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Micromachines, Volume 8, Issue 11

2017 November - 26 articles

Cover Story: Microfluidic devices have been widely used for cell migration research. However, most studies have focused on single cell types in simplified microenvironments. In addition, very few microfluidic cell migration studies have involved clinical samples. Therefore, more sophisticated microfluidic systems are required to model the complex in vivo microenvironment at the organ level and to explore cell migration-related clinical applications. In this paper, we review the development of cell migration studies using organ-on-chip-related approaches. View the paper here.
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Articles (26)

  • Article
  • Open Access
7 Citations
6,108 Views
12 Pages

22 November 2017

In recent years, dielectric elastomer actuators (DEAs) have been widely used in soft robots and artificial bio-medical applications. Most DEAs are composed of a thin dielectric elastomer layer sandwiched between two compliant electrodes. DEAs vary in...

(This article belongs to the Special Issue Locomotion at Small Scales: From Biology to Artificial Systems)
  • Article
  • Open Access
39 Citations
5,017 Views
16 Pages

Research on the Strategy of Motion Constraint-Aided ZUPT for the SINS Positioning System of a Shearer

  • Hai Yang,
  • Wei Li,
  • Tao Luo,
  • Haibo Liang,
  • He Zhang,
  • Yaxiong Gu and
  • Chengming Luo

22 November 2017

The accurate measurement of position and orientation for shearers is a key technology in realizing an automated, fully-mechanized, coal mining face. Since Global Positioning System (GPS) signal cannot arrive at the coal mine underground, wireless sen...

  • Article
  • Open Access
21 Citations
6,354 Views
15 Pages

22 November 2017

To determine the degree of cancer cell killing after treatment with chemotherapeutic drugs, we have developed a sensitive platform using localized surface plasmon resonance (LSPR) and aptamers to detect the extracellular cytochrome-c (cyto-c), a mito...

  • Article
  • Open Access
12 Citations
4,608 Views
9 Pages

21 November 2017

The machining of thin-walled double side freeform component has many challenges in terms of the geometrical complexity, high-requirement accuracy, and especially low stiffness. This paper surveys the filling method during the milling processes of thi...

(This article belongs to the Special Issue Ultraprecision Machining Technology—Manufacture and Metrology of Structured and Freeform Surfaces for Functional Applications)
  • Review
  • Open Access
45 Citations
12,486 Views
28 Pages

21 November 2017

Radiopharmaceuticals labeled with short-lived positron-emitting or gamma-emitting isotopes are injected into patients just prior to performing positron emission tomography (PET) or single photon emission tomography (SPECT) scans, respectively. These...

(This article belongs to the Special Issue Integrated Microfluidics for Chemical Synthesis and Analysis)
  • Article
  • Open Access
48 Citations
7,933 Views
10 Pages

A Microfluidic Device for Culturing an Encapsulated Ovarian Follicle

  • Aziz Ur Rehman Aziz,
  • Mengjie Fu,
  • Jiu Deng,
  • Chunyang Geng,
  • Yong Luo,
  • Bingcheng Lin,
  • Xiaohui Yu and
  • Bo Liu

20 November 2017

Microfluidic chips have been proved effective in mimicking different organs of human body. Simulating human ovarian follicles by microfluidic device will be useful in exploring the mechanism of folliculogenesis and related diseases. In this paper, a...

  • Review
  • Open Access
65 Citations
12,918 Views
25 Pages

Coalescence Processes of Droplets and Liquid Marbles

  • Jing Jin,
  • Chin Hong Ooi,
  • Dzung Viet Dao and
  • Nam-Trung Nguyen

20 November 2017

The coalescence process of droplets and, more recently, of liquid marbles, has become one of the most essential manipulation schemes in digital microfluidics. This process is indispensable for realising microfluidic functions such as mixing and react...

(This article belongs to the Special Issue Droplet Microfluidics: Techniques and Technologies, Volume II)
  • Article
  • Open Access
14 Citations
6,407 Views
11 Pages

Fabrication and Actuation of an Electrowetting Droplet Array on a Flexible Substrate

  • Kari L. Van Grinsven,
  • Alireza Ousati Ashtiani and
  • Hongrui Jiang

18 November 2017

Electrowetting-on-dielectric (EWOD) is a fast, well-established actuation method for a variety of applications, from microfluidics to electrowetting displays to electrowetting lenses. We therefore seek to develop a robust, scalable fabrication method...

