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19 Results Found

  • Feature Paper
  • Article
  • Open Access
22 Citations
9,151 Views
14 Pages

9 March 2018

Natural hydroxy fatty acids are relevant starting materials for the production of a number of industrial fine chemicals, such as different high-value flavour ingredients. Only a few of the latter hydroxy acid derivatives are available on a large scal...

  • Article
  • Open Access
5 Citations
3,606 Views
23 Pages

25 February 2022

Calcium carbonate has been extensively used as a neutralising agent in acid-forming microbial processes. The effect of increasing calcium carbonate concentrations on Rhizopus delemar has not been previously investigated. In this study, an evaluation...

  • Article
  • Open Access
25 Citations
8,152 Views
16 Pages

Microbial conversion of oleic acid (1) to form value-added industrial products has gained increasing scientific and economic interest. So far, the production of natural lactones with flavor and fragrance properties from fatty acids by non-genetically...

  • Feature Paper
  • Article
  • Open Access
8 Citations
4,462 Views
16 Pages

Recombinant Oleate Hydratase from Lactobacillus rhamnosus ATCC 53103: Enzyme Expression and Design of a Reliable Experimental Procedure for the Stereoselective Hydration of Oleic Acid

  • Antonio Castagna,
  • Davide De Simeis,
  • Erica E. Ferrandi,
  • Stefano Marzorati,
  • Daniela Monti,
  • Stefano Serra and
  • Mattia Valentino

1 October 2020

Different microbial strains are able to transform oleic acid (OA) into 10-hydroxystearic acid (10-HSA) by means of the catalytic activity of the enzymes oleate hydratase (EC 4.2.1.53). Lactobacillus rhamnosus ATCC 53103 performs this biotransformatio...

  • Article
  • Open Access
13 Citations
5,515 Views
13 Pages

22 December 2019

Carbonic anhydrase (CA) is a diffusion-controlled enzyme that rapidly catalyzes carbon dioxide (CO2) hydration. CA has been considered as a powerful and green catalyst for bioinspired CO2 capture and utilization (CCU). For successful industrial appli...

  • Article
  • Open Access
27 Citations
6,606 Views
18 Pages

The Fatty-Acid Hydratase Activity of the Most Common Probiotic Microorganisms

  • Stefano Serra,
  • Davide De Simeis,
  • Antonio Castagna and
  • Mattia Valentino

28 January 2020

In this work, we studied the biotechnological potential of thirteen probiotic microorganisms currently used to improve human health. We discovered that the majority of the investigated bacteria are able to catalyze the hydration reaction of the unsat...

  • Article
  • Open Access
10 Citations
3,296 Views
16 Pages

Phthalides are bioactive compounds that naturally occur in the family Apiaceae. Considering their potentially versatile applications, it is desirable to determine their physical properties, activity and metabolic pathways. This study aimed to examine...

  • Article
  • Open Access
4 Citations
2,586 Views
10 Pages

Natural Compounds Purified from the Leaves of Aristotelia chilensis: Makomakinol, a New Alkaloid and the Effect of Aristoteline and Hobartine on NaV Channels

  • Rebeca Pérez,
  • Claudia Figueredo,
  • Viviana Burgos,
  • Jaime R. Cabrera-Pardo,
  • Bernd Schmidt,
  • Matthias Heydenreich,
  • Andreas Koch,
  • Jennifer R. Deuis,
  • Irina Vetter and
  • Cristian Paz

24 October 2023

Aristotelia chilensis or “maqui” is a tree native to Chile used in the folk medicine of the Mapuche people as an anti-inflammatory agent for the treatment of digestive ailments, fever, and skin lesions. Maqui fruits are black berries whic...

  • Article
  • Open Access
9 Citations
2,425 Views
14 Pages

9 November 2023

This study explores the mechanical properties, as well as the water-reducing and setting delay mechanism, of a novel xylonic acid-based water reducer applied to cementitious materials. Four xylonic acid water reducers were synthesized in this study:...

  • Article
  • Open Access
24 Citations
3,809 Views
12 Pages

Assessing Corneal Endothelial Damage Using Terahertz Time-Domain Spectroscopy and Support Vector Machines

  • Andrew Chen,
  • Zachery B. Harris,
  • Arjun Virk,
  • Azin Abazari,
  • Kulandaiappan Varadaraj,
  • Robert Honkanen and
  • Mohammad Hassan Arbab

23 November 2022

The endothelial layer of the cornea plays a critical role in regulating its hydration by actively controlling fluid intake in the tissue via transporting the excess fluid out to the aqueous humor. A damaged corneal endothelial layer leads to perturba...

