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Molecules, Volume 20, Issue 7

July 2015 - 106 articles

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Articles (106)

  • Article
  • Open Access
78 Citations
8,654 Views
15 Pages

The Antioxidant Activity and Their Major Antioxidant Compounds from Acanthopanax senticosus and A. koreanum

  • Young-Hyun Kim,
  • Myoung Lae Cho,
  • Dan-Bi Kim,
  • Gi-Hae Shin,
  • Jin-Ha Lee,
  • Jong Seok Lee,
  • Sun-Ok Park,
  • Sang-Jong Lee,
  • Hyun Mu Shin and
  • Ok-Hwan Lee

22 July 2015

The antioxidant activity and chlorogenic acid and caffeic acid contents were investigated from different parts of Acanthopanax senticosus and A. koreanum. Antioxidant activity was assessed by various in vitro assays such as DPPH, ABTS, FRAP, reducing...

  • Article
  • Open Access
25 Citations
7,705 Views
17 Pages

Extractions of Oil from Descurainia sophia Seed Using Supercritical CO2, Chemical Compositions by GC-MS and Evaluation of the Anti-Tussive, Expectorant and Anti-Asthmatic Activities

  • Jian-Hong Gong,
  • Yan-Li Zhang,
  • Jin-Li He,
  • Xiao-Ke Zheng,
  • Wei-Sheng Feng,
  • Xiao-Lan Wang,
  • Hai-Xue Kuang,
  • Chun-Ge Li and
  • Yan-Gang Cao

22 July 2015

Descurainia sophia is widely distributed in China and is one of the most troublesome annual weeds. It has diverse medicinal usage. D. sophia has abundant oil, making it an important oil plant in China. The main goal of this study was to obtain the ma...

  • Review
  • Open Access
58 Citations
9,717 Views
11 Pages

Cell-Penetrating Peptides: Possibilities and Challenges for Drug Delivery in Vitro and in Vivo

  • Tore Skotland,
  • Tore Geir Iversen,
  • Maria Lyngaas Torgersen and
  • Kirsten Sandvig

22 July 2015

In this review, we discuss how cell-penetrating peptides (CPPs) might get access to their intracellular targets. We specifically focus on the challenge of deciding whether the positively-charged CPPs are just bound to the negatively-charged cell sur...

  • Article
  • Open Access
24 Citations
5,942 Views
12 Pages

Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans

  • Xin Liu,
  • Junsheng Zhang,
  • Qiao Liu,
  • Guihua Tang,
  • Hongsheng Wang,
  • Chengqi Fan and
  • Sheng Yin

22 July 2015

Four new cembranoids, sarcophelegans A–D (1–4) and six known analogues (5–10) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configurati...

  • Article
  • Open Access
9 Citations
9,869 Views
18 Pages

Iminoiodane- and Brønsted Base-Mediated Cross Dehydrogenative Coupling of Cyclic Ethers with 1,3-Dicarbonyl Compounds

  • Ciputra Tejo,
  • Xiao Rong Sim,
  • Bo Ra Lee,
  • Benjamin James Ayers,
  • Chung-Hang Leung,
  • Dik-Lung Ma and
  • Philip Wai Hong Chan

22 July 2015

A one-pot, two-step approach to prepare 2-tetrahydrofuran and -pyran substituted 1,3-dicarbonyl compounds by PhI=NTs-mediated amination/Brønsted base-catalyzed cross dehydrogenative coupling (CDC) reaction of the cyclic ether and 1,3-dicarbonyl deriv...

  • Article
  • Open Access
23 Citations
6,968 Views
20 Pages

22 July 2015

Endocrine disruptors in water are contaminants of emerging concern due to the potential risks they pose to the environment and to the aquatic ecosystems. In this study, a solar photocatalytic treatment process in a pilot-scale compound parabolic coll...

  • Article
  • Open Access
27 Citations
6,539 Views
10 Pages

In Vivo Antihyperglycemic Activity of a Lanosteryl Triterpene from Protorhus longifolia

  • Rebamang A. Mosa,
  • Nkosinathi D. Cele,
  • Sihle E. Mabhida,
  • Samkelisiwe C. Shabalala,
  • Dambudzo Penduka and
  • Andy R. Opoku

22 July 2015

Control of postprandial hyperglycemia is crucial in the management of diabetes mellitus. Despite the use of the current hypoglycemic drugs, incidence of diabetes and related diseases continue to increase. This study aimed at evaluating the in vivo an...

  • Review
  • Open Access
1,843 Citations
112,155 Views
38 Pages

Molecular Docking and Structure-Based Drug Design Strategies

  • Leonardo G. Ferreira,
  • Ricardo N. Dos Santos,
  • Glaucius Oliva and
  • Adriano D. Andricopulo

22 July 2015

Pharmaceutical research has successfully incorporated a wealth of molecular modeling methods, within a variety of drug discovery programs, to study complex biological and chemical systems. The integration of computational and experimental strategies...

  • Review
  • Open Access
151 Citations
22,499 Views
74 Pages

Secondary Metabolites from Rubiaceae Species

  • Daiane Martins and
  • Cecilia Veronica Nunez

22 July 2015

This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubia...

  • Article
  • Open Access
19 Citations
8,083 Views
15 Pages

The Influence of the Combination of Carboxylate and Phosphinate Pendant Arms in 1,4,7-Triazacyclononane-Based Chelators on Their 68Ga Labelling Properties

  • Gábor Máté,
  • Jakub Šimeček,
  • Miroslav Pniok,
  • István Kertész,
  • Johannes Notni,
  • Hans-Jürgen Wester,
  • László Galuska and
  • Petr Hermann

21 July 2015

In order to compare the coordination properties of 1,4,7-triazacyclononane (tacn) derivatives bearing varying numbers of phosphinic/carboxylic acid pendant groups towards 68Ga, 1,4,7-triazacyclononane-7-acetic-1,4-bis(methylenephosphinic) acid (NOPA)...

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Molecules - ISSN 1420-3049