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Nutrients, Volume 13, Issue 3

2021 March - 332 articles

Cover Story: Creatine supplementation, with and without resistance training, has shown promise for having beneficial effects on aging muscle, bone and fat mass. As a result, creatine supplementation may have therapeutic effects for older adults with sarcopenia, osteoporosis, osteosarcopenia, sarcopenic obesity, physical frailty and cachexia. View this paper
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Articles (332)

  • Article
  • Open Access
31 Citations
7,045 Views
20 Pages

Soluble Fiber Inulin Consumption Limits Alterations of the Gut Microbiota and Hepatic Fatty Acid Metabolism Caused by High-Fat Diet

  • Mayssa Albouery,
  • Alexis Bretin,
  • Bénédicte Buteau,
  • Stéphane Grégoire,
  • Lucy Martine,
  • Ségolène Gambert,
  • Alain M. Bron,
  • Niyazi Acar,
  • Benoit Chassaing and
  • Marie-Agnès Bringer

23 March 2021

Diet shapes the gut microbiota which impacts hepatic lipid metabolism. Modifications in liver fat content are associated with metabolic disorders. We investigated the extent of dietary fat and fiber-induced alterations in the composition of gut micro...

  • Review
  • Open Access
38 Citations
11,472 Views
31 Pages

The Effectiveness of Smoking Cessation, Alcohol Reduction, Diet and Physical Activity Interventions in Improving Maternal and Infant Health Outcomes: A Systematic Review of Meta-Analyses

  • Louise Hayes,
  • Catherine McParlin,
  • Liane B Azevedo,
  • Dan Jones,
  • James Newham,
  • Joan Olajide,
  • Louise McCleman and
  • Nicola Heslehurst

23 March 2021

Diet, physical activity, smoking and alcohol behaviour-change interventions delivered in pregnancy aim to prevent adverse pregnancy outcomes. This review reports a synthesis of evidence from meta-analyses on the effectiveness of interventions at redu...

  • Review
  • Open Access
89 Citations
13,081 Views
31 Pages

Adherence to Food-Based Dietary Guidelines: A Systemic Review of High-Income and Low- and Middle-Income Countries

  • Ana Carolina B. Leme,
  • Sophia Hou,
  • Regina Mara Fisberg,
  • Mauro Fisberg and
  • Jess Haines

23 March 2021

Research comparing the adherence to food-based dietary guidelines (FBDGs) across countries with different socio-economic status is lacking, which may be a concern for developing nutrition policies. The aim was to report on the adherence to FBDGs in h...

  • Review
  • Open Access
66 Citations
9,071 Views
24 Pages

Multinutrient Biofortification of Maize (Zea mays L.) in Africa: Current Status, Opportunities and Limitations

  • Nakai Goredema-Matongera,
  • Thokozile Ndhlela,
  • Cosmos Magorokosho,
  • Casper N. Kamutando,
  • Angeline van Biljon and
  • Maryke Labuschagne

23 March 2021

Macro and micronutrient deficiencies pose serious health challenges globally, with the largest impact in developing regions such as subSaharan Africa (SSA), Latin America and South Asia. Maize is a good source of calories but contains low concentrati...

  • Feature Paper
  • Review
  • Open Access
32 Citations
10,309 Views
25 Pages

Protein Substitute Requirements of Patients with Phenylketonuria on BH4 Treatment: A Systematic Review and Meta-Analysis

  • Fatma Ilgaz,
  • Cyril Marsaux,
  • Alex Pinto,
  • Rani Singh,
  • Carmen Rohde,
  • Erdem Karabulut,
  • Hülya Gökmen-Özel,
  • Mirjam Kuhn and
  • Anita MacDonald

23 March 2021

The traditional treatment for phenylketonuria (PKU) is a phenylalanine (Phe)-restricted diet, supplemented with a Phe-free/low-Phe protein substitute. Pharmaceutical treatment with synthetic tetrahydrobiopterin (BH4), an enzyme cofactor, allows a pat...

  • Article
  • Open Access
87 Citations
18,346 Views
19 Pages

The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults

  • Nicholas Edward Phillips,
  • Julie Mareschal,
  • Nathalie Schwab,
  • Emily N. C. Manoogian,
  • Sylvie Borloz,
  • Giada Ostinelli,
  • Aude Gauthier-Jaques,
  • Sylvie Umwali,
  • Elena Gonzalez Rodriguez and
  • Tinh-Hai Collet
  • + 5 authors

23 March 2021

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relations...

