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Journal of Clinical Medicine, Volume 14, Issue 17

2025 September-1 - 428 articles

Cover Story: Before renal replacement therapy, pericarditis in end-stage renal disease patients was often associated with imminent mortality. Even if dialysis has improved the prognosis, pericarditis can still determine significant morbidity and mortality, with an incidence of 0.8–6% for dialysis-associated pericarditis. The risk of progression to cardiac tamponade is higher in dialyzed population; therefore, it is important not to delay the diagnosis and treatment of pericarditis. The therapy consists of daily hemodialysis (∼14 days), aspirin, and colchicine to reduce the risk of recurrence. When contraindicated, corticosteroids can represent an option. Pericardiocentesis is recommended for large symptomatic pericardial effusion. Pericardial window creation can be considered for dialyzed patients with refractory and symptomatic pericardial effusion. View this paper
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Articles (428)

  • Systematic Review
  • Open Access
4,068 Views
20 Pages

Implementation of Evidence-Based Psychological Treatments to Address Depressive Disorders: A Systematic Review

  • Rosa Lorente-Català,
  • Amanda Díaz-García,
  • Irene Jaén,
  • Margalida Gili,
  • Fermín Mayoral,
  • Javier García-Campayo,
  • Yolanda López-Del-Hoyo,
  • Adoración Castro,
  • María M. Hurtado and
  • Azucena García-Palacios
  • + 1 author

8 September 2025

Background: The depressed population needs to be treated and they do not have access to evidenced-based psychological practices (EBPPs). The consequences lead to significant daily impairments and huge economical costs. A large amount of research has...

  • Article
  • Open Access
1,682 Views
11 Pages

8 September 2025

Introduction: High performance colonoscopy requires the monitoring of an individual’s adenoma detection rate (ADR). The Endocuff (EndoCuff Vision, Olympus America Inc., Center Valley, PA, USA) is an endoscopic distal attachment device that incr...

  • Article
  • Open Access
1 Citations
1,016 Views
13 Pages

Missing Data in OHCA Registries: How Imputation Methods Affect Research Conclusions—Paper I

  • Stella Jinran Zhan,
  • Seyed Ehsan Saffari,
  • Marcus Eng Hock Ong and
  • Fahad Javaid Siddiqui

8 September 2025

Background/Objectives: Clinical observational studies often encounter missing data, which complicates association evaluation with reduced bias while accounting for confounders. This is particularly challenging in multi-national registries such as tho...

  • Article
  • Open Access
909 Views
12 Pages

Diabetes and Adverse Reproductive Outcomes in a Group of Mongolian Women: A Comparative Study with Non-Diabetic Subjects

  • Bolor-Erdene Sarankhuu,
  • Enkhjin Gantsolmon,
  • Khangai Enkhtugs,
  • Yanjmaa Sankhuu,
  • Chantsaldulam Purevdorj,
  • Seong-Lan Yu,
  • Seok-Rae Park,
  • Oyuntugs Byambasukh and
  • Jaeku Kang

8 September 2025

Background/Objectives: Diabetes mellitus (DM) poses an increasing burden in Mongolia, yet its impact on reproductive outcomes remains underexplored. This study aimed to compare pregnancy outcomes between diabetic and non-diabetic women and assess whe...

  • Systematic Review
  • Open Access
1 Citations
2,138 Views
17 Pages

Predictability of Lower Incisor Intrusion with Clear Aligners: A Systematic Review of Efficacy and Influencing Factors

  • David Emilio Fracchia,
  • Denis Bignotti,
  • Stefano Lai,
  • Eric Battista,
  • Alessio Verdecchia and
  • Enrico Spinas

8 September 2025

Background/Objectives: This systematic review aimed to evaluate the effectiveness and predictability of lower incisor intrusion with clear aligners in permanent dentition, addressing one of the most challenging aspects of vertical tooth movement cont...

