Table of Contents
Cells, Volume 8, Issue 9 (September 2019)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story (view full-size image) Intermediate filaments (also known as nanofilaments) of astrocytes are dynamic structures involved [...] Read more. Intermediate filaments (also known as nanofilaments) of astrocytes are dynamic structures involved in cell signaling and migration and determining cell responses in health, disease, and regeneration. Upregulation of the intermediate filament proteins GFAP, vimentin (VIM), and nestin is a hallmark of reactive gliosis, which is protective in ischemic stroke or neurotrauma, but inhibits some regenerative responses. Immature astrocytes from mice with VIM mutations of serine sites phosphorylated during mitosis (VIMSA/SA) exhibit cytokinetic failure and contain VIM accumulations that colocalize with mitochondria (green: VIM-containing intermediate filaments and VIM accumulations; red: mitochondria). This phenotype is transient and disappears with VIMSA/SA astrocyte maturation and can be alleviated by the inhibition of cell proliferation. View this paper.