  • Review
  • Open Access
127 Citations
18,050 Views
53 Pages

18 November 2017

Conductometric gas sensors facilitated by photons have been investigated for decades. Light illumination may enhance device attributes including operational temperature, sensing sensitivity and selectivity. This paper aims to provide an overview on t...

  • Article
  • Open Access
5 Citations
6,710 Views
8 Pages

Microfluidic Droplet Extraction by Hydrophilic Membrane

  • Shilun Feng,
  • Micheal N. Nguyen and
  • David W. Inglis

16 November 2017

Droplet-based microfluidics are capable of transporting very small amounts of fluid over long distances. This characteristic may be applied to conventional fluid delivery using needles if droplets can be reliably expelled from a microfluidic channel....

(This article belongs to the Collection Lab-on-a-Chip)
  • Feature Paper
  • Article
  • Open Access
8 Citations
6,475 Views
7 Pages

Label-Free Monitoring of Diffusion in Microfluidics

  • Kristian Tølbøl Sørensen and
  • Anders Kristensen

9 November 2017

Label-free, real-time detection of concentration gradients is demonstrated in a microfluidic H-filter, using an integrated photonic crystal slab sensor to monitor sample refractive index with spatial resolution. The recorded diffusion profiles reveal...

  • Article
  • Open Access
10 Citations
6,244 Views
12 Pages

9 November 2017

Among multi-gate field effect transistor (FET) structures, FinFET has better short channel control and ease of manufacturability when compared to other conventional bulk devices. The radio frequency (RF) performance of FinFET is affected by gate-cont...

  • Feature Paper
  • Article
  • Open Access
27 Citations
6,725 Views
9 Pages

Rapid Prototyping of Plastic Lab-on-a-Chip by Femtosecond Laser Micromachining and Removable Insert Microinjection Molding

  • Rebeca Martínez Vázquez,
  • Gianluca Trotta,
  • Annalisa Volpe,
  • Giuseppe Bernava,
  • Vito Basile,
  • Melania Paturzo,
  • Pietro Ferraro,
  • Antonio Ancona,
  • Irene Fassi and
  • Roberto Osellame

7 November 2017

We have introduced a new hybrid fabrication method for lab-on-a-chip devices through the combination of femtosecond laser micromachining and removable insert micro-injection molding. This method is particularly suited for the fast prototyping of new...

(This article belongs to the Special Issue Ultrafast Laser Fabrication for Lab-on-a-Chip)
  • Article
  • Open Access
10 Citations
5,870 Views
16 Pages

6 November 2017

In this work, we focus on investigating electrothermal flow in rotating electric fields (ROT-ETF), with primary attention paid to the horizontal traveling-wave electrothermal (TWET) vortex induced at the center of the electric field. The frequency-de...

(This article belongs to the Special Issue Micro/Nano-Chip Electrokinetics, Volume II)
  • Article
  • Open Access
14 Citations
4,911 Views
12 Pages

3 November 2017

Input saturation is a widespread phenomenon in the field of instrumentation, and is harmful to performance and robustness. In this paper, a control design framework based on composite nonlinear feedback (CNF) and integral sliding mode (ISM) technique...

(This article belongs to the Special Issue MEMS Mirrors)
  • Review
  • Open Access
20 Citations
10,272 Views
20 Pages

31 October 2017

Microfluidic devices have been widely used for cell migration research over the last two decades, owing to their attractive features in cellular microenvironment control and quantitative single-cell migration analysis. However, the majority of the mi...

(This article belongs to the Special Issue Integrated Microfluidics for Chemical Synthesis and Analysis)
  • Article
  • Open Access
15 Citations
8,361 Views
13 Pages

A Numerical Research of Herringbone Passive Mixer at Low Reynold Number Regime

  • Dongyang Wang,
  • Dechun Ba,
  • Kun Liu,
  • Ming Hao,
  • Yang Gao,
  • Zhiyong Wu and
  • Qi Mei

31 October 2017

Passive mixing based on microfluidics has won its popularity for its unique advantage, including easier operation, more efficient mixing performance and higher access to high integrity. The time-scale and performance of mixing process are usually cha...

(This article belongs to the Special Issue Passive Micromixers)
  • Article
  • Open Access
9 Citations
4,411 Views
11 Pages

Indoor Pedestrian Navigation Based on Conditional Random Field Algorithm

  • Mingrong Ren,
  • Hongyu Guo,
  • Jingjing Shi and
  • Juan Meng

30 October 2017

Foot-mounted micro-electromechanical systems (MEMS) inertial sensors based on pedestrian navigation can be used for indoor localization. We previously developed a novel zero-velocity detection algorithm based on the variation in speed over a gait cyc...