  • Article
  • Open Access
679 Views
14 Pages

Extracorporeal Life Support in a Porcine Model of Septic Endotoxemia with Acute Pulmonary Hypertension: An Experimental Study

  • Stany Sandrio,
  • Joerg Krebs,
  • Tobias Spanier,
  • Grietje Beck,
  • Manfred Thiel and
  • Peter Tobias Graf

8 September 2025

Background: This study evaluated the effects of veno-arterial (V-A) and veno-venoarterial (V-VA) ECMO in a porcine model of septic endotoxemia-induced acute pulmonary arterial hypertension (PAH). Our hypotheses were as follows: (1) V-VA ECMO lowers p...

  • Review
  • Open Access
1,355 Views
13 Pages

Salvage Surgery After Non-Curative Endoscopic Submucosal Dissection for Early Colorectal Cancer: A Comprehensive Review

  • Felix Aigner,
  • Christoph Skias,
  • David Duller,
  • Sebastian Wisiak,
  • Karin Strohmeyer,
  • Zoltan Horvath and
  • Nicole Koter

8 September 2025

Endoscopic submucosal dissection (ESD) has emerged as a minimally invasive technique for treating early colorectal cancer (CRC), offering the potential for en bloc resection and precise histopathological assessment. However, when ESD results in non-c...

  • Review
  • Open Access
3 Citations
1,298 Views
18 Pages

Factor XI and Cancer: Physiopathological Linkage and Clinical Perspectives

  • Alfredo Mauriello,
  • Anna Chiara Maratea,
  • Celeste Fonderico,
  • Vincenzo Quagliariello,
  • Fabrizio Maurea and
  • Nicola Maurea

8 September 2025

Thrombotic complications are a common cause of morbidity and mortality in cancer patients. Factor XI (FXI) appears to play a direct role not only in thrombotic pathogenesis but also in cancer progression. This comprehensive review aims to define the...

  • Article
  • Open Access
1,973 Views
11 Pages

Mifepristone–Misoprostol Versus Misoprostol Alone for Early Missed Miscarriage After ART and Spontaneously Conceived Pregnancies

  • Adi Dayan-Schwartz,
  • Revital Vinitski,
  • Haya Hassan,
  • Ido Izhaki,
  • Suzan Abd Elgani,
  • Liron Kogan,
  • Shira Baram,
  • Firas Zbidat,
  • Khadeje Seh and
  • Ronit Beck-Fruchter
  • + 2 authors

8 September 2025

Background: Missed miscarriage (MM) is a common first-trimester complication. Misoprostol alone achieves moderate success, while combination therapy with mifepristone improves outcomes in spontaneous pregnancies. Evidence in assisted reproductive tec...

  • Systematic Review
  • Open Access
1,359 Views
19 Pages

Redefining Pediatric SCIWORA: A Systematic Review of the Literature on Clinical Patterns, Imaging Profiles, and Management Insights

  • Davide Palombi,
  • Marco Galeazzi,
  • Paolo Brigato,
  • Sergio De Salvatore,
  • Timothée De Saint Denis,
  • Luca Massimi,
  • Gianpiero Tamburrini and
  • Leonardo Oggiano

8 September 2025

Objectives: Among the spectrum of spinal injuries, Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) occupies a unique and challenging position. SCIWORA presents diagnostic and therapeutic challenges due to its broad clinical and radiolog...

  • Article
  • Open Access
1,145 Views
15 Pages

Clinical Predictive Factors for the Development of Short Bowel Syndrome in a Cohort of Patients with Crohn’s Disease: A Prospective Study

  • Laura Parisio,
  • Angelo Del Gaudio,
  • Jacopo Iaccarino,
  • Pierluigi Puca,
  • Guia Becherucci,
  • Gaetano Coppola,
  • Carlo Covello,
  • Federica Di Vincenzo,
  • Elisa Foscarini and
  • Alfredo Papa
  • + 13 authors

8 September 2025

Background/Objectives: Crohn’s disease (CD) is one of the most frequent causes of short bowel syndrome (SBS), a severe clinical condition with huge morbidity and social costs. SBS occurs when, following intestinal resections, the remaining smal...

