You are currently viewing a new version of our website. To view the old version click .

Toxins, Volume 17, Issue 5

May 2025 - 51 articles

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story: Lachesis (Bushmaster) envenomations pose severe clinical challenges across Central and South America due to the delivery of potent venom in massive quantities. Our comparative study of L. muta (Surinam, French Guiana) and L. stenophrys (Costa Rica, Panama) revealed consistent pseudo-procoagulant activity when tested against human plasma and fibrinogen. Both PoliVal-ICP and Antivipmyn-Tri antivenoms effectively neutralized coagulotoxic effects, with ICP demonstrating superior neutralization capacity. These findings highlight the remarkable biochemical conservation in Lachesis venom, explaining the observed cross-neutralization potential of current antivenom therapies—crucial information that may inform region-specific snakebite treatment protocols throughout the Americas. View this paper

Articles (51)

  • Review
  • Open Access
1 Citations
1,974 Views
13 Pages

Botulinum Toxin in Pain-Related Post-Stroke Limb Spasticity: A Meta-Analysis of Early and Late Injections

  • Frances Marie Tamayo,
  • Raymond Rosales,
  • Jörg Wissel,
  • Bo Biering-Sørensen,
  • Joshua Nathaniel Ellano and
  • David Simpson

21 May 2025

Spasticity is a common complication associated with stroke, and around 72% of stroke patients will develop pain during the disease. Botulinum toxin (BoNT) is a safe and efficacious treatment for spasticity and can improve associated complications, in...

  • Article
  • Open Access
692 Views
18 Pages

21 May 2025

Climate change and anthropogenic alterations in biogeochemical cycles are intensifying the frequency, duration, and potential toxicity of harmful algal blooms (HABs) in marine ecosystems. However, these effects are highly variable and depend on speci...

  • Review
  • Open Access
1 Citations
2,206 Views
16 Pages

Clinical Evidence of Bee Venom Acupuncture for Ankle Pain: A Review of Clinical Research

  • Soo-Hyun Sung,
  • Hyein Jeong,
  • Jong-Hyun Park,
  • Minjung Park and
  • Gihyun Lee

21 May 2025

The prevalence of ankle pain in adults is 9–15%, with up to 45% of sports-related injuries attributed to ankle pain and injuries. If ankle pain is not controlled in a timely manner, it can lead to ankle instability, resulting in further damage,...

  • Systematic Review
  • Open Access
1 Citations
1,825 Views
25 Pages

Effect of Ochratoxin A (OTA) on the Immune System: A Systematic Review

  • Yusif Mubarik,
  • Shadrach Tetteh Boyetey,
  • Anastasia Rosebud Aikins and
  • Mohamed Mutocheluh

20 May 2025

Ochratoxin A (OTA) is a mycotoxin with different adverse health effects. The authors conducted a systematic review to evaluate the effects of OTA on the immune system, with more emphasis on its effects on immune system organs, innate and adaptive imm...

  • Systematic Review
  • Open Access
1,361 Views
25 Pages

Systematic Review on CyanoHABs in Central Asia and Post-Soviet Countries (2010–2024)

  • Kakima Kastuganova,
  • Galina Nugumanova and
  • Natasha S. Barteneva

20 May 2025

Cyanobacterial harmful blooms (CyanoHABs) in lakes, estuaries, and freshwater reser-voirs represent a significant risk to water authorities worldwide due to their cyanotoxins and economic impacts. The duration, spread, and severity of CyanoHABs have...

  • Article
  • Open Access
681 Views
17 Pages

Heterologous Overexpression of Cytochrome P450BM3 from Bacillus megaterium and Its Role in Gossypol Reduction

  • Wenpeng Fan,
  • Jingjing Cui,
  • Tongxiang Xu,
  • Shiheng Xu,
  • Zulibina Ainiwaer,
  • Qiyu Luo and
  • Caidie Wang

20 May 2025

Gossypol is a polyphenolic toxic compound present in cotton plants. To determine whether the candidate cytochrome P450BM3 enzymes could reduce gossypol in vitro, functional recombinant cytochrome P450BM3 enzymes were successfully expressed in E. coli...

  • Review
  • Open Access
1 Citations
1,067 Views
30 Pages

Insecticidal Activities of Diterpene Alkaloids in Plants of the Genera Aconitum and Delphinium

  • Jinqiu Wang,
  • Luchuan Zheng,
  • Wenxi Huang,
  • Linxuan Li,
  • Jialian Yuan and
  • Lin Chen

20 May 2025

As the global population grows, food security and agricultural productivity face challenges, and insect pests cause significant losses to crops. The effectiveness of traditional chemical pesticides is declining, and eco-friendly pesticides need to be...

  • Article
  • Open Access
1,392 Views
13 Pages

A Comprehensive Probabilistic Risk Assessment Strategy of Aflatoxin B1 Exposure from Medical Areca Nuts Consumption

  • Tian-Tian Zuo,
  • Ya-Zhong Zhang,
  • Hong-Yan Zhai,
  • Rong-Yao Chen,
  • Jing-Zhe Pu,
  • Hong-Yu Jin,
  • Jing Liu,
  • Xian-Long Cheng and
  • Feng Wei

19 May 2025

Aflatoxin B1 (AFB1) is widely found and substantially impends public health. The current work aimed to assess AFB1 in medical areca nuts in China. The average content of AFB1 was 13.0 μg/kg, and the maximum content was 146.0 μg/kg. Furthermore,...

  • Article
  • Open Access
1,005 Views
23 Pages

Impact of Low-Level Ergot Alkaloids and Endophyte Presence in Tall Fescue Grass on the Metabolome and Microbiome of Fall-Grazing Steers

  • Ignacio M. Llada,
  • Jeferson M. Lourenco,
  • Madison M. Dycus,
  • Jessica M. Carpenter,
  • Zachery R. Jarrell,
  • Dean P. Jones,
  • Garret Suen,
  • Nicholas S. Hill and
  • Nikolay M. Filipov

17 May 2025

Fescue toxicosis (FT) is a mycotoxin-related disease caused by the ingestion of tall fescue, naturally infected with the ergot alkaloid (EA)-producing endophyte Epichloë coenophiala. Some grazing on endophyte-free (E−) or non-toxic (NT), c...

  • Article
  • Open Access
984 Views
15 Pages

Ustilaginoidin D Induces Acute Toxicity and Hepatotoxicity in Mice

  • Bo Wang,
  • Xiaolong Bai,
  • Min Zhang,
  • Xiangxiang Liu,
  • Muhammad Zulqar Nain Dara,
  • Lingjing Liu,
  • Mingming Ou,
  • Dayong Li,
  • Jiyang Wang and
  • Ling Liu
  • + 1 author

17 May 2025

Ustilaginoidin D is a type of bis-naphtho-γ-pyrone mycotoxin produced by Ustilaginoidea virens, the causal agent of rice false smut. Although previous studies have demonstrated the inhibitory effect of ustilaginoidin D on ATP synthesis and canc...

of 6