  • Article
  • Open Access
16 Citations
11,895 Views
9 Pages

23 March 2021

A possible role of dietary creatine for ensuring proper growth and development remains unknown. The main aim of this cross-sectional study was to quantify the amount of creatine consumed through regular diet among U.S. children and adolescents aged 2...

  • Review
  • Open Access
11 Citations
7,870 Views
14 Pages

Efficacy of Edible Bird’s Nest on Cognitive Functions in Experimental Animal Models: A Systematic Review

  • Maznah Ismail,
  • Abdulsamad Alsalahi,
  • Musheer Abdulwahid Aljaberi,
  • Ramlah Mohamad Ibrahim,
  • Faizah Abu Bakar and
  • Aini Ideris

23 March 2021

Edible bird’s nest (EBN) is constructed from saliva of swiftlets birds and consumed largely by Southeast and East Asians for its nutritional value and anti-aging properties. Although the neuroprotection of EBN in animals has been reported, there has...

  • Article
  • Open Access
17 Citations
4,303 Views
14 Pages

23 March 2021

Environmental factors, including nutritional habits or birth mode, are known key determinants for intestinal microbial composition. Investigations of the intestinal microbiome in different species in a multiplicity of studies during recent decades ha...

  • Article
  • Open Access
50 Citations
15,282 Views
21 Pages

23 March 2021

Breast cancer (BC) patients often ask for a healthy diet. Here, we investigated a healthy standard diet (SD), a low carb diet (LCD), and a ketogenic diet (KD) for BC patients during the rehabilitation phase. KOLIBRI was an open-label non-randomized o...

  • Article
  • Open Access
9 Citations
3,697 Views
14 Pages

Hypotensive and Hepatoprotective Properties of the Polysaccharide-Stabilized Foaming Composition Containing Hydrolysate of Whey Proteins

  • Alexandr G. Kruchinin,
  • Olga S. Savinova,
  • Olga A. Glazunova,
  • Konstantin V. Moiseenko,
  • Evgeniya Yu. Agarkova and
  • Tatyana V. Fedorova

23 March 2021

Whey protein hydrolysates (WPHs) are one of the most promising sources of biofunctional peptides with such beneficial properties as antioxidant, antihypertensive, anti-inflammatory and others. WPHs also could be used as foaming agents for aerated pro...

  • Article
  • Open Access
6 Citations
3,489 Views
19 Pages

Pathogenic Microenvironment from Diabetic–Obese Visceral and Subcutaneous Adipocytes Activating Differentiation of Human Healthy Preadipocytes Increases Intracellular Fat, Effect of the Apocarotenoid Crocetin

  • Lesgui Alviz,
  • David Tebar-García,
  • Raquel Lopez-Rosa,
  • Eva M. Galan-Moya,
  • Natalia Moratalla-López,
  • Gonzalo L. Alonso,
  • Eduardo Nava and
  • Sílvia Llorens

23 March 2021

In diabetes mellitus type 2 (DM2), developed obesity is referred to as diabesity. Implementation of a healthy diet, such as the Mediterranean, prevents diabesity. Saffron is frequently used in this diet because of its bioactive components, such as cr...

  • Article
  • Open Access
7 Citations
7,647 Views
12 Pages

Effects of a Short-Term “Fat Adaptation with Carbohydrate Restoration” Diet on Metabolic Responses and Exercise Performance in Well-Trained Runners

  • Kaixuan Che,
  • Junqiang Qiu,
  • Longyan Yi,
  • Menghui Zou,
  • Zhihui Li,
  • Amelia Carr,
  • Rhiannon M.J. Snipe and
  • Dan Benardot

23 March 2021

Periodized carbohydrate availability can enhance exercise capacity, but the effects of short-term fat adaptation carbohydrate restoration (FACR) diets on metabolic responses and exercise performance in endurance athletes have not been conclusively de...