  • Article
  • Open Access
1 Citations
936 Views
13 Pages

Ethnic Variation in Lipoprotein(a) Levels in the Kazakhstan Population

  • Makhabbat Bekbossynova,
  • Tatyana Ivanova-Razumova,
  • Gulzhan Myrzakhmetova,
  • Saltanat Andossova,
  • Aknur Kali,
  • Aliya Sailybayeva and
  • Timur Saliev

8 September 2025

Background: Lipoprotein(a) (Lp(a)) is a genetically determined lipoprotein that plays an independent role in the development of atherosclerotic cardiovascular disease (ASCVD). Ethnic differences in Lp(a) levels are well-documented, yet regional data...

  • Perspective
  • Open Access
2 Citations
1,885 Views
12 Pages

Association Between Periodontitis and Cancer: A Perspective Review of Mechanisms and Clinical Evidence

  • Marco Bonilla,
  • Irene Peñalver,
  • María José Mesa-López and
  • Francisco Mesa

8 September 2025

Chronic periodontitis has emerged as a potential modifiable risk factor for several tumors, yet its role remains underexplored beyond epidemiological associations. This perspective review examines the immunological and molecular interplay between per...

  • Article
  • Open Access
704 Views
13 Pages

8 September 2025

Background/Objectives: The optimal method to facilitate femoral access in patients with aortic stenosis and severe peripheral arterial disease (PAD) undergoing transcatheter aortic valve implantation (TAVI) remains unclear. This study compared the sa...

  • Article
  • Open Access
1,742 Views
13 Pages

AI Based Clinical Decision-Making Tool for Neurologists in the Emergency Department

  • Alon Gorenshtein,
  • Shiri Fistel,
  • Moran Sorka,
  • Gregory Telman,
  • Raz Winer,
  • Shlomi Peretz,
  • Dvir Aran and
  • Shahar Shelly

8 September 2025

Introduction: We aimed to prove integration of advanced machine learning methods within a robust ensemble framework can enhance clinical decision-support for neurologists managing patients in the emergency department (ED). Methods: We engineered an e...

  • Article
  • Open Access
1,311 Views
12 Pages

Artificial Intelligence Algorithm Supporting the Diagnosis of Developmental Dysplasia of the Hip: Automated Ultrasound Image Segmentation

  • Łukasz Pulik,
  • Paweł Czech,
  • Jadwiga Kaliszewska,
  • Bartłomiej Mulewicz,
  • Maciej Pykosz,
  • Joanna Wiszniewska and
  • Paweł Łęgosz

8 September 2025

Background: Developmental dysplasia of the hip (DDH), if not treated, can lead to osteoarthritis and disability. Ultrasound (US) is a primary screening method for the detection of DDH, but its interpretation remains highly operator-dependent. We prop...

  • Review
  • Open Access
2,928 Views
11 Pages

Antiplatelet Therapy in Atrial Fibrillation Patients on Direct Oral Anticoagulants Undergoing Percutaneous Coronary Intervention: Which and How

  • Luca Martini,
  • Matteo Lisi,
  • Graziella Pompei,
  • Manfredi Arioti,
  • Francesco Bendandi,
  • Michael Y. Henein,
  • Matteo Cameli and
  • Andrea Rubboli

8 September 2025

In patients on oral anticoagulation (OAC), typically for atrial fibrillation (AF), undergoing percutaneous coronary intervention (PCI), the antiplatelet drugs to be added to direct oral anticoagulant (DOAC) are aspirin and clopidogrel during the init...

  • Review
  • Open Access
2 Citations
1,999 Views
14 Pages

8 September 2025

Oncological patients or the individuals scheduled for cardiovascular surgeries are at risk of both oral and systemic complications when existing dental pathologies are not addressed before these therapies. This narrative review explores the current l...

