You are currently on the new version of our website. Access the old version .

Molecules, Volume 23, Issue 8

August 2018 - 252 articles

Cover Story: A viral protein R-derived 7-mer peptide with photo-reactive benzoylphenylalanyl and biotin residues that exhibits low micromolar HIV-1 integrase (IN) inhibitory potency, was shown to bind directly to IN during photo-crosslinking experiments. The peptide does not interfere with IN–DNA interactions or induce higher-order aberrant IN multimerization, suggesting a mode of action distinct from clinically used integrase strand transfer inhibitors (INSTIs) and experimental allosteric IN inhibitors. This pharmacological tool may aid identifying a site for therapeutic development. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (252)

  • Article
  • Open Access
69 Citations
7,641 Views
12 Pages

Antimicrobial Properties of Spent Hops Extracts, Flavonoids Isolated Therefrom, and Their Derivatives

  • Agnieszka Bartmańska,
  • Ewa Wałecka-Zacharska,
  • Tomasz Tronina,
  • Jarosław Popłoński,
  • Sandra Sordon,
  • Ewa Brzezowska,
  • Jacek Bania and
  • Ewa Huszcza

17 August 2018

Hop cones preparations possess a wide range of biological activities including antimicrobial properties. In this work, we evaluated the effect of various organic extracts obtained from spent hops, as well as six hops flavonoids and their twenty natur...

  • Review
  • Open Access
6 Citations
4,828 Views
13 Pages

Turning Stem Cells Bad: Generation of Clinically Relevant Models of Human Acute Myeloid Leukemia through Gene Delivery- or Genome Editing-Based Approaches

  • Maria Mesuraca,
  • Nicola Amodio,
  • Emanuela Chiarella,
  • Stefania Scicchitano,
  • Annamaria Aloisio,
  • Bruna Codispoti,
  • Valeria Lucchino,
  • Ylenia Montalcini,
  • Heather M. Bond and
  • Giovanni Morrone

17 August 2018

Acute myeloid leukemia (AML), the most common acute leukemia in the adult, is believed to arise as a consequence of multiple molecular events that confer on primitive hematopoietic progenitors unlimited self-renewal potential and cause defective diff...

  • Article
  • Open Access
13 Citations
5,972 Views
12 Pages

Aromatic Thioacetal-Bridged ROS-Responsive Nanoparticles as Novel Gene Delivery Vehicles

  • Guo-Qing Lin,
  • Wen-Jing Yi,
  • Qiang Liu,
  • Xue-Jun Yang and
  • Zhi-Gang Zhao

17 August 2018

In this report, a series of polycations are designed and synthesized by conjugating reactive oxygen species (ROS)-responsive thioacetal-linkers to low molecular weight (LMW) polyethylenimine (PEI) via ring-opening polymerization. Their structure&ndas...

  • Article
  • Open Access
41 Citations
9,189 Views
14 Pages

Effect of Volatile Organic Chemicals in Chrysanthemum indicum Linné on Blood Pressure and Electroencephalogram

  • Da-Som Kim,
  • Young-Min Goo,
  • Jinju Cho,
  • Jookyeong Lee,
  • Dong Yeol Lee,
  • Seung Mi Sin,
  • Young Sook Kil,
  • Won Min Jeong,
  • Keon Hee Ko and
  • Ki Jeung Yang
  • + 6 authors

17 August 2018

This study identified the volatile organic compounds in the essential oils that are extracted from Chrysanthemum indicum Linné (C. indicum Linné) and investigated the effects of the inhalation of these compounds. We detected a total of...

  • Review
  • Open Access
63 Citations
10,794 Views
22 Pages

Gelatin as a Photosensitive Material

  • Sergio Calixto,
  • Nina Ganzherli,
  • Sergey Gulyaev and
  • Susana Figueroa-Gerstenmaier

17 August 2018

Because this issue journal is dedicated to Gelatin, here we present a few applications of gelatin in the field of optics. Optics is the science that studies the production, propagation, interaction and detection of light. Various materials sensitive...

