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Antioxidants, Volume 9, Issue 1

January 2020 - 88 articles

Cover Story: Feline hyperthyroidism is the most common endocrinopathy in middle-aged and geriatric cats, characterized by an impairment of the redox status. Methimazole is the medical treatment of choice for the disease. However, the onset of methimazole-related side effects (i.e., hepatotoxicosis, gastrointestinal upset, vasculitis, facial pruritus, and blood dyscrasias) is likely caused by oxidative stress as well. We investigated the dietary supplementation of a mixture of antioxidants (i.e., curcumin, quercetin, resveratrol, and vitamin E) as additional treatment for hyperthyroid cats receiving methimazole. Our results showed that the antioxidants exert a protective effect against the oxidative stress induced by both the thyroid dysfunction and the administration of the drug, contributing to the reduction of methimazole-related side effects. View this paper.
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Articles (88)

  • Article
  • Open Access
79 Citations
7,749 Views
14 Pages

Evaluation of the Phenolic Profile of Castanea sativa Mill. By-Products and Their Antioxidant and Antimicrobial Activity against Multiresistant Bacteria

  • Vanessa Silva,
  • Virgílio Falco,
  • Maria Inês Dias,
  • Lillian Barros,
  • Adriana Silva,
  • Rosa Capita,
  • Carlos Alonso-Calleja,
  • Joana S. Amaral,
  • Gilberto Igrejas and
  • Isabel C. F. R. Ferreira
  • + 1 author

20 January 2020

The chestnut industry generates a large amount of by-products. These agro-industrial wastes have been described as potential sources of phenolic compounds with high bioactive potential. Therefore, we aimed to extract the phenolic compounds from chest...

  • Article
  • Open Access
8 Citations
5,514 Views
16 Pages

Hydroxycinnamyl Derived BODIPY as a Lipophilic Fluorescence Probe for Peroxyl Radicals

  • Jaroslaw Kusio,
  • Kaja Sitkowska,
  • Adrian Konopko and
  • Grzegorz Litwinienko

20 January 2020

Herein, we describe the synthesis of a fluorescent probe NB-2 and its use for the detection of peroxyl radicals. This probe is composed of two receptor segments (4-hydroxycinnamyl moieties) sensitive towards peroxyl radicals that are conjugated with...

  • Article
  • Open Access
46 Citations
6,637 Views
17 Pages

Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy

  • Dong-Yeong Lee,
  • Young-Jin Park,
  • Myung-Geun Song,
  • Deok Ryong Kim,
  • Sahib Zada and
  • Dong-Hee Kim

19 January 2020

Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the cytoprotective effects of delphinidin, a potent antioxidant, in human c...

  • Article
  • Open Access
26 Citations
5,723 Views
20 Pages

Dendropanax morbifera Protects against Renal Fibrosis in Streptozotocin-Induced Diabetic Rats

  • Richa Sachan,
  • Amit Kundu,
  • Prasanta Dey,
  • Ji Yeon Son,
  • Kyeong Seok Kim,
  • Da Eun Lee,
  • Hae Ri Kim,
  • Jae Hyeon Park,
  • Su Hyun Lee and
  • Jung-Hwan Kim
  • + 4 authors

19 January 2020

The aquatic extract of Dendropanax morbifera (DP) is typically consumed as a beverage in Korea and China and is also used in various traditional medicines. However, the functional role of DP on diabetes-induced renal fibrosis is unclear. Here, the pr...

  • Article
  • Open Access
22 Citations
4,979 Views
13 Pages

Chemoprevention of Experimental Periodontitis in Diabetic Rats with Silk Fibroin Nanoparticles Loaded with Resveratrol

  • Ana Giménez-Siurana,
  • Francisco Gómez García,
  • Ana Pagan Bernabeu,
  • Antonio Abel Lozano-Pérez,
  • Salvador D. Aznar-Cervantes,
  • José Luis Cenis and
  • Pía López-Jornet

19 January 2020

Objective: the objective of the present work is to study the effectiveness of treatment with silk fibroin nanoparticles loaded with resveratrol in experimental periodontitis in a diabetic rat model. Introduction: Periodontitis is an inflammatory path...

  • Article
  • Open Access
22 Citations
5,462 Views
11 Pages

Coenzyme Q10-Polyethylene Glycol Monostearate Nanoparticles: An Injectable Water-Soluble Formulation

  • Kengo Banshoya,
  • Tetsuya Nakamura,
  • Tetsuro Tanaka and
  • Yoshiharu Kaneo

19 January 2020

Therapeutic applications of coenzyme Q10 (CoQ10) are greatly limited by its lack of solubility in aqueous media. In this study, polyethylene glycol monostearate (stPEG) was used to construct micelles containing CoQ10 as a new formulation. The micella...

  • Review
  • Open Access
8 Citations
4,587 Views
13 Pages

Mitoprotective Clinical Strategies in Type 2 Diabetes and Fanconi Anemia Patients: Suggestions for Clinical Management of Mitochondrial Dysfunction

  • Giovanni Pagano,
  • Federico V. Pallardó,
  • Beatriz Porto,
  • Maria Rosa Fittipaldi,
  • Alex Lyakhovich and
  • Marco Trifuoggi

18 January 2020

Oxidative stress (OS) and mitochondrial dysfunction (MDF) occur in a number of disorders, and several clinical studies have attempted to counteract OS and MDF by providing adjuvant treatments against disease progression. The present review is aimed a...

  • Review
  • Open Access
192 Citations
11,736 Views
11 Pages

Selenium Anticancer Properties and Impact on Cellular Redox Status

  • Lolita Kuršvietienė,
  • Aušra Mongirdienė,
  • Jurga Bernatonienė,
  • Jurgita Šulinskienė and
  • Inga Stanevičienė

17 January 2020

(1) Background: In this review, we provide information published in recent years on the chemical forms, main biological functions and especially on antioxidant and prooxidant activities of selenium. The main focus is put on the impact of selenoprotei...

  • Article
  • Open Access
31 Citations
26,269 Views
12 Pages

Domestic Sautéing with EVOO: Change in the Phenolic Profile

  • Julián Lozano-Castellón,
  • Anna Vallverdú-Queralt,
  • José Fernando Rinaldi de Alvarenga,
  • Montserrat Illán,
  • Xavier Torrado-Prat and
  • Rosa Maria Lamuela-Raventós

16 January 2020

(1) Background: The health benefits of extra-virgin olive oil (EVOO), a key component of the Mediterranean diet, are attributed to its polyphenol profile. EVOO is often consumed cooked, and this process may degrade and transform polyphenols. (2) Meth...

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Antioxidants - ISSN 2076-3921