  • Review
  • Open Access
2 Citations
1,754 Views
23 Pages

8 September 2025

Philadelphia-negative myeloproliferative neoplasms (Ph-MPNs) are clonal hematologic malignancies characterized not only by driver mutations such as JAK2V617F, CALR, and MPL but also by a profoundly dysregulated immune microenvironment. Chronic inflam...

  • Article
  • Open Access
1,117 Views
19 Pages

Patterns of Morbidity in Ambatoboeny District, Northern Madagascar: A 12-Month Study

  • Daniel Kasprowicz,
  • Krzysztof Korzeniewski and
  • Wanesa Wilczyńska

8 September 2025

Background: Ambatoboeny District in northern Madagascar faces significant health challenges due to widespread poverty, poor access to healthcare, and limited diagnostic capabilities. Despite high disease burden, data on morbidity patterns in the regi...

  • Review
  • Open Access
1,587 Views
11 Pages

The Use of JAK Inhibitors in Elderly Patients with Moderate-to-Severe Atopic Dermatitis: A Narrative Review of Clinical and Real-World Evidence

  • Giuseppe Lauletta,
  • Daniele Cecere,
  • Luca Potestio,
  • Francesca di Vico,
  • Cataldo Patruno and
  • Maddalena Napolitano

8 September 2025

Background: Atopic dermatitis (AD) in elderly patients presents unique clinical challenges due to comorbidities, polypharmacy, and an increased risk of adverse events. Janus kinase inhibitors (JAKis) have emerged as effective oral treatments, but lim...

  • Review
  • Open Access
2 Citations
2,444 Views
24 Pages

Intercostal Artery Screening with Color Doppler Thoracic Ultrasound in Pleural Procedures: A Potential Yet Underexplored Imaging Modality for Minimizing Iatrogenic Bleeding Risk in Interventional Pulmonology

  • Guido Marchi,
  • Sara Cinquini,
  • Francesco Tannura,
  • Giacomo Guglielmi,
  • Riccardo Gelli,
  • Luca Pantano,
  • Giovanni Cenerini,
  • Valerie Wandael,
  • Beatrice Vivaldi and
  • Laura Carrozzi
  • + 8 authors

7 September 2025

Hemorrhagic complications during pleural interventions—such as thoracentesis and chest tube insertion—remain a significant clinical concern, primarily due to inadvertent injury of the intercostal artery (ICA). The highly variable ICA anat...

  • Article
  • Open Access
2,416 Views
12 Pages

7 September 2025

Objectives: The purpose of this retrospective cohort study was to ascertain the risk of abortion, ectopic pregnancy and hydatidiform mole development in women with polycystic ovary syndrome (PCOS) using data from Korea’s National Health Insuran...

  • Perspective
  • Open Access
3,602 Views
16 Pages

Elective Umbilical Hernia Repair in Adults in the 21st Century: Challenging the Status Quo

  • Sergio Huerta,
  • Jared McAllister,
  • Crystal Phung and
  • Angela A. Guzzetta

7 September 2025

On the spectrum of complexity for general surgery operations, umbilical hernia repair (UHR) is on the light side. After inguinal hernias, they are the most commonly repaired hernias and, as such, umbilical hernias are an important component of a gene...

  • Article
  • Open Access
2 Citations
1,415 Views
11 Pages

Evaluation of Maxillary Molar Distalization Supported by Mini-Implants with the Advanced Molar Distalization Appliance (amda®): Preliminary Results of a Prospective Clinical Trial

  • Nikolaos Karvelas,
  • Aikaterini Samandara,
  • Bogdan Radu Dragomir,
  • Alice Chehab,
  • Tinela Panaite,
  • Cristian Romanec,
  • Moschos A. Papadopoulos and
  • Irina Nicoleta Zetu

7 September 2025

Background: Class II is considered one of the most common malocclusions, influencing 37% of schoolchildren in Europe and 33% of orthodontic patients in the United States. When this type of malocclusion is combined with increased overjet with procline...

