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Recent Advances in Bone Graft Materials
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Recent Advances in Bone Graft Materials

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials and Devices for Healthcare Applications".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 2682

Special Issue Editors

Dr. Motohiro Munakata

E-Mail Website
Guest Editor
Department of Implant Dentistry, School of Dentistry, Showa University, 2-1-1 Kitasenzoku Ota-ku, Tokyo 1458515, Japan
Interests: biomaterials; graft material; dental implant; bone augmentation
Special Issues, Collections and Topics in MDPI journals
Dr. Yu Kataoka

E-Mail Website
Guest Editor
Department of Biomaterials and Engineering, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan
Interests: biomaterials; graft material; titanium; digital dentistry
Dr. Daisuke Sato

E-Mail Website
Guest Editor
Department of Implant Dentistry, Showa University School of Dentistry, Tokyo 145-8515, Japan
Interests: implant dentistry; prosthodontics; oral surgery; gerodontics; dental materials

Special Issue Information

Dear Colleagues,

In the past, autologous bone was the only bone grafting material with osteoconductive, osteoinductive, and osteogenic properties, but various bone grafting materials have now been developed and are being applied clinically.

This Special Issue will gather research on bone regeneration, focusing on the clinical application of novel and various bone grafting materials and the comparison of bone grafting materials in bone regeneration. Basic and clinical research, including animal studies, and review articles are welcome.

Dr. Motohiro Munakata
Dr. Yu Kataoka
Dr. Daisuke Sato
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dental implant
  • graft material
  • bone augmentation
  • bone regeneration

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

18 pages, 3793 KB  
Article
Three-Dimensional Objective Evaluation of the Changes in the Alveolar Ridge Before and After Horizontal Bone Augmentation Along with Implant Placement Using Intraoral Digital Scanning: A Prospective Study
by Naoki Kitamura, Kikue Yamaguchi, Kaiya Himi, Kota Ishii and Motohiro Munakata
J. Funct. Biomater. 2025, 16(9), 312; https://doi.org/10.3390/jfb16090312 - 28 Aug 2025
Viewed by 625
Abstract
Implant treatment in the aesthetic regions of the jaw often requires hard and soft tissue augmentation to ensure optimal prosthetic outcomes. Radiological evaluation with cone-beam computed tomography (CBCT) and visual inspection of intraoral photographs are effective for assessing hard tissues but are limited [...] Read more.
Implant treatment in the aesthetic regions of the jaw often requires hard and soft tissue augmentation to ensure optimal prosthetic outcomes. Radiological evaluation with cone-beam computed tomography (CBCT) and visual inspection of intraoral photographs are effective for assessing hard tissues but are limited in evaluating soft tissues. This study aimed to objectively evaluate volumetric and dimensional changes of the alveolar ridge, including both hard and soft tissues, following simultaneous horizontal bone augmentation and implant placement using intraoral digital scanning. Intraoral digital scans were obtained at baseline (T0) and at 2 (T1), 6 (T2), and 12 weeks (T3) post-surgery. Scans were superimposed using dedicated imaging software to measure volumetric and cross-sectional changes. Volumetric gain was significant at T1 but decreased significantly from T1 to T2 (p = 0.0006) and from T1 to T3 (p = 0.0002). Cross-sectional analysis showed significant increases in ridge width at T1 at all measured levels, accompanied by a significant vertical decrease at the alveolar crest from T1 to T2 (p = 0.0056) and T3 (p = 0.0106).These findings indicate that horizontal augmentation provides initial volumetric gain but is followed by substantial reduction at the crest, suggesting that rigid fixation may enhance stability; however, controlled clinical trials are required. Full article
(This article belongs to the Special Issue Recent Advances in Bone Graft Materials)
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13 pages, 1644 KB  
Article
Dental Implant Rehabilitation of Posterior Maxillary Edentulism via Sinus Augmentation Using the Lateral Window Technique: A Retrospective Analysis of 289 Implants Followed Up for 15 Years
by Alper Sağlanmak, Volkan Arısan, Cüneyt Karabuda and Hakan Özyuvacı
J. Funct. Biomater. 2025, 16(2), 65; https://doi.org/10.3390/jfb16020065 - 13 Feb 2025
Cited by 1 | Viewed by 1261
Abstract
The aim of this study was to analyze the marginal bone loss and survival of implants in the augmented sinus area via the lateral window approach. The effect of sinus membrane perforation as well as splinting of the upper structure was analyzed. Two [...] Read more.
The aim of this study was to analyze the marginal bone loss and survival of implants in the augmented sinus area via the lateral window approach. The effect of sinus membrane perforation as well as splinting of the upper structure was analyzed. Two hundred and eighty-nine implants were placed in the sinus areas augmented with xenografts and collagen membranes in 101 patients. Clinical and radiographic data were obtained during recall visits. The Marginal Bone Loss (MBL) and Cumulative Survival Rate (CSR) were evaluated. The mean follow-up period was 12.4 years (range: 12 to 182 months). During the follow-up period, 19 implants were lost, yielding a 92.93% survival rate. No significant models for any of the covariates were found in terms of implant survival (p = 0.08). Similarly, no significant differences were observed between intact and perforated sinuses (p = 0.41) or between splinted or single standing implants (p = 0.11). The overall MBL reached 1.80 ± 0.56 mm at 15 years, and no significant differences were detected between any particular years (p = 0.12). Dental implant rehabilitation of the posterior maxilla via sinus augmentation using the lateral window technique is safe, effective and provides a high long-term implant survival with minimal prosthetic complications. Full article
(This article belongs to the Special Issue Recent Advances in Bone Graft Materials)
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