  • Feature Paper
  • Article
  • Open Access
6 Citations
4,670 Views
9 Pages

Investigation of Production Limits in Manufacturing Microstructured Surfaces Using Micro Coining

  • Michael Zahner,
  • Lukas Lentz,
  • Felix Steinlein and
  • Marion Merklein

30 October 2017

The application of microstructured surfaces is one possible method to reduce friction in lubricated contacts between components with relative movement. Due to this, the energy efficiency and the occurring wear during the operating time of the final p...

(This article belongs to the Special Issue Ultraprecision Machining Technology—Manufacture and Metrology of Structured and Freeform Surfaces for Functional Applications)
  • Article
  • Open Access
50 Citations
8,968 Views
18 Pages

30 October 2017

Single-crystal silicon microlens arrays are increasingly required in advanced infrared optics. In this study, the authors attempted to fabricate hexagonal microlens arrays, which offer high optical efficiency, on a single-crystal silicon wafer using...

(This article belongs to the Special Issue Ultraprecision Machining Technology—Manufacture and Metrology of Structured and Freeform Surfaces for Functional Applications)
  • Article
  • Open Access
11 Citations
5,623 Views
8 Pages

Acousto-Plasmonic Sensing Assisted by Nonlinear Optical Interactions in Bimetallic Au-Pt Nanoparticles

  • Eric Abraham Hurtado-Aviles,
  • Jesús Alejandro Torres,
  • Martín Trejo-Valdez,
  • Guillermo Urriolagoitia-Sosa,
  • Isaela Villalpando and
  • Carlos Torres-Torres

28 October 2017

A strong influence of mechanical action in nonlinear optical transmittance experiments with bimetallic nanoparticles integrated by gold and platinum was observed. The nanostructured samples were synthesized by a sol-gel method and contained in an eth...

(This article belongs to the Special Issue Medical Microdevices and Micromachines)
  • Article
  • Open Access
20 Citations
8,141 Views
11 Pages

Rethinking the Design of Low-Cost Point-of-Care Diagnostic Devices

  • Faith W. Kimani,
  • Samuel M. Mwangi,
  • Benjamin J. Kwasa,
  • Abdi M. Kusow,
  • Benjamin K. Ngugi,
  • Jiahao Chen,
  • Xinyu Liu,
  • Rebecca Cademartiri and
  • Martin M. Thuo

27 October 2017

Reducing the global diseases burden requires effective diagnosis and treatment. In the developing world, accurate diagnosis can be the most expensive and time-consuming aspect of health care. Healthcare cost can, however, be reduced by use of afforda...

(This article belongs to the Special Issue Paper-Based Transducers and Electronics)
  • Article
  • Open Access
11 Citations
4,852 Views
9 Pages

26 October 2017

Picosecond laser drilling was studied in the case of industrial steel and aluminum, which are difficult to microprocess by conventional methods. The dependence of hole morphology and dimensions on the pulse repetition rate and number of pulses in wat...

  • Article
  • Open Access
18 Citations
5,916 Views
14 Pages

Microfluidical Microwave Reactor for Synthesis of Gold Nanoparticles

  • Jan Macioszczyk,
  • Olga Rac-Rumijowska,
  • Piotr Słobodzian,
  • Helena Teterycz and
  • Karol Malecha

26 October 2017

Microwave treatment can reduce the time of selected syntheses, for instance of gold nanoparticles (AuNPs), from several hours to a few minutes. We propose a microfluidic structure for enhancing the rate of chemical reactions using microwave energy. T...

(This article belongs to the Special Issue Integrated Microfluidics for Chemical Synthesis and Analysis)
  • Article
  • Open Access
6 Citations
4,760 Views
11 Pages

26 October 2017

Scanning broadband light interferometry (SBLI) has been widely utilized in surface metrology due to its non-contact and high-accuracy method. In SBLI, phase evaluation through Fourier Transform (FT) is a prevalent and efficient technique, where the t...

  • Article
  • Open Access
6 Citations
4,498 Views
11 Pages

25 October 2017

In the capillary venules, blood cells auto-separate with red blood cells aggregating near the centre of vessel and the nucleated cells marginating toward the wall of vessel. In this experiment, we used cell margination to help enrich the Jurkat cells...

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Micromachines - ISSN 2072-666X