a combination of host-derived enzymatic...

Nanoparticle-based X-ray radiosensitization strategies have garnered significant attention in recent years. However, the underlying mechanisms of radiosensitization remain incompletely understood. In this work, we explore the influence of the K-edge...

Background: Understanding microbial colonization on different membranes is critical for guided bone regeneration procedures such as socket preservation, as biofilm formation may affect healing and clinical outcomes. This randomized controlled clinica...

This study aimed to comparatively evaluate the biomechanical behaviors of three types of dental implant restorations: a screw-and-cement-retained prosthetic system (SCRP); a cementless screw-retained prosthetic system (SRP); and a novel screwless hoo...

Recent advancements in biomimetic dentistry have introduced innovative materials designed to better simulate natural dentin. One such material is Ribbond^®, long polyethylene fiber. It is particularly effective in absorbing and redistributing mast...

The performance of an orthopedic procedure depends on several tandem functionalities. Such characteristics include materials’ surface properties and subsequent responses. Implant surfaces are typically roughened; this roughness can further be o...