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Pathogens, Volume 9, Issue 6

June 2020 - 102 articles

Cover Story: In this paper, we ask whether host species impose a strong structural effect on the gut microbiota of Phlebotomine sandflies, main vectors of Leishmania spp.. Amplicon sequencing analysis of the gut microbiota in Leishmania-free P. papatasi, P. neglectus, P. tobbi, and P. similis sandflies, collected from the island of Leros, Greece, showed a strong structural effect of host genotype on the gut bacterial community. P. papatasi carried the most distinct microbiota dominated by two Spiroplasma and Wolbachia OTUs. Archaea showed a low presence of dominant OTUs belonging to methanogenic Euryarcheota, ammonia-oxidizing Thaumarcheota, and Nanoarchaeota. We provide first insights into the composition of the bacterial and archaeal community of Phlebotomus sandflies and showed that in the absence of Leishmania, host genotype is the major modulator of Phlebotomus gut microbiota. View this paper
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Articles (102)

  • Review
  • Open Access
32 Citations
9,244 Views
18 Pages

Background: Neospora caninum has been recognised world-wide, first as a disease of dogs, then as an important cause of abortions in cattle for the past thirty years. Over that time period, there have been improvements in the diagnosis of infection an...

  • Article
  • Open Access
23 Citations
6,640 Views
14 Pages

Global Prevalence Estimates of Toxascaris leonina Infection in Dogs and Cats

  • Ali Rostami,
  • Seyed Mohammad Riahi,
  • Vahid Fallah Omrani,
  • Tao Wang,
  • Andreas Hofmann,
  • Aliyar Mirzapour,
  • Masoud Foroutan,
  • Yadolah Fakhri,
  • Calum N. L. Macpherson and
  • Robin B. Gasser

Toxascaris leonina is an ascaridoid nematode of dogs and cats; this parasite affects the health of these animals. This study estimated the global prevalence of Ta. leonina infection in dogs and cats using random effects meta-analysis as well as subgr...

  • Article
  • Open Access
10 Citations
3,738 Views
12 Pages

Clinical Features Associated with Strongyloidiasis in Migrants and the Potential Impact of Immunosuppression: A Case Control Study

  • Angela Martinez-Pérez,
  • Manuel Jesús Soriano-Pérez,
  • Fernando Salvador,
  • Joan Gomez-Junyent,
  • Judith Villar-Garcia,
  • Miguel Santin,
  • Carme Muñoz,
  • Ana González-Cordón,
  • Joaquín Salas-Coronas and
  • Elena Sulleiro
  • + 9 authors

Strongyloides stercoralis is a widely distributed nematode more frequent in tropical areas and particularly severe in immunosuppressed patients. The aim of this study was to determine factors associated with strongyloidiasis in migrants living in a n...

  • Review
  • Open Access
3 Citations
5,032 Views
19 Pages

Human papillomavirus (HPV) infection leads to a variety of benign lesions and malignant tumors such as cervical cancer and head and neck squamous cell carcinoma. Several HPV vaccines have been developed that can help to prevent cervical carcinoma, bu...

  • Case Report
  • Open Access
8 Citations
4,902 Views
5 Pages

Actinotignum schaalii is an anaerobic, gram-positive commensal organism of the urogenital tract. A. schaalii typically causes urinary tract infections, predominantly in the elderly. Here, we describe the first case of A. schaalii infection presenting...

  • Article
  • Open Access
14 Citations
4,682 Views
18 Pages

In Silico Design and Validation of OvMANE1, a Chimeric Antigen for Human Onchocerciasis Diagnosis

  • Cabirou Mounchili Shintouo,
  • Robert Adamu Shey,
  • Derrick Neba Nebangwa,
  • Kevin K. Esoh,
  • Nkemngo Francis Nongley,
  • Joel Ebai Nguve,
  • Philippe Giron,
  • Léon Mutesa,
  • Luc Vanhamme and
  • Jacob Souopgui
  • + 2 authors

The public health goal of onchocerciasis in Africa has advanced from control to elimination. In this light, accurate diagnosis is necessary to determine treatment endpoints and confirm elimination, as well as to conduct surveillance for the identific...

  • Article
  • Open Access
14 Citations
4,441 Views
14 Pages

S-methyl Methanethiosulfonate: Promising Late Blight Inhibitor or Broad Range Toxin?

  • Charlotte Joller,
  • Mout De Vrieze,
  • Aboubakr Moradi,
  • Claudine Fournier,
  • Delphine Chinchilla,
  • Floriane L’Haridon,
  • Sebastien Bruisson and
  • Laure Weisskopf

(1) Background: S-methyl methanethiosulfonate (MMTS), a sulfur containing volatile organic compound produced by plants and bacterial species, has recently been described to be an efficient anti-oomycete agent with promising perspectives for the contr...

  • Editorial
  • Open Access
9 Citations
3,125 Views
4 Pages

Antimicrobial Resistance is one of the major Global Health challenges of the twenty-first century, and one of the World Health Organization’s (WHO) top ten global health threats. The evolution of antibiotic resistance among bacterial pathogens...

  • Article
  • Open Access
40 Citations
5,872 Views
8 Pages

Comparison of Diagnostic Tools for the Detection of Dirofilaria immitis Infection in Dogs

  • Rossella Panarese,
  • Roberta Iatta,
  • Jairo Alfonso Mendoza-Roldan,
  • Donald Szlosek,
  • Jennifer Braff,
  • Joe Liu,
  • Frédéric Beugnet,
  • Filipe Dantas-Torres,
  • Melissa J. Beall and
  • Domenico Otranto

In the last two decades, reports of canine heartworm (HW) infection have increased even in non-endemic areas, with a large variability in prevalence data due to the diagnostic strategy employed. This study evaluated the relative performance of two mi...

  • Article
  • Open Access
42 Citations
5,516 Views
15 Pages

MLVA-16 Genotyping of Brucella abortus and Brucella melitensis Isolates from Different Animal Species in Egypt: Geographical Relatedness and the Mediterranean Lineage

  • Gamal Wareth,
  • Mohamed El-Diasty,
  • Falk Melzer,
  • Gernot Schmoock,
  • Shawky A. Moustafa,
  • Mohamed El-Beskawy,
  • Dali F. Khater,
  • Mahmoud E.R. Hamdy,
  • Hoda M. Zaki and
  • Ana Cristina Ferreira
  • + 8 authors

Brucellosis is a common zoonotic disease in Egypt. However, there are limited data available on the genetic diversity of brucellae circulating in Egypt and other Mediterranean areas. One hundred and nine Brucella (B.) strains were isolated from diffe...

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Pathogens - ISSN 2076-0817