  • Article
  • Open Access
54 Citations
8,674 Views
13 Pages

UPLC-QTOF/MS-Based Metabolomics Applied for the Quality Evaluation of Four Processed Panax ginseng Products

  • Jae Won Lee,
  • Seung-Heon Ji,
  • Bo-Ram Choi,
  • Doo Jin Choi,
  • Yeong-Geun Lee,
  • Hyoung-Geun Kim,
  • Geum-Soog Kim,
  • Kyuil Kim,
  • Youn-Hyung Lee and
  • Nam-In Baek
  • + 1 author

17 August 2018

In the food industry and herbal markets, it is critical to control the quality of processed Panax ginseng products. In this study, ultra-performance liquid chromatography coupled to quadrupole time of flight mass spectrometry (UPLC-QTOF/MS)-based met...

  • Article
  • Open Access
187 Citations
14,899 Views
11 Pages

Two Classes of Pigments, Carotenoids and C-Phycocyanin, in Spirulina Powder and Their Antioxidant Activities

  • Woo Sung Park,
  • Hye-Jin Kim,
  • Min Li,
  • Dong Hoon Lim,
  • Jungmin Kim,
  • Sang-Soo Kwak,
  • Chang-Min Kang,
  • Mario G. Ferruzzi and
  • Mi-Jeong Ahn

17 August 2018

Arthrospira platensis is the widely available source of spirulina that contains distinctive natural pigments, including carotenoids and C-phycocyanin (C-PC). In this study, the major carotenoid and C-PC contents were determined in seven commercially...

  • Article
  • Open Access
55 Citations
7,851 Views
25 Pages

A Polyphenol Rich Extract from Solanum melongena L. DR2 Peel Exhibits Antioxidant Properties and Anti-Herpes Simplex Virus Type 1 Activity In Vitro

  • Antonella Di Sotto,
  • Silvia Di Giacomo,
  • Donatella Amatore,
  • Marcello Locatelli,
  • Annabella Vitalone,
  • Chiara Toniolo,
  • Giuseppe Leonardo Rotino,
  • Roberto Lo Scalzo,
  • Anna Teresa Palamara and
  • Maria Elena Marcocci
  • + 1 author

17 August 2018

DR2B and DR2C extracts, obtained by ethanolic maceration of peel from commercially and physiologically ripe aubergine berries, were studied for the antioxidative cytoprotective properties and anti-HSV-1 activity, in line with the evidence that severa...

  • Article
  • Open Access
19 Citations
6,966 Views
16 Pages

Synthesis, Spectroscopic Analysis and Assessment of the Biological Activity of New Hydrazine and Hydrazide Derivatives of 3-Formylchromone

  • Krzysztof Słomiak,
  • Andrzej Łazarenkow,
  • Lilianna Chęcińska,
  • Joachim Kusz,
  • Justyn Ochocki and
  • Jolanta Nawrot-Modranka

17 August 2018

The hydrazine and hydrazide derivatives of benzo-γ-pyrones with fluorine substituents remain an unexplored group of chemical compounds. This preliminary study reports the synthesis, structural assessment, initial microbiological screening and b...

  • Article
  • Open Access
15 Citations
6,062 Views
14 Pages

Beneficial Effect of Herbal Formulation KM1608 on Inflammatory Bowl Diseases: A Preliminary Experimental Study

  • Myoung-Sook Shin,
  • Sang-Back Kim,
  • Jaemin Lee,
  • Han-Seok Choi,
  • Jimin Park,
  • Jun Yeon Park,
  • Sullim Lee,
  • Gwi Seo Hwang,
  • Bon Am Koo and
  • Ki Sung Kang

17 August 2018

Aucklandia lappa DC., Terminalia chebula Retz and Zingiber officinale Roscoe have been traditionally used in east Asia to treat chronic diarrhea and abdominal pain. This study aimed to evaluated the anti-inflammatory activity of KM1608, which is comp...

of 26

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Molecules - ISSN 1420-3049