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Nutrients, Volume 14, Issue 5

March-1 2022 - 212 articles

Cover Story: Three classes of molecules present in chicory root were analyzed: fructose, chlorogenic acids, and sesquiterpene lactones. Experiments on the murine model led us to a nutrigenomic analysis, a metabolic hormone assay, and a gut microbiota analysis, associated with in vitro observations for different responses. We have highlighted a large number of effects of all these classes of molecules that suggest a pro-apoptotic activity, an anti-inflammatory, antimicrobial, antioxidant, hypolipidemic, and hypoglycemic effect, and a prebiotic role. Fructose seems to be the most involved in these activities, contributing to approximately 83% of recorded responses, but the other classes of tested molecules have shown a specific role for these different effects, with an estimated contribution of 23–24%. View this paper
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Articles (212)

  • Article
  • Open Access
4 Citations
4,911 Views
17 Pages

Soy Formula Is Not Estrogenic and Does Not Result in Reproductive Toxicity in Male Piglets: Results from a Controlled Feeding Study

  • Martin J. J. Ronis,
  • Horacio Gomez-Acevedo,
  • Kartik Shankar,
  • Leah Hennings,
  • Neha Sharma,
  • Michael L. Blackburn,
  • Isabelle Miousse,
  • Harry Dawson,
  • Celine Chen and
  • Kelly E. Mercer
  • + 1 author

7 March 2022

Soy infant formula which is fed to over half a million infants per year contains isoflavones such as genistein, which have been shown to be estrogenic at high concentrations. The developing testis is sensitive to estrogens, raising concern that the u...

  • Article
  • Open Access
6 Citations
3,370 Views
12 Pages

7 March 2022

Selenium deficiency during the perinatal period programs metabolic dysfunction in offspring. Postnatal exercise may prevent the development of programmed metabolic disease. This study investigated the impact of selenium deficiency on offspring exerci...

  • Article
  • Open Access
30 Citations
13,430 Views
13 Pages

The Effect of Oral Probiotics (Streptococcus Salivarius k12) on the Salivary Level of Secretory Immunoglobulin A, Salivation Rate, and Oral Biofilm: A Pilot Randomized Clinical Trial

  • Ksenia Babina,
  • Dilara Salikhova,
  • Maria Polyakova,
  • Oxana Svitich,
  • Roman Samoylikov,
  • Samya Ahmad El-Abed,
  • Alexandr Zaytsev and
  • Nina Novozhilova

7 March 2022

We aimed to assess the effect of oral probiotics containing the Streptococcus salivarius K12 strain on the salivary level of secretory immunoglobulin A, salivation rate, and oral biofilm. Thirty-one consenting patients meeting the inclusion criteria...

  • Article
  • Open Access
4 Citations
3,442 Views
8 Pages

A Decentralized Study Setup Enables to Quantify the Effect of Polymerization and Linkage of α-Glucans on Post-Prandial Glucose Response

  • Frederik Delodder,
  • Andreas Rytz,
  • Fabien Foltzer,
  • Lisa Lamothe,
  • Carmine d’Urzo,
  • Ludivine Feraille-Naze,
  • Julia Mauger,
  • Justine Morlet,
  • Nathalie Piccardi and
  • Lionel Philippe
  • + 3 authors

7 March 2022

The complexity of the carbohydrate structure is associated with post-prandial glucose response and diverse health benefits. The aim of this study was to determine whether, thanks to the usage of minimally invasive glucose monitors, it was possible to...

  • Article
  • Open Access
6 Citations
2,559 Views
10 Pages

Altered Serum Acylcarnitines Profile after a Prolonged Stay in Intensive Care

  • Anne-Françoise Rousseau,
  • Sarah Schmitz,
  • Etienne Cavalier,
  • Benoit Misset and
  • François Boemer

7 March 2022

A stay in intensive care unit (ICU) exposes patients to a risk of carnitine deficiency. Moreover, acylated derivates of carnitine (acylcarnitines, AC) are biomarkers for metabolic mitochondrial dysfunction that have been linked to post-ICU disorders....

  • Article
  • Open Access
17 Citations
3,810 Views
11 Pages

Dietary Sodium and Potassium Intake and Risk of Non-Fatal Cardiovascular Diseases: The Million Veteran Program

  • Dong D. Wang,
  • Yanping Li,
  • Xuan-Mai T. Nguyen,
  • Rebecca J. Song,
  • Yuk-Lam Ho,
  • Frank B. Hu,
  • Walter C. Willett,
  • Peter W. F. Wilson,
  • Kelly Cho and
  • J. Michael Gaziano
  • + 2 authors

7 March 2022

Objective: To examine the association between intakes of sodium and potassium and the ratio of sodium to potassium and incident myocardial infarction and stroke. Design, Setting and Participants: Prospective cohort study of 180,156 Veterans aged 19 t...

  • Feature Paper
  • Review
  • Open Access
35 Citations
9,542 Views
14 Pages

The Effects of Enteral Nutrition in Critically Ill Patients with COVID-19: A Systematic Review and Meta-Analysis

  • Omorogieva Ojo,
  • Osarhumwese Osaretin Ojo,
  • Qianqian Feng,
  • Joshua Boateng,
  • Xiaohua Wang,
  • Joanne Brooke and
  • Amanda Rodrigues Amorim Adegboye

7 March 2022

Background: Patients who are critically ill with COVID-19 could have impaired nutrient absorption due to disruption of the normal intestinal mucosa. They are often in a state of high inflammation, increased stress and catabolism as well as a signific...

  • Article
  • Open Access
4 Citations
5,030 Views
11 Pages

7 March 2022

The elimination of obesity is essential to maintaining good health. Medium-chain triglycerides (MCTs) inhibit fat accumulation. However, studies examining energy expenditure and fat oxidation with continuous ingestion of MCTs show little association...

  • Article
  • Open Access
7 Citations
3,988 Views
13 Pages

Beneficial In Vitro Effects of a Low Myo-Inositol Dose in the Regulation of Vascular Resistance and Protein Peroxidation under Inflammatory Conditions

  • Agata Rolnik,
  • Beata Olas,
  • Joanna Szablińska-Piernik,
  • Lesław Bernard Lahuta,
  • Andrzej Rynkiewicz,
  • Piotr Cygański,
  • Katarzyna Socha,
  • Leszek Gromadziński,
  • Michael Thoene and
  • Michał Majewski

7 March 2022

Oxidative stress induces functional changes in arteries. Therefore, the effect of myo-inositol, a possible anti-inflammatory/antioxidant agent was studied on human plasma and rat thoracic arteries. Aortic rings from male Wistar rats (3 months of age)...

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Nutrients - ISSN 2072-6643