  • Article
  • Open Access
10 Citations
4,291 Views
10 Pages

23 March 2021

Background: Diet has been associated with poor glycemic control in diabetes. Few studies have examined this association in people with type 1 diabetes (T1D), who are at a higher risk for cardiovascular disease than people without diabetes. Methods: W...

  • Article
  • Open Access
44 Citations
7,764 Views
13 Pages

Associations of Dietary Patterns with Incident Depression: The Maastricht Study

  • Vincenza Gianfredi,
  • Annemarie Koster,
  • Anna Odone,
  • Andrea Amerio,
  • Carlo Signorelli,
  • Nicolaas C. Schaper,
  • Hans Bosma,
  • Sebastian Köhler,
  • Pieter C. Dagnelie and
  • Simone J.P.M. Eussen
  • + 3 authors

23 March 2021

Our aim was to assess the association between a priori defined dietary patterns and incident depressive symptoms. We used data from The Maastricht Study, a population-based cohort study (n = 2646, mean (SD) age 59.9 (8.0) years, 49.5% women; 15,188 p...

  • Article
  • Open Access
10 Citations
4,521 Views
15 Pages

22 March 2021

Background: People with upper gastrointestinal cancer are at high risk for malnutrition without universal access to early nutrition interventions. Very little data exist on the attitudes and views of health professionals on providing nutrition care t...

  • Review
  • Open Access
37 Citations
9,437 Views
13 Pages

Obesity-Associated Inflammation: Does Curcumin Exert a Beneficial Role?

  • Rosaria Varì,
  • Beatrice Scazzocchio,
  • Annalisa Silenzi,
  • Claudio Giovannini and
  • Roberta Masella

22 March 2021

Curcumin is a lipophilic polyphenol, isolated from the plant turmeric of Curcuma longa. Curcuma longa has always been used in traditional medicine in Asian countries because it is believed to have numerous health benefits. Nowadays it is widely used...

  • Article
  • Open Access
8 Citations
4,038 Views
15 Pages

Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis

  • Dragana Arsenijevic,
  • Bojana Stojanovic,
  • Jelena Milovanovic,
  • Aleksandar Arsenijevic,
  • Milos Simic,
  • Marija Pergal,
  • Igor Kodranov,
  • Olga Cvetkovic,
  • Danilo Vojvodic and
  • Nebojsa Arsenijevic
  • + 3 authors

22 March 2021

The main biologically active components of plants belonging to the genus Allium, responsible for their biological activities, including anti-inflammatory, antioxidant and immunomodulatory, are organosulfur compounds. The aim of this study was to synt...

  • Article
  • Open Access
10 Citations
5,773 Views
10 Pages

Relationship between Vitamin Intake and Health-Related Quality of Life in a Japanese Population: A Cross-Sectional Analysis of the Shika Study

  • Nobuhiko Narukawa,
  • Hiromasa Tsujiguchi,
  • Akinori Hara,
  • Sakae Miyagi,
  • Takayuki Kannon,
  • Keita Suzuki,
  • Yukari Shimizu,
  • Thao Thi Thu Nguyen,
  • Kim Oanh Pham and
  • Hiroyuki Nakamura
  • + 15 authors

22 March 2021

Although epidemiological studies revealed a relationship between psychosocial states, such as depressive symptoms, and nutritional intake, limited information is currently available on vitamin intake. The Short Form-36 Health Survey (SF-36) is not li...

  • Article
  • Open Access
15 Citations
7,057 Views
16 Pages

22 March 2021

Small intestinal bacterial overgrowth (SIBO) occurs commonly, is difficult to treat, and frequently recurs. Bovine colostrum (BC) and chicken eggs contain immunoglobulins and other components that possess antimicrobial, immunoregulatory, and growth f...

  • Article
  • Open Access
32 Citations
13,562 Views
15 Pages

L-Glutamine Supplementation Enhances Strength and Power of Knee Muscles and Improves Glycemia Control and Plasma Redox Balance in Exercising Elderly Women

  • Gislene R. Amirato,
  • Juliana O. Borges,
  • Daniella L. Marques,
  • Juliana M. B. Santos,
  • Carlos A. F. Santos,
  • Marilia S. Andrade,
  • Guilherme E. Furtado,
  • Marcelo Rossi,
  • Lais N. Luis and
  • Tania C. Pithon-Curi
  • + 12 authors

22 March 2021

We investigated the effects of oral L-glutamine (Gln) supplementation, associated or not with physical exercises, in control of glycemia, oxidative stress, and strength/power of knee muscles in elderly women. Physically active (n = 21) and sedentary...

