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Journal of Clinical Medicine, Volume 7, Issue 9

September 2018 - 66 articles

Cover Story: Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal lining of the upper aerodigestive tract. Infection with high-risk human papillomaviruses (HPVs) has recently been implicated in the pathogenesis of HNSCCs. HPV-related HNSCCs and HPV-unrelated HNSCCs differ with respect to the molecular mechanisms underlying their oncogenic processes. To diagnose the HPV-related HNSCCs, various methods including P16 immunohistochemistry, FISH, and genetic analyses of the HPV gene from histopathological and liquid biopsy specimens have been employed. The cover image represents Mechanism of carcinogenesis by HPV. View this paper
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Articles (66)

  • Article
  • Open Access
9 Citations
4,134 Views
11 Pages

Estimation of Arterial Carbon Dioxide Based on End-Tidal Gas Pressure and Oxygen Saturation

  • Raisa Rentola,
  • Johanna Hästbacka,
  • Erkki Heinonen,
  • Per H. Rosenberg,
  • Tom Häggblom and
  • Markus B. Skrifvars

19 September 2018

Arterial blood gas (ABG) analysis is the traditional method for measuring the partial pressure of carbon dioxide. In mechanically ventilated patients a continuous noninvasive monitoring of carbon dioxide would obviously be attractive. In the current...

  • Review
  • Open Access
26 Citations
8,085 Views
36 Pages

Dystrophin Cardiomyopathies: Clinical Management, Molecular Pathogenesis and Evolution towards Precision Medicine

  • Domenico D’Amario,
  • Aoife Gowran,
  • Francesco Canonico,
  • Elisa Castiglioni,
  • Davide Rovina,
  • Rosaria Santoro,
  • Pietro Spinelli,
  • Rachele Adorisio,
  • Antonio Amodeo and
  • Gianluca Lorenzo Perrucci
  • + 3 authors

19 September 2018

Duchenne’s muscular dystrophy is an X-linked neuromuscular disease that manifests as muscle atrophy and cardiomyopathy in young boys. However, a considerable percentage of carrier females are often diagnosed with cardiomyopathy at an advanced s...

  • Article
  • Open Access
12 Citations
6,669 Views
10 Pages

Effects of Progressive Resistance Training on Post-Surgery Incontinence in Men with Prostate Cancer

  • Juhyun Park,
  • Dong Hyun Yoon,
  • Sangjun Yoo,
  • Sung Yong Cho,
  • Min Chul Cho,
  • Ga-Young Han,
  • Wook Song and
  • Hyeon Jeong

19 September 2018

We evaluated the efficacy of progressive resistance training of the pelvic floor muscle for post-prostatectomy incontinence. In this prospective study, 59 patients who underwent radical prostatectomy were evaluated preoperatively. Continence was sequ...

  • Review
  • Open Access
23 Citations
6,493 Views
16 Pages

New Molecular Technologies for Minimal Residual Disease Evaluation in B-Cell Lymphoid Malignancies

  • Irene Dogliotti,
  • Daniela Drandi,
  • Elisa Genuardi and
  • Simone Ferrero

18 September 2018

The clearance of malignant clonal cells significantly correlates with clinical outcomes in many hematologic malignancies. Accurate and high throughput tools for minimal residual disease (MRD) detection are needed to overcome some drawbacks of standar...

  • Article
  • Open Access
18 Citations
5,191 Views
12 Pages

The Role of Objectively Measured, Altered Physical Activity Patterns for Body Mass Index Change during Inpatient Treatment in Female Patients with Anorexia Nervosa

  • Celine S. Lehmann,
  • Tobias Hofmann,
  • Ulf Elbelt,
  • Matthias Rose,
  • Christoph U. Correll,
  • Andreas Stengel and
  • Verena Haas

18 September 2018

Increased physical activity (PA) affects outcomes in patients with anorexia nervosa (AN). To objectively assess PA patterns of hospitalized AN patients in comparison with healthy, outpatient controls (HC), and to analyze the effect of PA on Body Mass...

