Special Issue "Natural Active Agents Against Bacteria, Fungi and Parasites"
Deadline for manuscript submissions: 31 December 2019
Prof. Dr. Maria Daglia
Department of Drug Sciences, University of Pavia, Italy
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Interests: food chemistry and analysis; food supplements; functional foods; chromatographic and spectrophotometric methods; natural compounds; polyphenols; antioxidant activity; anti- inflammatory activity; epigenetic effect of food components-mirnas; preclinical studies
Prof. Dr. Simone Carradori
Department of Pharmacy, University “G. d'Annunzio” of Chieti-Pescara, Chieti, Italy
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Interests: medicinal chemistry; innovative (micro)extraction procedures; microwave-assisted extraction; synthetic and natural-derived biologically active molecules; monoamine oxidase inhibitors; carbonic anhydrase inhibitors; anticancer agents; anti-Helicobacter pylori agents; antifungal agents; anti-leishmanial and anti-Malaria compounds
Recently, we accepted an invitation to serve as Guest Editors for this Special Issue, "Discovery of Natural Active Agents against Bacteria, Fungi and Parasites” of the journal Molecules (ISSN 1420-3049 https://www.mdpi.com/journal/molecules). In this regard, we would be pleased if you would agree to contribute an original research paper, a short communication, or a focus review to this issue. Provided below is some information that you may find useful in your consideration of this invitation.
This Special Issue aims to collect and disseminate some of the most significant and recent contributions in the interdisciplinary area of pharmacology, pharmacognosy, and food/medicinal chemistry, with a particular emphasis on the (biotechnological) production, isolation and characterization, biological effects, uses, and analysis of semi-synthetic and natural products. The main applications of these natural active compounds must be strictly focused on microbial (bacterial, fungal and viral) infections, parasite eradication, food contamination and preservation, inhibition of biofilm production and resistance development, herbal formulations, new mechanism of action, structure-activity elucidation, and chemically modified natural compounds with improved biological activity. The biological activity of natural extracts without a proper chemical characteriztion will not be considered.
Prof. Dr. Maria Daglia
Prof. Dr. Simone Carradori
Prof. Dr. Annabella Vitalone
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- antimicrobial agents
- food contamination
- innovative (micro)extraction procedures
- synthetic derivatives inspired by natural scaffolds
- food and food supplements analyses
- pharmaco-toxicological activities
- physiological activities of food and food components
- uses of medicinal plants and fungi
- biofilm and resistance
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Bacterial bioactive inhibit Nitzschia ovalis settlement during early biofilm formation, altering its bacterial community
Authors: Claudia D. Infante1, Francisca Castillo 2 , Gonzalo Icaza 3,4, Francisca Marchant 4, Fernando Silva-Aciares 2,6, Carlos E. Riquelme 2,6
Affiliation: 1. Laboratorio de Biotecnología, Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile
2. Laboratorio de Ecología Microbiana, Centro de Bioinnovación de Antofagasta (CBIA). Facultad de Ciencias del Mar y Recursos Biológicos, Universidad de Antofagasta, Antofagasta, Chile
3. Laboratorio de Complejidad Microbiana y Ecología Funcional. Facultad de Ciencias del Mar y Recursos Biológicos, Universidad de Antofagasta, Antofagasta, Chile
4. Centro de Biotecnología y Bioingeniería, Universidad de Antofagasta, Antofagasta, Chile
5. Departamento de Biotecnología. Universidad de Antofagasta, Antofagasta, Chile
Corresponding Author: Claudia D. Infante; El Llano Subercaseaux 2801, San Miguel, ZIP code: 8910060, Santiago, Chile; [email protected]
Abstract: The symbiotic interaction between marine bacteria and microalgae suggests the existence of a relevant function that controls phytoplanktonic dynamics in the marine environment, which would depend on the bacterial microbiota associated with the microalgae. The marine bacteria Alteromonas sp. Ni1-LEM has inhibitory activity on the adhesion of some diatoms, due to a soluble bioactive compound secreted in the medium. After 48 h of Nitzschia ovalis co-culture with the bacterial compound modified the epiphytic bacterial community, preventing the settlement and formation of primary fouling. A change in the diversity and temporal variability of the microbiota associated with the microalga, was determined by 16S rRNA sequencing targeting the V3–V4 regions using Illumina-MiSeq technology. Bacteroidetes were dominant at the start of culturing, and Proteobacteria increased after 48 h in both fractions (i.e. free-living and adhered bacterial communities). Bacterial abundance and species composition were directly linked to the physiological status of the algae, suggesting distinctive roles during biofilm formation.
Keywords Biofouling, Phytoplankton, Free-living bacteria, Adhered bacteria, Microalga, 16S.