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Molecules, Volume 22, Issue 2

February 2017 - 154 articles

Cover Story: The immense scope for variation in dendritic molecules and their versatile functionalization, with the possibility of multivalent binding, permit the design of highly improved, novel materials. This work shows the advantages of dendronization processes by presenting the synthesis and characterization of different dendronized systems. We were able to achieve final properties with specific potential applications by using different synthetic methodologies for the dendronization process, allowing optimal spatial arrangements of the dendron. View this paper.
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Articles (154)

  • Article
  • Open Access
48 Citations
10,560 Views
12 Pages

Lycium barbarum L. Polysaccharide (LBP) Reduces Glucose Uptake via Down-Regulation of SGLT-1 in Caco2 Cell

  • Huizhen Cai,
  • Xiaohui Yang,
  • Qian Cai,
  • Binbin Ren,
  • Hongyan Qiu and
  • Zhiqing Yao

22 February 2017

Lycium barbarum L. polysaccharide (LBP) is prepared from Lycium barbarum L. (L. barbarum), which is a traditional Chinese medicine. LPB has been shown to have hypoglycemic effects. In order to gain some mechanistic insights on the hypoglycemic effect...

  • Article
  • Open Access
17 Citations
7,790 Views
11 Pages

Synthesis, Characterization and Antibacterial Studies of N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide and Its Neodymium(III) and Thallium(III) Complexes

  • Lawrence Nnamdi Obasi,
  • Uchechukwu Susan Oruma,
  • Ibrahim Abdulrazak Al-Swaidan,
  • Ponnadurai Ramasami,
  • Chigozie Julius Ezeorah and
  • Alfred Ezinna Ochonogor

22 February 2017

N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide (NBTCS) was synthesized by condensation reaction of 4-chlorobenzenesulphonyl chloride and 2-aminobenzothiazole in acetone under reflux. Neodymium(III) and thallium(III) complexes of the ligand were al...

  • Article
  • Open Access
7 Citations
6,675 Views
13 Pages

22 February 2017

A photocatalytic rotating disc reactor (PRD-reactor) with TiO2 nanowire arrays deposited on a thin Ti plate is fabricated and tested for industrial wastewater treatment. Results indicate that the PRD-reactor shows excellent decolorization capability...

  • Article
  • Open Access
25 Citations
7,494 Views
17 Pages

Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma

  • Chaochao Ge,
  • Liping Chang,
  • Ying Zhao,
  • Congcong Chang,
  • Xiaojuan Xu,
  • Haoying He,
  • Yuxia Wang,
  • Fujun Dai,
  • Songqiang Xie and
  • Chaojie Wang

22 February 2017

Two kinds of naphthalimide derivatives were synthesized and evaluated for in vitro their anti-hepatocellular carcinoma properties. Compound 3a with a fused thiazole fragment to naphthalimide skeleton inhibited cell migration of SMMC-7721 and HepG2, a...

  • Article
  • Open Access
23 Citations
7,164 Views
12 Pages

A Study on the Electro-Optical Properties of Thiol-Ene Polymer Dispersed Cholesteric Liquid Crystal (PDChLC) Films

  • Yujian Sun,
  • Yanzi Gao,
  • Le Zhou,
  • Jianhua Huang,
  • Hua Fang,
  • Haipeng Ma,
  • Yi Zhang,
  • Jie Yang,
  • Ping Song and
  • Cuihong Zhang
  • + 4 authors

22 February 2017

In this study, a polymer dispersed cholesteric liquid crystal (PDChLC) film obtained via a one-step fabrication technique based on photopolymerization of a thiol-acrylate reaction system was prepared and characterized for the first time. The effects...

  • Article
  • Open Access
23 Citations
6,756 Views
14 Pages

Immobilization of Lipase from Penicillium sp. Section Gracilenta (CBMAI 1583) on Different Hydrophobic Supports: Modulation of Functional Properties

  • Daniela F. M. Turati,
  • Wilson G. Morais Júnior,
  • César R. F. Terrasan,
  • Sonia Moreno-Perez,
  • Benevides C. Pessela,
  • Gloria Fernandez-Lorente,
  • Jose M. Guisan and
  • Eleonora C. Carmona

22 February 2017

Lipases are promising enzymes that catalyze the hydrolysis of triacylglycerol ester bonds at the oil/water interface. Apart from allowing biocatalyst reuse, immobilization can also affect enzyme structure consequently influencing its activity, select...

  • Article
  • Open Access
28 Citations
8,539 Views
15 Pages

22 February 2017

The use of ketohexose isomerases is a powerful tool in lactose whey processing, but these enzymes can be very sensitive and expensive. Development of immobilized/stabilized biocatalysts could be a further option to improve the process. In this work,...

  • Review
  • Open Access
64 Citations
11,570 Views
23 Pages

Recent Advances and Applications of Molecular Docking to G Protein-Coupled Receptors

  • Damian Bartuzi,
  • Agnieszka A. Kaczor,
  • Katarzyna M. Targowska-Duda and
  • Dariusz Matosiuk

22 February 2017

The growing number of studies on G protein-coupled receptors (GPCRs) family are a source of noticeable improvement in our understanding of the functioning of these proteins. GPCRs are responsible for a vast part of signaling in vertebrates and, as su...

  • Article
  • Open Access
12 Citations
7,695 Views
18 Pages

Diastereoselective Synthesis of Spirocyclopropanes under Mild Conditions via Formal [2 + 1] Cycloadditions Using 2,3-Dioxo-4-benzylidene-pyrrolidines

  • Yi Li,
  • Qing-Zhu Li,
  • Li Huang,
  • Hong Liang,
  • Kai-Chuan Yang,
  • Hai-Jun Leng,
  • Yue Liu,
  • Xu-Dong Shen,
  • Xiao-Jun Gou and
  • Jun-Long Li

22 February 2017

A highly diastereoselective cyclopropanation of cyclic enones with sulfur ylides was developed under catalyst-free conditions, producing multifunctional spirocyclopropanes in generally excellent yields (up to 99% yield and >99:1 d.r.). The asymmet...

  • Article
  • Open Access
8 Citations
7,317 Views
12 Pages

Synthesis of Reusable Silica Nanosphere-Supported Pt(IV) Complex for Formation of Disulfide Bonds in Peptides

  • Xiaonan Hou,
  • Xiaowei Zhao,
  • Yamei Zhang,
  • Aiying Han,
  • Shuying Huo and
  • Shigang Shen

22 February 2017

Some peptide-based drugs, including oxytocin, vasopressin, ziconotide, pramlintide, nesiritide, and octreotide, contain one intramolecular disulfide bond. A novel and reusable monodispersed silica nanosphere-supported Pt(IV) complex (SiO2@TPEA@Pt(IV)...

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Molecules - ISSN 1420-3049