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Viruses, Volume 17, Issue 7

July 2025 - 153 articles

Cover Story: Mother-to-child transmission of HIV-1 and pediatric ART may influence virologic and immune features, resulting in differences in the infected cell populations that persist compared to adults who acquire HIV-1. Using long-amplicon proviral sequencing, we investigated the characteristics of proviruses that persisted in five children for 7–9 years on ART. We found fewer intact proviruses, fewer mutations in the major splice donor (MSD) site, and a higher proportion of proviruses with defective tat compared to adults on long-term ART. Our results suggest that immune and ART pressures may shape a qualitatively different HIV proviral landscape in children that may influence targets for measuring and eliminating the HIV reservoir and achieving remission without ART. View this paper
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Articles (153)

  • Article
  • Open Access
2,222 Views
12 Pages

Genomic Epidemiology of SARS-CoV-2 in Ukraine from May 2022 to March 2024 Reveals Omicron Variant Dynamics

  • Anna Iaruchyk,
  • Jason Farlow,
  • Artem Skrypnyk,
  • Serhii Matchyshyn,
  • Alina Kovalchuk,
  • Iryna Demchyshyna,
  • Mykhailo Rosada,
  • Aron Kassahun Aregay and
  • Jarno Habicht

17 July 2025

In Ukraine, SARS-CoV-2 detection and national genomic surveillance have been complicated by full-scale war, limited resources, and varying levels of public health infrastructure impacted across the country. Following the Spring of 2022, only a paucit...

  • Article
  • Open Access
1,310 Views
16 Pages

A More Rapid Method for Culturing LUHMES-Derived Neurons Provides Greater Cell Numbers and Facilitates Studies of Multiple Viruses

  • Adam W. Whisnant,
  • Stephanie E. Clark,
  • José Alberto Aguilar-Briseño,
  • Lorellin A. Durnell,
  • Arnhild Grothey,
  • Ann M. Miller,
  • Steven M. Varga,
  • Jeffery L. Meier,
  • Charles Grose and
  • Patrick L. Sinn
  • + 5 authors

16 July 2025

The ability to study mature neuronal cells ex vivo is complicated by their non-dividing nature and difficulty in obtaining large numbers of primary cells from organisms. Thus, numerous transformed progenitor models have been developed that can be rou...

  • Article
  • Open Access
1,251 Views
13 Pages

Seroprevalence of Equine Influenza Virus Antibodies in Horses from Four Localities in Colombia

  • Juliana Gonzalez-Obando,
  • Jeiczon Jaimes-Dueñez,
  • Angélica Zuluaga-Cabrera,
  • Jorge E. Forero,
  • Andrés Diaz,
  • Carlos Rojas-Arbeláez and
  • Julian Ruiz-Saenz

16 July 2025

Equine influenza is a highly contagious disease caused by the equine influenza virus (EIV). The occurrence of EIV outbreaks in America is associated with low levels of vaccination coverage. In Colombia, no seroprevalence evaluation has been carried o...

  • Review
  • Open Access
1,133 Views
14 Pages

Spatiotemporal Distribution and Risk Factors of African Swine Fever Outbreak Cases in Uganda for the Period 2010–2023

  • Eddie M. Wampande,
  • Robert Opio,
  • Simon P. Angeki,
  • Corrie Brown,
  • Bonto Faburay,
  • Rose O. Ademun,
  • Kenneth Ssekatawa,
  • David D. South,
  • Charles Waiswa and
  • Peter Waiswa

16 July 2025

This paper describes the spatiotemporal distribution and risk factors of African Swine Fever (ASF) in Uganda for the period of 2010 through 2023. The study utilized a comprehensive dataset from monthly reports (2010–2023) from District Veterina...

  • Article
  • Open Access
734 Views
17 Pages

Biological, Molecular, and Physiological Characterization of Four Soybean Mosaic Virus Isolates Present in Argentine Soybean Crops

  • Mariel Maugeri,
  • Marianela Rodríguez,
  • Nicolas Bejerman,
  • Irma G. Laguna and
  • Patricia Rodríguez Pardina

16 July 2025

Soybean mosaic virus (SMV) causes systemic infections in soybean plants, leading to chlorotic mosaic and significant yield losses. In Argentina, during the 1990s, three isolates were collected in Marcos Juárez (MJ), Manfredi (M), and Northwest...

  • Article
  • Open Access
656 Views
10 Pages

Soluble Neuropilin-1 as a Marker for Distinguishing Bacterial and Viral Sepsis in Critically Ill Patients—A Prospective, Multicenter, Observational Study

  • Fabian Perschinka,
  • Georg Franz Lehner,
  • Timo Mayerhöfer,
  • Frank Hartig,
  • Birgit Zassler,
  • Johannes Bösch,
  • Dietmar Fries,
  • Romuald Bellmann and
  • Michael Joannidis

16 July 2025

Sepsis causes millions of deaths each year. Rapid, targeted therapy can reduce mortality rates. Both bacterial and viral pathogens can trigger sepsis, but the utility of commonly used inflammatory markers for differentiation remains controversial. Mo...

  • Article
  • Open Access
1,226 Views
27 Pages

Characterization of a STAT-1 Knockout Mouse Model for Machupo Virus Infection and Pathogenesis

  • Stephanie R. Monticelli,
  • Ana I. Kuehne,
  • Russell R. Bakken,
  • Susan R. Coyne,
  • Kenise D. Lewis,
  • Jo Lynne W. Raymond,
  • Xiankun Zeng,
  • Joshua B. Richardson,
  • Zebulon Lapoint and
  • Jennifer L. Williams
  • + 4 authors

16 July 2025

Machupo virus (MACV), a member of the Arenaviridae family and causative agent of Bolivian hemorrhagic fever, results in lethality rates of 25–35% in humans. Mice lacking the signal transducer and activator of transcription 1 (STAT-1−/&min...

  • Article
  • Open Access
731 Views
16 Pages

The Cytoplasmic Tail of Ovine Herpesvirus 2 Glycoprotein B Affects Cell Surface Expression and Is Required for Membrane Fusion

  • Colleen M. Lynch,
  • Maria K. Herndon,
  • McKenna A. Hull,
  • Daniela D. Moré,
  • Katherine N. Baker,
  • Cristina W. Cunha and
  • Anthony V. Nicola

16 July 2025

Ovine herpesvirus 2 (OvHV-2) causes the fatal veterinary disease malignant catarrhal fever (MCF). Fusion is an essential step in the host cell entry of enveloped viruses and is an important target for vaccine development. OvHV-2 cannot be propagated...

  • Article
  • Open Access
950 Views
14 Pages

16 July 2025

Long-acting (LA) antiretroviral therapies for human immunodeficiency virus (HIV), such as injectable formulations of cabotegravir and rilpivirine (CAB+RPV LA), are now available. Considering the limited data on the out-of-hospital administration of t...

  • Retraction
  • Open Access
805 Views
1 Page

RETRACTED: Branda et al. Zoonotic Paramyxoviruses: Evolution, Ecology, and Public Health Strategies in a Changing World. Viruses 2024, 16, 1688

  • Francesco Branda,
  • Grazia Pavia,
  • Alessandra Ciccozzi,
  • Angela Quirino,
  • Nadia Marascio,
  • Giovanni Matera,
  • Chiara Romano,
  • Chiara Locci,
  • Ilenia Azzena and
  • Noemi Pascale
  • + 5 authors

16 July 2025

The journal retracts the article “Zoonotic Paramyxoviruses: Evolution, Ecology, and Public Health Strategies in a Changing World” [...]

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Viruses - ISSN 1999-4915