  • Review
  • Open Access
91 Citations
20,141 Views
32 Pages

Breast Milk: A Source of Functional Compounds with Potential Application in Nutrition and Therapy

  • Cristina Sánchez,
  • Luis Franco,
  • Patricia Regal,
  • Alexandre Lamas,
  • Alberto Cepeda and
  • Cristina Fente

22 March 2021

Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in its different stages of growth up to six months after birth. In addition, breastfeeding benefits both maternal and child health. Increasing knowledge has b...

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,597 Views
11 Pages

Home Artificial Nutrition in Polish Children: An Analysis of 9-Year National Healthcare Provider Data

  • Karolina Wyszomirska,
  • Adam Wyszomirski,
  • Michał Brzeziński,
  • Anna Borkowska,
  • Maciej Zagierski,
  • Jarosław Kierkuś,
  • Janusz Książyk,
  • Hanna Romanowska,
  • Magdalena Świder and
  • Agnieszka Szlagatys-Sidorkiewicz
  • + 1 author

21 March 2021

Background: Home artificial nutrition (HAN) is a developing method of treatment that reduces the need for hospitalizations. The epidemiology of pediatric HAN in Poland has not yet been covered in detail. This study is a longitudinal nationwide analys...

  • Article
  • Open Access
47 Citations
12,033 Views
12 Pages

Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study

  • Xiao-Qian Xie,
  • Yan Geng,
  • Qijie Guan,
  • Yilin Ren,
  • Lin Guo,
  • Qiqi Lv,
  • Zhen-Ming Lu,
  • Jin-Song Shi and
  • Zheng-Hong Xu

21 March 2021

Hericium erinaceus (H. erinaceus) is widely studied as a medicinal and edible fungus. Recent studies have shown that H. erinaceus has protective effects for diseases, such as inflammatory bowel disease and cancer, which are related to gut microbiota....

  • Review
  • Open Access
28 Citations
10,948 Views
14 Pages

Baby-Led Weaning: What Role Does It Play in Obesity Risk during the First Years? A Systematic Review

  • Nazareth Martinón-Torres,
  • Nathalie Carreira,
  • Rosaura Picáns-Leis,
  • Alexandra Pérez-Ferreirós,
  • Anton Kalén and
  • Rosaura Leis

21 March 2021

Childhood is a window of opportunity for the prevention of the obesity pandemic. Since “the first 1000 days of life” is a period in which healthy eating habits must be acquired, it should be the target for preventive strategies. Baby-led weaning (BLW...

  • Article
  • Open Access
14 Citations
6,871 Views
13 Pages

Prevalence of Anemia, Iron-Deficiency Anemia, and Associated Factors among Children Aged 1–5 Years in the Rural, Malaria-Endemic Setting of Popokabaka, Democratic Republic of Congo: A Cross-Sectional Study

  • Branly Kilola Mbunga,
  • Mala Ali Mapatano,
  • Tor A. Strand,
  • Elin Lovise F. Gjengedal,
  • Pierre Zalagile Akilimali and
  • Ingunn Marie S. Engebretsen

21 March 2021

Iron deficiency (ID), the leading cause of anemia and the most common nutritional deficiency globally, is not well reported among children in malaria-endemic settings, and little is known about its contribution to anemia in these settings. We aimed t...

  • Feature Paper
  • Review
  • Open Access
22 Citations
5,935 Views
15 Pages

Evidence of a Positive Link between Consumption and Supplementation of Ascorbic Acid and Bone Mineral Density

  • Mariangela Rondanelli,
  • Gabriella Peroni,
  • Federica Fossari,
  • Viviana Vecchio,
  • Milena Anna Faliva,
  • Maurizio Naso,
  • Simone Perna,
  • Enrica Di Paolo,
  • Antonella Riva and
  • Alice Tartara
  • + 2 authors

21 March 2021

In animal models it has been shown that ascorbic acid (AA) is an essential cofactor for the hydroxylation of proline in collagen synthesis. However, there are still no precise indications regarding the role of AA in maintaining bone health in humans,...