  • Article
  • Open Access
1 Citations
1,232 Views
13 Pages

Association of the Lactate/Albumin Ratio with Mortality and Hypovolemia in Critically Ill Patients: A Retrospective Cohort Study

  • Jakub Droś,
  • Rafał Świstek,
  • Patryk Kasongo,
  • Jakub Konieczyński,
  • Piotr Bielański,
  • Agnieszka Sajdyk,
  • Anna Wrzosek,
  • Tomasz Składzień,
  • Rafał Depukat and
  • Michał Terlecki
  • + 15 authors

7 September 2025

Background/Objectives: Previous research has demonstrated that the lactate/albumin ratio (L/A) may predict mortality among critically ill patients. Based on pathophysiological rationale, L/A may also correlate with volume status, however such an asso...

  • Review
  • Open Access
1,023 Views
17 Pages

7 September 2025

Purpose: This review aims to synthesize current knowledge of anatomical variations of the popliteofibular ligament (PFL) and evaluate the clinical relevance of the classification system proposed by Olewnik et al. in the context of the diagnosis, surg...

  • Article
  • Open Access
1,234 Views
14 Pages

Oral Contraceptive Use and Reproductive History in Relation to Metabolic Syndrome Among Women from KNHANES 2010–2023

  • In Ae Cho,
  • Jaeyoon Jo,
  • Jeesun Lee,
  • Hyunjin Lim,
  • Yun-Hong Cheon and
  • Rock Bum Kim

7 September 2025

Background/Objectives: This study examined how reproductive factors—such as oral contraceptive (OC) use, age at menarche, number of pregnancies, and age at first delivery—are related to the risk of metabolic syndrome (MetS) in Korean wome...

  • Article
  • Open Access
1 Citations
2,632 Views
27 Pages

Injury Pattern According to Player Position in Male Amateur Football Players in Greece: A Retrospective Study

  • Konstantinos Vassis,
  • Ioannis Misiris,
  • Spyridon Plakias,
  • Athanasios Siouras,
  • Savvas Spanos,
  • Eleftherios Giamouridis,
  • Zacharias Dimitriadis,
  • Dimitrios Tsaopoulos and
  • Ioannis A. Poulis

7 September 2025

Background: Football has a high injury risk due to speed and contact, and injury patterns may vary by playing position. Positional roles affect physical and physiological demands and may influence injury characteristics. Although this has been examin...

  • Review
  • Open Access
1,236 Views
11 Pages

Patient-Reported Outcomes and Quality of Life After Laparoscopic Pectopexy

  • Anna Pitsillidi,
  • Georgios Grigoriadis,
  • Laura Vona,
  • Guenter Noé and
  • Angelos Daniilidis

7 September 2025

Background: Pelvic organ prolapse (POP) significantly impairs patients’ quality of life, especially in urinary, bowel, and sexual domains. While laparoscopic sacrocolpopexy (LS) is the current gold standard for apical prolapse repair, it is ass...

  • Article
  • Open Access
2,545 Views
14 Pages

Phase II Cardiac Rehabilitation Under Compulsory Insurance in Kazakhstan: A Five-Year Cohort Analysis of Clinical and Economic Outcomes

  • Yelena Sergeyeva,
  • Lyudmila S. Yermukhanova,
  • Ardak N. Nurbakyt,
  • Gulnara L. Kurmanalina,
  • Dariush Walkowiak,
  • Maral G. Nogayeva and
  • Alireza Afshar

7 September 2025

Background/Aim of Study: Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality globally. Cardiac rehabilitation (CR) plays a pivotal role in the recovery of post-acute myocardial infarction (AMI) patients. Despite evidence s...

