Pharmaceuticals, Volume 12, Issue 4 (December 2019) – 46 articles
Cover Story (view full-size image): Among the known metal-containing drugs, ruthenium(III) complexes have emerged for their promising anti-cancer properties, leading to a few candidates in advanced clinical trials. This review highlights the unique role of Ru(III)-complexes in the current panorama of anticancer agents, with particular emphasis on Ru-containing nanoformulations that incorporate the Ru(III) complexes into suitable nanocarriers enabling improved bioavailability and pharmacokinetic properties. Preclinical evaluation of these nanoaggregates is discussed with a special focus on the investigation of their mechanism of action at a molecular level, highlighting their pharmacological potential in tumor disease models and value for biomedical applications. View this paper
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.