Thoracic Oncology: Current Challenges and Future Prospects

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Oncology".

Deadline for manuscript submissions: 25 August 2026 | Viewed by 28

Special Issue Editors


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Guest Editor
1. Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy
2. Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy
Interests: lung cancer; thoracic surgery; thoracic oncology
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Guest Editor Assistant
Department of Thoracic Surgery, European Institute of Oncology (IEO) IRCCS, 20141 Milan, Italy
Interests: lung cancer; AI; immuno-oncology; thoracic surgery; cythopathology; global health

Special Issue Information

Dear Colleagues,

Thoracic oncology has witnessed remarkable changes as a result of advances in molecular biology, imaging technologies, personalized medicine, and minimally invasive surgery.

Thoracic malignancies, including lung cancer, mesothelioma, and mediastinal tumors, remain a substantial global health burden characterized by high incidence, late-stage diagnosis, and differential response to therapy, despite significant advances. While we are in a unique, unprecedented period of new therapies and treatment approach development, there are still multiple clinical and scientific barriers to overcome before we can achieve the genuine success of our treatment methods, including early detection, treatment resistance, best patient selection, and long-term results.

This Special Issue, titled Thoracic Oncology: Current Challenges and Future Prospects, will provide an updated overview of the current state of the art in thoracic oncology, as well as outline unmet needs and potential pathways for future research. Novel subjects include screening and early detection, biomarkers, immunotherapy and targeted therapies, perioperative treatment, "thoracic" surgery, oligometastatic disease, and multimodality therapy. Special emphasis will be dedicated to translational research, such as liquid biopsy, radiogenomics, tumor microenvironment profiling, and artificial intelligence for prediction, classification, and decision making.

The best submissions addressing mechanisms of resistance, minimal residual disease, quality-of-life and patient-reported outcomes should be at the cutting edge of research. We are also interested in novel surgical technologies that include, but are not limited to, robotic and image-guided surgical procedures.

We invite original research articles, clinical studies, systematic reviews and meta-analyses, translational studies, and high-quality narrative reviews. We also encourage multidisciplinary contributions spanning thoracic surgery, oncology, radiology, pathology, molecular science, and computational medicine.

Dr. Luca Bertolaccini
Guest Editor

Dr. Claudia Bardoni
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • thoracic oncology
  • lung cancer
  • mesothelioma
  • mediastinal tumors
  • immunotherapy
  • artificial intelligence
  • targeted therapy
  • screening
  • early detection
  • biomarkers
  • liquid biopsy
  • radiomics
  • radiogenomics
  • robotic surgery
  • multimodality treatment
  • oligometastatic disease
  • tumor microenvironment

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This special issue is now open for submission.
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