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Journal of Functional Biomaterials, Volume 14, Issue 9

2023 September - 49 articles

Cover Story: Targeted therapy is the most suitable practical approach for drug administration using hydrogels, as they are the most effective "vehicles" for drug delivery without causing adverse side effects. Herein, three different recipes of multi-component hydrogels were simultaneously cross-linked and sterilized by e-beam at 25 kGy. The multi-component hydrogels were obtained from aqueous polymer mixtures in which different proportions of bovine collagen gel, sodium carboxymethylcellulose, poly(vinylpyrrolidone), chitosan, and poly(ethylene oxide) were used. The study showed the efficiency of manufacturing hydrogels by e-beam irradiation and demonstrated the developed structures' suitability to be used as targeted and controlled drug delivery platforms employing in vitro cell-based assays. View this paper
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Articles (49)

  • Article
  • Open Access
5 Citations
4,670 Views
13 Pages

21 September 2023

Dental ceramics are susceptible to slow, progressive crack growth after cyclic loading. The purpose of this study was to investigate the progressive patterns of cracks in two different types of CAD/CAM ceramic materials used with three different part...

  • Review
  • Open Access
12 Citations
5,684 Views
20 Pages

20 September 2023

The unique characteristics of stem cells, which include self-renewal and differentiation into specific cell types, have paved the way for the development of various biomedical applications such as stem cell therapy, disease modelling, and drug screen...

  • Article
  • Open Access
2 Citations
2,747 Views
23 Pages

Polyacrylate–Cholesterol Amphiphilic Derivative: Formulation Development and Scale-up for Health Care Applications

  • Marco Viola,
  • Claudia Migliorini,
  • Fabio Ziarelli,
  • Stéphane Viel,
  • Claudia Cencetti,
  • Daniel Di Risola,
  • Luciana Mosca,
  • Laura Masuelli,
  • Pietro Matricardi and
  • Chiara Di Meo

20 September 2023

The novel amphiphilic polyacrylate grafted with cholesterol moieties, PAAbCH, previously synthesized, was deeply characterized and investigated in the lab and on a pre-industrial scale. Solid-state NMR analysis confirmed the polymer structure, and se...

  • Opinion
  • Open Access
8 Citations
2,807 Views
12 Pages

Electrospun Scaffolds as Antimicrobial Herbal Extract Delivery Vehicles for Wound Healing

  • Caglar Ersanli,
  • Chrysoula (Chrysa) Voidarou,
  • Athina Tzora,
  • Konstantina Fotou,
  • Dimitrios I. Zeugolis and
  • Ioannis Skoufos

19 September 2023

Herbal extracts have been used in traditional remedies since the earliest myths. They have excellent antimicrobial, anti-inflammatory, and antioxidant activities owing to various bioactive components in their structure. However, due to their inabilit...

  • Review
  • Open Access
20 Citations
3,246 Views
27 Pages

19 September 2023

Biocompatible and biodegradable foams prepared using the high-pressure foaming technique have been widely investigated in recent decades as porous scaffolds for in vitro and in vivo tissue growth. In fact, the foaming process can operate at low tempe...

  • Article
  • Open Access
7 Citations
2,865 Views
15 Pages

19 September 2023

Scaffolds have been used to promote periodontal regeneration by providing control over the spacio-temporal healing of the periodontium (cementum, periodontal ligament (PDL) and alveolar bone). This study proposes to enhance the biofunctionality of a...

  • Feature Paper
  • Article
  • Open Access
6 Citations
2,725 Views
15 Pages

Adhesion and Activation of Blood Platelets on Laser-Structured Surfaces of Biomedical Metal Alloys

  • Marta Kamińska,
  • Aleksandra Jastrzębska,
  • Magdalena Walkowiak-Przybyło,
  • Marta Walczyńska,
  • Piotr Komorowski and
  • Bogdan Walkowiak

18 September 2023

The laser surface modification of metallic implants presents a promising alternative to other surface modification techniques. A total of four alloyed metallic biomaterials were used for this study: medical steel (AISI 316L), cobalt–chromium&nd...

  • Article
  • Open Access
12 Citations
3,408 Views
19 Pages

Radiolabeled Human Serum Albumin Nanoparticles Co-Loaded with Methotrexate and Decorated with Trastuzumab for Breast Cancer Diagnosis

  • Meliha Ekinci,
  • Luciana Magalhães Rebelo Alencar,
  • André Moreni Lopes,
  • Ralph Santos-Oliveira and
  • Derya İlem-Özdemir

18 September 2023

Breast cancer is a leading cause of cancer-related mortality among women worldwide, with millions of new cases diagnosed yearly. Addressing the burden of breast cancer mortality requires a comprehensive approach involving early detection, accurate di...

  • Article
  • Open Access
1 Citations
2,610 Views
11 Pages

Production of Feline Universal Erythrocytes with Methoxy Polyethylene Glycol

  • Hyung Kyu Kim,
  • Dan Bi Ahn,
  • Han Byeol Jang,
  • Jing Ma,
  • Juping Xing,
  • Joo Won Yoon,
  • Kyung Hee Lee,
  • Dong Min Lee,
  • Chang Hyun Kim and
  • Hee Young Kim

18 September 2023

Blood group mismatch in veterinary medicine is a significant problem in blood transfusion, sometimes leading to severe transfusion reactions and even patient death. Blood groups vary from species to species and there are three known blood groups in c...

  • Article
  • Open Access
3 Citations
3,047 Views
15 Pages

Biological Performance of Duplex PEO + CNT/PCL Coating on AZ31B Mg Alloy for Orthopedic and Dental Applications

  • Morteza Daavari,
  • Masoud Atapour,
  • Marta Mohedano,
  • Endzhe Matykina,
  • Raul Arrabal and
  • Dobrila Nesic

16 September 2023

To regulate the degradation rate and improve the surface biocompatibility of the AZ31B magnesium alloy, three different coating systems were produced via plasma electrolytic oxidation (PEO): simple PEO, PEO incorporating multi-walled carbon nanotubes...

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J. Funct. Biomater. - ISSN 2079-4983