  • Article
  • Open Access
31 Citations
8,709 Views
18 Pages

The Relationship between Low Serum Vitamin D Levels and Altered Intestinal Barrier Function in Patients with IBS Diarrhoea Undergoing a Long-Term Low-FODMAP Diet: Novel Observations from a Clinical Trial

  • Michele Linsalata,
  • Giuseppe Riezzo,
  • Antonella Orlando,
  • Benedetta D’Attoma,
  • Laura Prospero,
  • Valeria Tutino,
  • Maria Notarnicola and
  • Francesco Russo

21 March 2021

Decreased serum vitamin D (VD) levels have been associated with gastrointestinal (GI) disorders, including irritable bowel syndrome (IBS). VD can also modulate the intestinal barrier. Given the link between the GI barrier’s alterations and diet, atte...

  • Article
  • Open Access
37 Citations
6,577 Views
11 Pages

Characterization of Gut Microbiome in Korean Patients with Metabolic Associated Fatty Liver Disease

  • Joo Hyun Oh,
  • Je Hee Lee,
  • Min Seok Cho,
  • Hyeree Kim,
  • Jongsik Chun,
  • Joon Hyeok Lee,
  • Yeup Yoon and
  • Wonseok Kang

21 March 2021

Metabolic associated fatty liver disease (MAFLD) is a new concept where the presence of both fatty liver and metabolic abnormality are necessary for diagnosis. Several studies have reported that altered gut microbiome is closely associated with metab...

  • Article
  • Open Access
2 Citations
3,658 Views
11 Pages

21 March 2021

Current strategies targeting serum cholesterol bring limited benefits to mortality and macrovascular events prevention among hemodialysis patients. Direct measurements and analysis on circulating markers of cholesterol homeostasis could be promising...

  • Review
  • Open Access
27 Citations
6,660 Views
19 Pages

Vitamin D and Allergy Susceptibility during Gestation and Early Life

  • Daniela Briceno Noriega and
  • Huub F. J. Savelkoul

21 March 2021

Worldwide, the prevalence of allergies in young children, but also vitamin D deficiency during pregnancy and in newborns is rising. Vitamin D modulates the development and activity of the immune system and a low vitamin D status during pregnancy and...

  • Feature Paper
  • Review
  • Open Access
37 Citations
10,923 Views
22 Pages

Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights

  • María Jesús Rodríguez-Sojo,
  • Antonio Jesús Ruiz-Malagón,
  • María Elena Rodríguez-Cabezas,
  • Julio Gálvez and
  • Alba Rodríguez-Nogales

21 March 2021

Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and mo...

  • Article
  • Open Access
50 Citations
7,914 Views
23 Pages

21 March 2021

The incidence of obesity, which is closely associated with the gut microbiota and chronic inflammation, has rapidly increased in the past 40 years. Therefore, the probiotic-based modification of the intestinal microbiota composition has been develope...

  • Feature Paper
  • Review
  • Open Access
66 Citations
16,350 Views
33 Pages

The Gut-Liver Axis in Cholestatic Liver Diseases

  • Andreas Blesl and
  • Vanessa Stadlbauer

21 March 2021

The gut-liver axis describes the physiological interplay between the gut and the liver and has important implications for the maintenance of health. Disruptions of this equilibrium are an important factor in the evolution and progression of many live...

  • Review
  • Open Access
27 Citations
27,409 Views
56 Pages

Paleolithic Diet—Effect on the Health Status and Performance of Athletes?

  • Barbara Frączek,
  • Aleksandra Pięta,
  • Adrian Burda,
  • Paulina Mazur-Kurach and
  • Florentyna Tyrała

21 March 2021

The aim of this meta-analysis was to review the impact of a Paleolithic diet (PD) on selected health indicators (body composition, lipid profile, blood pressure, and carbohydrate metabolism) in the short and long term of nutrition intervention in hea...

  • Review
  • Open Access
37 Citations
12,432 Views
10 Pages

Ketogenic Diet as a Preventive and Supportive Care for COVID-19 Patients

  • Elena Gangitano,
  • Rossella Tozzi,
  • Orietta Gandini,
  • Mikiko Watanabe,
  • Sabrina Basciani,
  • Stefania Mariani,
  • Andrea Lenzi,
  • Lucio Gnessi and
  • Carla Lubrano

20 March 2021

Severe obesity is associated with an increased risk of admission to intensive care units and need for invasive mechanical ventilation in patients with COVID-19. The association of obesity and COVID-19 prognosis may be related to many different factor...