  • Systematic Review
  • Open Access
1,693 Views
11 Pages

Tibial Anterior Cruciate Ligament Avulsion Fractures in Pediatric and Adult Populations: A Systematic Literature Review

  • Vincent Landré,
  • Michel Teuben,
  • Felix Karl-Ludwig Klingebiel,
  • Alba Shehu,
  • Falko Ensle,
  • Hans-Christoph Pape and
  • Thomas Rauer

7 September 2025

Objectives: Tibial anterior cruciate ligament avulsion fractures (TAFs) are avulsions of the anterior cruciate ligament (ACL) from its insertion at the tibial intercondylar eminence that share the same trauma mechanism as ACL tears. TAFs were initial...

  • Article
  • Open Access
1,626 Views
14 Pages

Perioperative Changes in Renal Resistive Index as a Predictor of Acute Kidney Injury After Cardiac Surgery: A Prospective Cohort Study

  • Marie Sabia,
  • Christian Isetta,
  • Rishika Banydeen,
  • Nicolas Durand,
  • Hossein Mehdaoui and
  • Marc Licker

7 September 2025

Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) is common and various tools are proposed to identify patients at risk of AKI. The determination of the Doppler-derived renal resistance index (RRI) is useful for detecting the occur...

  • Article
  • Open Access
2,801 Views
13 Pages

6 September 2025

Background/Objectives: Tinnitus often occurs alongside the emotional symptoms of anxiety and depression. The Ginkgo biloba extract EGb 761® was shown to be effective in reducing neuropsychiatric symptoms in elderly patients with both dementia and...

  • Article
  • Open Access
1,221 Views
14 Pages

6 September 2025

Background. Axillary lymph node biopsy (ALND) has traditionally been considered the gold standard for axillary staging and treatment in clinically node-positive breast cancer patients. However, in patients with nodal disease, the therapeutic benefit...

  • Article
  • Open Access
1,053 Views
10 Pages

Arthroplasty Has Surpassed Surgical Fixation for Radial Head Fractures Among ABOS Oral Examination Candidates: A 19-Year Observational Study

  • Cole M. Patrick,
  • Alexis B. Sandler,
  • Kyle J. Klahs,
  • John P. Scanaliato,
  • Michael D. Baird and
  • Nata Parnes

6 September 2025

Background/Objectives: Radial head arthroplasty (RHA) and open reduction and internal fixation (ORIF) have emerged as predominant methods of surgical management for radial head fractures. The objective of this study was to evaluate national trends in...

  • Review
  • Open Access
1,580 Views
17 Pages

Brachial Plexopathies: A Comprehensive Radiologic Method Integrating Ultrasound and MRI

  • Giulia Pacella,
  • Raffaele Natella,
  • Federico Bruno,
  • Michela Bruno,
  • Donatella Franco,
  • Daniele Giuseppe Romano and
  • Marcello Zappia

6 September 2025

Background: Brachial plexopathies comprise a diverse array of illnesses with multifactorial etiologies, including trauma, inflammation, neoplasia, and iatrogenic damage, frequently manifesting with nonspecific clinical symptoms. Precise and prompt im...

  • Review
  • Open Access
7 Citations
2,411 Views
20 Pages

6 September 2025

Background: Lennox–Gastaut syndrome (LGS) is a severe childhood-onset developmental and epileptic encephalopathy characterized by treatment-resistant seizures and significant morbidity. Despite multiple approved anti-seizure medications (ASMs),...

  • Article
  • Open Access
1,452 Views
17 Pages

Natural vs. Assisted Conception: Sleep and Emotional Health from Pregnancy to Postpartum—An Exploratory Study

  • Olympia Evagorou,
  • Aikaterini Arvaniti,
  • Spyridon Plakias,
  • Nikoleta Koutlaki,
  • Magdalini Katsikidou,
  • Sofia Sfelinioti,
  • Paschalis Steiropoulos and
  • Maria Samakouri

6 September 2025

Background/Objectives: Sleep plays a key role in female fertility. Sleep disturbances (SDis) during pregnancy are common and may negatively affect maternal health, contributing to an increased risk of perinatal depression and anxiety. Aim: The presen...

