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Journal of Clinical Medicine, Volume 13, Issue 10

May-2 2024 - 289 articles

Cover Story: Preoperative optimization of medical treatment and nutritional status, prescription of exercise program, and patient’s education to adopt healthier behaviours represent the pillars of prehabilitation program. In this narrative review, we describe the mechanisms of cardiopulmonary complications that determine quality of life and survival after major surgery and how implementation of a person-centered prehabilitation program may improve clinical outcomes and patient well-being while speeding up functional recovery. This holistic, standardized and individualized approach represents a multidisciplinary endeavour involving specialized nurses, physiotherapists, oncologists, surgeons, pneumologists and anesthesiologists, all cooperating with each other and interacting with the patient. View this paper
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Articles (289)

  • Review
  • Open Access
55 Citations
26,375 Views
15 Pages

The Surgical Stress Response and Anesthesia: A Narrative Review

  • Robert Ivascu,
  • Ligia I. Torsin,
  • Laura Hostiuc,
  • Cornelia Nitipir,
  • Dan Corneci and
  • Madalina Dutu

20 May 2024

The human physiological response “to stress” includes all metabolic and hormonal changes produced by a traumatic event at the micro or macro cellular levels. The main goal of the body’s first response to trauma is to keep physiologi...

  • Article
  • Open Access
8 Citations
2,541 Views
16 Pages

Deregulated Long Non-Coding RNAs (lncRNA) as Promising Biomarkers in Hidradenitis Suppurativa

  • Uppala Radhakrishna,
  • Uppala Ratnamala,
  • Devendrasinh D. Jhala,
  • Lavanya V. Uppala,
  • Aaren Vedangi,
  • Nazia Saiyed,
  • Maulikkumar Patel,
  • Sushma R. Shah,
  • Rakesh M. Rawal and
  • Gregor B. E. Jemec
  • + 3 authors

20 May 2024

Background/Objectives: In recent times, epigenetics alterations in Hidradenitis suppurativa (HS) have been explored and exploited translationally to guide investigation of new therapeutic approaches. On the other hand, long noncoding RNAs (LncRNAs),...

  • Systematic Review
  • Open Access
4 Citations
2,438 Views
18 Pages

Trochleoplasty Provides Good Outcomes for Recurrent Patellofemoral Dislocations with No Clear Superiority across Different Techniques

  • Sharon Si Heng Tan,
  • Gin Way Law,
  • Sunny Sunwoo Kim,
  • Ervin Sethi,
  • Andrew Kean Seng Lim and
  • James Hoi Po Hui

20 May 2024

Background: Literature is sparse on outcome comparisons between different trochleoplasty techniques in the treatment of patella instability. To date, it is unclear whether there is a technique that offers superior outcomes. This systematic review and...

  • Systematic Review
  • Open Access
6 Citations
3,531 Views
13 Pages

Pancreatic Neuroendocrine Tumors: What Is the Best Surgical Option?

  • Renato Patrone,
  • Federico Maria Mongardini,
  • Alessandra Conzo,
  • Chiara Cacciatore,
  • Giovanni Cozzolino,
  • Antonio Catauro,
  • Eduardo Lanza,
  • Francesco Izzo,
  • Andrea Belli and
  • Raffaele Palaia
  • + 4 authors

20 May 2024

Background: Pancreatic neuroendocrine tumors (pNETs) represent a rare subset of pancreatic cancer. Functional tumors cause hormonal changes and clinical syndromes, while non-functional ones are often diagnosed late. Surgical management needs multidis...

  • Editorial
  • Open Access
2 Citations
1,948 Views
5 Pages

20 May 2024

Clarifying the mechanisms by which circadian rhythms regulate biology is a central issue in directing life choices in the immediate future and presents an interesting challenge for current scientific research [...]

  • Article
  • Open Access
22 Citations
6,601 Views
18 Pages

Unlocking the Long-Term Effectiveness of Benralizumab in Severe Eosinophilic Asthma: A Three-Year Real-Life Study

  • Laura Pini,
  • Diego Bagnasco,
  • Bianca Beghè,
  • Fulvio Braido,
  • Paolo Cameli,
  • Marco Caminati,
  • Cristiano Caruso,
  • Claudia Crimi,
  • Gabriella Guarnieri and
  • Manuela Latorre
  • + 18 authors

20 May 2024

Background: Benralizumab has been shown to restore good control of severe eosinophilic asthma (SEA). Robust data on benralizumab effectiveness over periods longer than 2 years are scarce. Methods: This retrospective multicentric study was conducted o...

  • Systematic Review
  • Open Access
3 Citations
3,470 Views
20 Pages

20 May 2024

Background: This systematic review examines the efficacy of multiorgan resection (MOR) in treating locally advanced gastric cancer (LAGC), focusing on survival outcomes, postoperative morbidity, and mortality. Methods: We conducted a comprehensive se...

  • Article
  • Open Access
1 Citations
4,162 Views
13 Pages

20 May 2024

Background/Objectives: Presbyopia, a common age-related refractive error, affects over a billion people globally and significantly impacts daily life. Methods: This retrospective study analyzed 288 eyes of 144 patients undergoing LBV PRESBYOND® t...

  • Article
  • Open Access
2 Citations
2,527 Views
11 Pages

20 May 2024

Background: Graves’ ophthalmopathy (GO) is characterized by upper eyelid retraction (UER), the most prevalent clinical sign. We aimed to assess the clinical efficacy of a multimodal combination of steroids, 5-fluorouracil (5-FU), and botulinum...

  • Review
  • Open Access
6 Citations
2,813 Views
16 Pages

Acute Respiratory Failure in Autoimmune Rheumatic Diseases: A Review

  • Sofia Poli,
  • Francesca Sciorio,
  • Giorgio Piacentini,
  • Angelo Pietrobelli,
  • Luca Pecoraro and
  • Sara Pieropan

20 May 2024

This review examines respiratory complications in autoimmune rheumatic diseases within intensive care units (ICUs). The respiratory system, primarily affected in diseases like rheumatoid arthritis, systemic lupus erythematosus, and scleroderma, often...

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J. Clin. Med. - ISSN 2077-0383