  • Article
  • Open Access
14 Citations
4,101 Views
20 Pages

Bone Mineral Density, Body Composition, and Metabolic Health of Very Low Birth Weight Infants Fed in Hospital Following Current Macronutrient Recommendations during the First 3 Years of Life

  • Walter Mihatsch,
  • Izaskun Dorronsoro Martín,
  • Vicente Barrios-Sabador,
  • María L. Couce,
  • Gabriel Á. Martos-Moreno,
  • Jesús Argente,
  • José Quero and
  • Miguel Saenz de Pipaon

20 March 2021

The present study longitudinally evaluated growth, bone mineral density, body composition, and metabolic health outcome in very low birth weight (VLBW) infants whose in-hospital target nutrient intake was within recent recommendations. From six month...

  • Article
  • Open Access
14 Citations
3,712 Views
11 Pages

20 March 2021

The aim was to investigate the protein knowledge of community-dwelling older adults. A survey was conducted among 1825 adults aged ≥65 years and living in Finland, Netherlands, Poland, Spain and United Kingdom in 2017. Protein knowledge was measured...

  • Article
  • Open Access
9 Citations
3,159 Views
13 Pages

Modification of the Lipid Profile of the Initial Oral Biofilm In Situ Using Linseed Oil as Mouthwash

  • Anna Kensche,
  • Marco Reich,
  • Christian Hannig,
  • Klaus Kümmerer and
  • Matthias Hannig

19 March 2021

Lipids are of interest for the targeted modification of oral bioadhesion processes. Therefore, the sustainable effects of linseed oil on the composition and ultrastructure of the in situ pellicle were investigated. Unlike saliva, linseed oil contains...

  • Article
  • Open Access
50 Citations
7,286 Views
15 Pages

The Relationship between Restrained Eating, Body Image, and Dietary Intake among University Students in China: A Cross-Sectional Study

  • Cuiting Yong,
  • Hanmei Liu,
  • Qiping Yang,
  • Jing Luo,
  • Yufeng Ouyang,
  • Minghui Sun,
  • Yue Xi,
  • Caihong Xiang and
  • Qian Lin

19 March 2021

This study aims to explore the association between restrained eating, body image, and dietary intake among Chinese college students. This cross-sectional study included 1301 college students at two universities in Hunan Province. Electronic questionn...

  • Article
  • Open Access
21 Citations
8,651 Views
14 Pages

19 March 2021

Salicylic acid and its derivatives (including acetylsalicylic acid/aspirin) are popular in medicine. They also occur naturally in many food products. The aim of the study was to investigate the effect of the personalized low salicylate diet (PLSD) on...

  • Article
  • Open Access
37 Citations
4,811 Views
18 Pages

Selection of Gut-Resistant Bacteria and Construction of Microbial Consortia for Improving Gluten Digestion under Simulated Gastrointestinal Conditions

  • Maria De Angelis,
  • Sonya Siragusa,
  • Mirco Vacca,
  • Raffaella Di Cagno,
  • Fernanda Cristofori,
  • Michael Schwarm,
  • Stefan Pelzer,
  • Monika Flügel,
  • Bodo Speckmann and
  • Marco Gobbetti
  • + 1 author

19 March 2021

This work aimed to define the microbial consortia that are able to digest gluten into non-toxic and non-immunogenic peptides in the human gastrointestinal tract. Methods: 131 out of 504 tested Bacillus and lactic acid bacteria, specifically Bacillus...

  • Article
  • Open Access
12 Citations
3,863 Views
12 Pages

Role of HO-1 against Saturated Fatty Acid-Induced Oxidative Stress in Hepatocytes

  • Noriyoshi Ogino,
  • Koichiro Miyagawa,
  • Kenjiro Nagaoka,
  • Yuki Matsuura-Harada,
  • Shihona Ogino,
  • Masashi Kusanaga,
  • Shinji Oe,
  • Yuichi Honma,
  • Masaru Harada and
  • Keiki Ogino
  • + 2 authors

19 March 2021

Increased circulating levels of free fatty acids, especially saturated ones, are involved in disease progression in the non-alcoholic fatty liver. Although the mechanism of saturated fatty acid-induced toxicity in the liver is not fully understood, o...