  • Article
  • Open Access
119 Citations
12,666 Views
8 Pages

The Effect of Gamification through a Virtual Reality on Preoperative Anxiety in Pediatric Patients Undergoing General Anesthesia: A Prospective, Randomized, and Controlled Trial

  • Jung-Hee Ryu,
  • Jin-Woo Park,
  • Francis Sahngun Nahm,
  • Young-Tae Jeon,
  • Ah-Young Oh,
  • Hak Jong Lee,
  • Jin-Hee Kim and
  • Sung-Hee Han

17 September 2018

The use of gamification in healthcare has been gaining popularity. This prospective, randomized, clinical trial was designed to evaluate whether gamification of the preoperative process—via virtual reality (VR) gaming that provides a vivid, imm...

  • Article
  • Open Access
9 Citations
4,033 Views
12 Pages

Pre-Procedural Statin Use Is Associated with Improved Long-Term Survival and Reduced Major Cardiovascular Events in Patients Undergoing Carotid Artery Stenting: A Retrospective Study

  • GianLuca Colussi,
  • Francesca Zuttion,
  • Bruno Bais,
  • Pierluigi Dolso,
  • Mariarosaria Valente,
  • Gian Luigi Gigli,
  • Daniele Gasparini,
  • Massimo Sponza,
  • Cristiana Catena and
  • Leonardo A. Sechi
  • + 1 author

17 September 2018

Carotid artery stenting (CAS) is a minimal invasive procedure used to resolve carotid occlusion that can be affected by peri-procedural complications. Statin use before CAS has shown to reduce peri-procedural risk and improve survival, though time-de...

  • Article
  • Open Access
15 Citations
5,777 Views
13 Pages

Effects of Statin Use in Advanced Chronic Kidney Disease Patients

  • Tao-Min Huang,
  • Vin-Cent Wu,
  • Yu-Feng Lin,
  • Jian-Jhong Wang,
  • Chih-Chung Shiao,
  • Likwang Chen,
  • Shih-Chieh Jeff Chueh,
  • Eric Chueh,
  • Shao-Yu Yang and
  • Tai-Shuan Lai
  • + 4 authors

17 September 2018

Although statin treatment is recommended for patients with chronic kidney disease (CKD) stages I–IV, its potential benefits have not been reported in advanced CKD patients. Non-diabetic patients with advanced CKD (pre-dialysis patients, estimated glo...

  • Article
  • Open Access
3 Citations
4,219 Views
12 Pages

Association of Wnt Inhibitors, Bone Mineral Density and Lifestyle Parameters in Women with Breast Cancer Treated with Anastrozole Therapy

  • Kristina Bojanić,
  • Ines Bilić Ćurčić,
  • Lucija Kuna,
  • Tomislav Kizivat,
  • Robert Smolic,
  • Nikola Raguž Lučić,
  • Kristina Kralik,
  • Vatroslav Šerić,
  • Gordana Ivanac and
  • Sandra Tucak-Zorić
  • + 2 authors

17 September 2018

Aim: To determine the levels of Wnt inhibitors in patients treated with aromatase inhibitors (AIs) prior to therapy and to investigate their association with bone mineral density (BMD) and lifestyle parameters. Methods: 137 breast cancer patients wer...

  • Article
  • Open Access
32 Citations
6,052 Views
15 Pages

In Vitro Study of Multi-Therapeutic Properties of Thymus bovei Benth. Essential Oil and Its Main Component for Promoting Their Use in Clinical Practice

  • Sherif T. S. Hassan,
  • Kateřina Berchová-Bímová,
  • Miroslava Šudomová,
  • Milan Malaník,
  • Karel Šmejkal and
  • Kannan R.R. Rengasamy

15 September 2018

Thymus bovei Benth. (TB) is an important plant in the traditional medicine of the Mediterranean region. This study investigates the health-promoting properties of TB essential oil (TB-EO) for its possible use in clinical practice with regards to its...

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J. Clin. Med. - ISSN 2077-0383