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Updates in Diabetes and Obesity in Reproductive Health

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Reproductive Medicine & Andrology".

Deadline for manuscript submissions: closed (31 October 2025) | Viewed by 915

Special Issue Editors


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Guest Editor
1. Maternal Fetal Medicine Service, Northwell Health, New York, NY, USA
2. Allen and Frances Adler Laboratory of Blood and Vascular Biology, Rockefeller University, New York, NY, USA
Interests: maternal fetal medicine; obstetric medicine; placenta-mediated complications; bleeding and thrombotic complications of pregnancy; preterm birth; perinatology
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Guest Editor
Departments of Obstetrics and Gynecology, The Edith Wolfson Medical Center Holon, Israel Affiliated with Sackler Faculty of Medicine, Tel Aviv University, P.O. Box 5, Holon 58100, Tel Aviv, Israel
Interests: maternal fetal medicine; obstetrics; perinatology sexual assault

Special Issue Information

Dear Colleagues,

Obesity and diabetes are increasingly prevalent medical conditions that pose significant challenges in reproductive health. Over the last few decades, their incidence has risen globally, including among women of childbearing age. In addition, this field has witnessed remarkable progress, with significant advances in research, clinical care, and public health strategies. These developments have improved our understanding of the complex interactions between obesity, diabetes, and reproductive health.

In this Special Issue of the Journal of Clinical Medicine, we are offering a platform to highlight the broad diversity of research conducted across this field. This Special Issue will focus on new insights, current challenges and controversies, recent advances, and future perspectives in the field of obesity and diabetes in reproductive health. We anticipate that the research presented will promote fruitful discussions between physicians and researchers from different fields of medicine that will translate into the adoption of best practice applications in clinical, public health and policy settings.

Dr. Amihai Rottenstreich
Dr. Giulia Barda
Guest Editors

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Keywords

  • obesity
  • diabetes
  • reproductive health
  • childbearing age
  • pregnancy

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Published Papers (1 paper)

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Research

12 pages, 708 KB  
Article
Diabetes and Adverse Reproductive Outcomes in a Group of Mongolian Women: A Comparative Study with Non-Diabetic Subjects
by Bolor-Erdene Sarankhuu, Enkhjin Gantsolmon, Khangai Enkhtugs, Yanjmaa Sankhuu, Chantsaldulam Purevdorj, Seong-Lan Yu, Seok-Rae Park, Oyuntugs Byambasukh and Jaeku Kang
J. Clin. Med. 2025, 14(17), 6344; https://doi.org/10.3390/jcm14176344 - 8 Sep 2025
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Abstract
Background/Objectives: Diabetes mellitus (DM) poses an increasing burden in Mongolia, yet its impact on reproductive outcomes remains underexplored. This study aimed to compare pregnancy outcomes between diabetic and non-diabetic women and assess whether diabetes duration influences adverse reproductive events. Methods: We conducted a [...] Read more.
Background/Objectives: Diabetes mellitus (DM) poses an increasing burden in Mongolia, yet its impact on reproductive outcomes remains underexplored. This study aimed to compare pregnancy outcomes between diabetic and non-diabetic women and assess whether diabetes duration influences adverse reproductive events. Methods: We conducted a cross-sectional study among 223 diabetic and 495 non-diabetic women attending outpatient clinics in Ulaanbaatar between October and December 2024. Data on reproductive history were collected using structured questionnaires. Pregnancy outcomes included miscarriage, stillbirth, abortion, and live birth. Logistic regression models were applied to assess associations, adjusting for age, marital status, education, smoking, alcohol use, age at menarche, and reproductive history. Results: Mean age was 51.7 and 50.4 years for diabetic and non-diabetic women, respectively (p = 0.222). Diabetic women had more pregnancies (median: 4.00 vs. 3.00, p < 0.001) and a higher likelihood of abortion (35.4% vs. 25.5%, p = 0.004) and miscarriage (27.8% vs. 11.1%, p < 0.001). Stillbirths were more frequent in diabetic (4.0% vs. 2.2%) but not statistically significant. Pregnancy problems (miscarriage and/or stillbirth) were more prevalent in diabetic women (29.6% vs. 12.7%, p < 0.001). In adjusted models, diabetes was associated with higher odds of pregnancy problems (aOR = 1.64, 95% CI: 1.02–2.63, p = 0.042), miscarriage (aOR = 2.03, 95% CI: 1.21–3.40, p = 0.007), and abortion (aOR = 1.58, 95% CI: 1.14–2.19, p = 0.006). A dose response pattern was observed: miscarriage risk was higher in women with diabetes ≥10 years (OR = 2.67, 95% CI: 1.55–4.62, p < 0.001) than <10 years (OR = 1.79, 95% CI: 1.08–2.96, p = 0.023). Conclusions: Diabetes is independently associated with increased risks of miscarriage and abortion in Mongolian women, with longer disease duration further elevating this risk. Full article
(This article belongs to the Special Issue Updates in Diabetes and Obesity in Reproductive Health)
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