  • Article
  • Open Access
2 Citations
14,603 Views
12 Pages

19 March 2021

INTRICATE is a prospective double-blind placebo-controlled feasibility study, assessing the influence of combined vitamin K2 and vitamin D3 supplementation on micro-calcification in carotid artery disease as imaged by hybrid Sodium [18F]Fluoride (Na[...

  • Article
  • Open Access
26 Citations
5,286 Views
11 Pages

High Adherence to the Mediterranean Diet Is Associated with a Reduced Risk of Obesity among Adults in Gulf Countries

  • Israa M. Shatwan,
  • Eiman A. Alhinai,
  • Balqees Alawadhi,
  • Shelini Surendran,
  • Najlaa M. Aljefree and
  • Noha M. Almoraie

19 March 2021

The Mediterranean diet (MedDiet) is considered as a good example of a healthy dietary pattern that has protective effects on obesity. The aim of the present study was to assess the adherence of adults from three Gulf countries (Saudi Arabia, Oman, an...

  • Article
  • Open Access
13 Citations
3,090 Views
11 Pages

Intrauterine Transfer of Polyunsaturated Fatty Acids in Mother–Infant Dyads as Analyzed at Time of Delivery

  • Vanessa Woodard,
  • Melissa Thoene,
  • Matthew Van Ormer,
  • Maranda Thompson,
  • Corrine Hanson,
  • Sathish Kumar Natarajan,
  • Maheswari Mukherjee,
  • Ana Yuil-Valdes,
  • Tara M. Nordgren and
  • Ann Anderson-Berry
  • + 2 authors

19 March 2021

Polyunsaturated fatty acids (PUFAs) are essential for fetal development, and intrauterine transfer is the only supply of PUFAs to the fetus. The prevailing theory of gestational nutrient transfer is that certain nutrients (including PUFAs) may have p...

  • Article
  • Open Access
33 Citations
6,086 Views
15 Pages

Comparison of Indices of Carbohydrate Quality and Food Sources of Dietary Fiber on Longitudinal Changes in Waist Circumference in the Framingham Offspring Cohort

  • Caleigh M. Sawicki,
  • Alice H. Lichtenstein,
  • Gail T. Rogers,
  • Paul F. Jacques,
  • Jiantao Ma,
  • Edward Saltzman and
  • Nicola M. McKeown

19 March 2021

The long-term impact of carbohydrate quality on abdominal weight gain is not fully understood. We aimed to examine the prospective relation of a carbohydrate quality index (CQI; defined by four criteria: dietary fiber, glycemic index, whole grain-to-...

  • Article
  • Open Access
15 Citations
3,863 Views
11 Pages

Nutraceutical Screening in a Zebrafish Model of Muscular Dystrophy: Gingerol as a Possible Food Aid

  • Rosario Licitra,
  • Maria Marchese,
  • Letizia Brogi,
  • Baldassare Fronte,
  • Letizia Pitto and
  • Filippo M. Santorelli

19 March 2021

Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is an inherited neuromuscular disorder that causes loss of muscle mass and motor skills. In the era of genomic medicine, there is still no known cure for DMD. In clinical...

  • Article
  • Open Access
32 Citations
13,131 Views
12 Pages

Efficacy of a Low-Dose Diosmin Therapy on Improving Symptoms and Quality of Life in Patients with Chronic Venous Disease: Randomized, Double-Blind, Placebo-Controlled Trial

  • Raffaele Serra,
  • Nicola Ielapi,
  • Andrea Bitonti,
  • Stefano Candido,
  • Salvatore Fregola,
  • Alessandro Gallo,
  • Antonio Loria,
  • Lucia Muraca,
  • Luca Raimondo and
  • Luca Gallelli
  • + 2 authors

19 March 2021

Chronic Venous Disease (CVD) is a common medical condition affecting up to 80% of the general population. Clinical manifestations can range from mild to more severe signs and symptoms that contribute to the impairment of the quality of life (QoL) of...

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Nutrients - ISSN 2072-6643