  • Article
  • Open Access
1,199 Views
12 Pages

The Reliability and Validity of a New Laryngeal Palpation Tool for Static and Dynamic Examination

  • Isabelle Bargar,
  • Melina Maria Ippers,
  • Katrin Neumann,
  • Philipp Mathmann and
  • Ben Barsties v. Latoszek

6 September 2025

Background/Objectives: Voice disorders caused by laryngeal hypertension can impact volume, quality, pitch, resonance, flexibility, and stamina. The laryngeal palpation is a tactile-perceptual assessment, which is one of a few examination methods to e...

  • Article
  • Open Access
795 Views
14 Pages

Test Learning Effects Influence Coordinative but Not Strength-Related Tasks in Patients Six Months After Anterior Cruciate Ligament Reconstruction

  • Sonja Jahnke,
  • Robert Prill,
  • Aleksandra Królikowska,
  • Łukasz Oleksy,
  • Caren Cruysen,
  • Maciej Daszkiewicz,
  • Mateusz Kowal,
  • Monika Kentel,
  • Maciej Kentel and
  • Roland Becker
  • + 2 authors

6 September 2025

Background: A comprehensive rehabilitation program is recommended following anterior cruciate ligament reconstruction (ACLR) to restore function, strength and lower limb stability. Despite advancements in surgical techniques, high reinjury rates high...

  • Article
  • Open Access
799 Views
14 Pages

Postoperative Changes in Hematological, Biochemical, and Redox Status Parameters in Spinal Osteoarthritis Patients Undergoing Spinal Decompression and Stabilization Surgery

  • Milan Mirković,
  • Jelena Kotur-Stevuljević,
  • Jelena Vekić,
  • Nataša Bogavac-Stanojević,
  • Anđelka Milić,
  • Sanja Mirković,
  • Ankica Vujović,
  • Marija Rakić,
  • Tanja Lunić and
  • Biljana Božić Nedeljković
  • + 1 author

6 September 2025

Background/Objectives: Spinal osteoarthritis (sOA) is a degenerative condition marked by pain, inflammation, and restricted mobility. While surgical interventions such as spinal decompression and stabilization are common, their impact on redox status...

  • Article
  • Open Access
1 Citations
1,843 Views
17 Pages

6 September 2025

Background: Artificial intelligence (AI) can improve efficiency, documentation, and diagnostic quality in ophthalmology. This study examined clinical AI adoption, institutional readiness, perceived utility, trust, ethical concerns, and educational ne...

  • Systematic Review
  • Open Access
2 Citations
2,130 Views
30 Pages

Fracture Patterns in Fatal Free Falls: A Systematic Review of Intrinsic and Extrinsic Risk Factors and the Role of Postmortem CT

  • Filip Woliński,
  • Kacper Kraśnik,
  • Łukasz Bryliński,
  • Jolanta Sado,
  • Justyna Sagan,
  • Katarzyna Brylińska,
  • Grzegorz Teresiński,
  • Tomasz Cywka,
  • Robert Karpiński and
  • Jacek Baj

6 September 2025

Background: Free fatal falls (FFF) represent a distinct form of blunt force trauma (BFT) that is frequently encountered in forensic practice. Distinguishing FFF injuries from other forms of BFT, such as motor vehicle accidents (MVAs), can pose challe...

  • Article
  • Open Access
2,370 Views
12 Pages

Hypercalcemia Causes More Severe Acute Pancreatitis: An International Multicenter Cohort Study

  • Gábor Gieszinger,
  • Balázs Kui,
  • Péter Hegyi,
  • Péter Jenő Hegyi,
  • Áron Vincze,
  • Bálint Erőss,
  • Andrea Szentesi,
  • Vivien Vass,
  • Zsolt Abonyi-Tóth and
  • László Czakó
  • + 8 authors

6 September 2025

Background: Hypercalcemia is a rare etiology of acute pancreatitis; only a few cases have been reported in the literature, and the severity of hypercalcemia-induced AP is unknown. We aimed to assess the occurrence and severity of hypercalcemia-induce...

