Molbank, Volume 2009, Issue 3

Abstract: A new flavonoid glycoside (1) has been isolated from the aerial parts of Salix denticulata (Salicaceae) together with five known compounds, β-sitosterol, 2,6-dihydroxy- 4-methoxy acetophenone, eugenol-1-O-β-D-glucopyranoside, 1-O-β-D-(3’-be...

This present work aims at synthesizing a novel tetrazole from phenothiazine. Phenothiazine is converted into a nitrile by reacting it with 4-hydroxybenzaldehyde, sodium metabisulphite and sodium cyanide. The nitrile on treatment with NaN₃/DMF yielded...

Reaction of 5-chloro-1,3-dimethyl-1H-pyrazole with I₂/HIO₃ in refluxing acetic acid gives the title compound in good yield. Detailed spectroscopic data (¹H NMR, ¹³C NMR, ¹⁵N NMR, IR, MS) are presented.

The regioselective alkylation of an oxonaphthalene-annelated pyrrole system is reported. The regioselectivity of alkylation can be controlled by the selection of the solvent.

Quinolinyl amines are important organic compounds which possess a variety of pharmacological activities such as antimalarial, antifungal, hypotensive and antidepressant activity.

This paper describes the synthesis of 3-methyl-1-morpholin-4-ylmethyl-2,6-diphenylpiperidin-4-one from 3-methyl-2,6-diphenylpiperidin-4-one. The synthesized compound was characterized by FT-IR, ¹H NMR, EI-MS and elemental analysis.

16-Dehydropregnenolone acetate (16-DPA) (1), an exocyclic α,β-conjugated ketone having a steroidal skeleton, when treated with mercuric(II) acetate in acetic acid furnished a single compound identified as (2). The structure of compound (2) has been e...

A new compound, 4,6-diamino-5-[4-(dimethylamino)benzylidene]pyrimidin-2(5H)-one, was synthesized and its IR, ¹H NMR and ¹³C NMR and MS spectroscopic data are presented.

A simple method for the synthesis of pyrazoline derivative containing furan moiety was developed. Thus, 5-(6-bromo-1,3-benzodioxol-5-yl)-3-(2-furyl)-1-(3-methyl-phenyl)-4,5-dihydro-1H-pyrazole was synthesized using microwave irradiation and it was ch...

Reaction of dibenzalacetone with hydrazine hydrate and formic acid yielded a novel 2-pyrazoline 1, characterized by ESI-MS, FT-IR, UV, ¹HNMR and ¹³CNMR data and microanalysis.

The synthesis of bis (1-methyl-2-octynyl) ether using two secondary alcohols under Nicholas reaction conditions is reported. The reaction is possible due to a catalytic participation of the Lewis acid when the nucleophilic alcohol is protected as a T...

2-(4-Pentyloxyphenyl)benzothiazole was synthesized and its IR, ¹H NMR and MS spectroscopic data are presented.

A new Schiff base ester comprising of heterocyclic moiety, 3-hydroxy-4-{[(6-methoxy-1,3-benzothiazol-2-yl)imino]methyl}phenyl palmitate was synthesized and its IR, ¹H NMR, ¹³C NMR, elemental analysis and MS spectroscopic data are presented.

A new 2-(4-propyloxyphenyl)benzothiazole was synthesized and its IR, ¹H and ¹³C NMR and MS spectroscopic data are presented.

2-(4-Heptyloxyphenyl)benzothiazole was synthesized and its IR, ¹H NMR and MS spectroscopic data are presented.

The title compound was synthesized by N-alkylation of 4-(4-chlorophenyl)piperazine with ethyl 2-bromo-2-methylpropanoate and its IR, ¹H NMR, ¹³C NMR and Mass spectroscopic data are reported.

A new heterocycle 2-(3-methoxy-4-hexadecanoyloxyphenyl)benzothiazole was synthesized and its IR, ¹H NMR, ¹³C NMR and MS spectroscopic data are presented.

The reaction of 1-phenyl-3-trifluoromethyl-2-pyrazolin-5-one and 2-chlorobenzaldehyde leads to the title compound, which results from addition of a second pyrazolone unit to the primarily formed 1:1 condensation product. Detailed spectroscopic data (...

(E)-2,4-Dinitro-N-((2E,4E)-4-phenyl-5-(pyrrolidin-1-yl)penta-2,4-dienylidene) aniline dye was prepared in one pot by reaction of premade N-2,4-dinitrophenyl-3-phenylpyridinium chloride (DNPPC) and pyrrolidine in absolute MeOH.

The reaction of 3-methyl-1-phenyl-2-pyrazolin-5-one and 2-bromo-3-furoyl chloride in the presence of Ca(OH)₂ in 1,4-dioxane gave the title compound. The latter was also obtained in much higher yield upon reaction of the starting materials in the syst...

The preparation of 5-bromo-2-naphthol (4) in three steps from 5-amino-2-naphthol (1) is described. A sulfonic acid group is introduced at the 1-position as an activating and protecting group for the Sandmeyer reaction. The sulfonate group allows for...