  • Article
  • Open Access
643 Views
12 Pages

The Nasser–Gavvala–Shirodkar–Botchu Classification: A Classification System for Loosening of Endoprosthetic Replacements

  • Ahmed Abdul Hadi Harb Nasser,
  • Sai Niharika Gavvala,
  • Kapil Shirodkar and
  • Rajesh Botchu

6 September 2025

Objectives: The indications for femoral endoprosthesis replacement (EPR) use in limb reconstruction have broadened over the last decade. Despite its success, loosening remains the most common reason for failure. No previous system has classified loos...

  • Article
  • Open Access
1,200 Views
14 Pages

A Competing-Risks Approach to the Progression, Regression and Persistence of High-Grade Cervical Dysplasia in Patients over 30 Years Old—A Prospective Study

  • Iulian-Valentin Munteanu,
  • Demetra Socolov,
  • Razvan Socolov,
  • Ana-Maria Adam,
  • Gigi Adam,
  • Ingrid-Andrada Vasilache,
  • Petronela Vicoveanu,
  • Valeriu Harabor,
  • Anamaria Harabor and
  • Alina-Mihaela Calin

6 September 2025

Background/Objectives: In Romania, where cervical cancer incidence remains among the highest in the European Union, a risk-based management strategy could support more precise allocation of limited resources. The aim of this study was to test the pro...

  • Review
  • Open Access
2,731 Views
16 Pages

Perioperative Analgesia for Foot and Ankle Surgery: A Comprehensive Review

  • Giuseppe Pascarella,
  • Eugenio De Quattro,
  • Alessandro Strumia,
  • Romualdo Del Buono,
  • Francesca Gargano,
  • Alessandro Ruggiero,
  • Sabrina Migliorelli,
  • Lorenzo Schiavoni,
  • Alessia Mattei and
  • Fabio Costa
  • + 3 authors

6 September 2025

Foot and ankle surgery is often associated with significant postoperative pain that may delay mobilization and recovery. For this reason, effective perioperative analgesia is essential to improve outcomes, minimize opioid use, and enable safe early d...

  • Article
  • Open Access
1,715 Views
12 Pages

Long-Term Clinical Outcomes of Wedge-Shaped Implants Inserted in Narrow Ridges: A 7-Year Follow-Up Multicenter Prospective Single-Arm Cohort Study

  • Antonio Rapani,
  • Tomaso Vercellotti,
  • Claudio Stacchi,
  • Gianluca Gregorig,
  • Francesco Oreglia,
  • Emanuele Morella and
  • Teresa Lombardi

6 September 2025

Background: Wedge-shaped implants have been proposed as a minimally invasive solution for narrow alveolar ridges, aiming to avoid bone augmentation. While the short-term results are promising, long-term clinical evidence remains limited. Methods: Thi...

  • Article
  • Open Access
1,006 Views
10 Pages

Emergency Surgery for Acute Left-Sided Complicated Diverticulitis in the Elderly: What Are the Predictor Factors of Mortality and Morbidity?

  • Samuele Vaccari,
  • Basilio Pirrera,
  • Alessandro Ussia,
  • Augusto Lauro,
  • Margherita Minghetti,
  • Maurizio Cervellera,
  • Vito D’Andrea and
  • Valeria Tonini

6 September 2025

Introduction: Diverticular disease is common in Western countries, and the frequency of emergency operations for acute left-sided complicated diverticulitis (ALCD) has increased over the past 15 years. Methods: A total of 49 patients aged over 80 yea...

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J. Clin. Med. - ISSN 2077-0383