  • Article
  • Open Access
4 Citations
3,397 Views
15 Pages

Depletion of Fumarate Hydratase, an Essential TCA Cycle Enzyme, Drives Proliferation in a Two-Step Model

  • Balakrishnan Solaimuthu,
  • Michal Lichtenstein,
  • Arata Hayashi,
  • Anees Khatib,
  • Inbar Plaschkes,
  • Yuval Nevo,
  • Mayur Tanna,
  • Ophry Pines and
  • Yoav D. Shaul

9 November 2022

Fumarate hydratase (FH) is an evolutionary conserved TCA cycle enzyme that reversibly catalyzes the hydration of fumarate to L-malate and has a moonlight function in the DNA damage response (DDR). Interestingly, FH has a contradictory cellular functi...

  • Article
  • Open Access
97 Citations
9,030 Views
14 Pages

Germination and the Early Stages of Seedling Development in Brachypodium distachyon

  • Elzbieta Wolny,
  • Alexander Betekhtin,
  • Magdalena Rojek,
  • Agnieszka Braszewska-Zalewska,
  • Joanna Lusinska and
  • Robert Hasterok

25 September 2018

Successful germination and seedling development are crucial steps in the growth of a new plant. In this study, we investigated the course of the cell cycle during germination in relation to grain hydration in the model grass Brachypodium distachyon (...

  • Article
  • Open Access
5 Citations
2,936 Views
13 Pages

Bioelectrical, Anthropometric, and Hematological Analysis to Assess Body Fluids and Muscle Changes in Elite Cyclists during the Giro d’Italia

  • Álex Cebrián-Ponce,
  • Alfredo Irurtia,
  • Jorge Castizo-Olier,
  • Manuel Vicente Garnacho-Castaño,
  • Javier Espasa-Labrador,
  • Zeasseska Noriega and
  • Marta Carrasco-Marginet

15 March 2023

This study aimed to characterize and monitor the body fluid and muscle changes during the Giro d’Italia in nine elite cyclists via bioelectrical (whole-body and muscle-localized) anthropometric and hematological analysis. There were three checkpoint...

  • Article
  • Open Access
17 Citations
4,458 Views
16 Pages

Nymphoides peltata is widely used pharmacologically in Traditional Chinese Medicine and Ayurvedic medicine as a diuretic, antipyretic, or choleretic and to treat ulcers, snakebites, and edema. Previous studies have shown that phytochemicals from N. p...

  • Article
  • Open Access
15 Citations
5,903 Views
17 Pages

Performance Evaluation and Durability Enhancement of FEP-Based Gas Diffusion Media for PEM Fuel Cells

  • Saverio Latorrata,
  • Paola Gallo Stampino,
  • Cinzia Cristiani and
  • Giovanni Dotelli

5 December 2017

Nowadays, micro-porous layers (MPLs) for polymer electrolyte membrane fuel cells (PEMFCs) are commonly deposited onto gas diffusion layer (GDL) substrates starting from hydrophobic carbon-based dispersions. In this work, different quantities of fluor...

  • Article
  • Open Access
9 Citations
6,806 Views
22 Pages

ApoA-I-Mediated Lipoprotein Remodeling Monitored with a Fluorescent Phospholipid

  • Edward B. Neufeld,
  • Masaki Sato,
  • Scott M. Gordon,
  • Vinay Durbhakula,
  • Nicolas Francone,
  • Angel Aponte,
  • Gizem Yilmaz,
  • Denis Sviridov,
  • Maureen Sampson and
  • Alan T. Remaley
  • + 2 authors

12 July 2019

We describe simple, sensitive and robust methods to monitor lipoprotein remodeling and cholesterol and apolipoprotein exchange, using fluorescent Lissamine Rhodamine B head-group tagged phosphatidylethanolamine (*PE) as a lipoprotein reference marker...

  • Review
  • Open Access
79 Citations
7,165 Views
24 Pages

Desiccation Tolerance as the Basis of Long-Term Seed Viability

  • Galina Smolikova,
  • Tatiana Leonova,
  • Natalia Vashurina,
  • Andrej Frolov and
  • Sergei Medvedev

24 December 2020

Desiccation tolerance appeared as the key adaptation feature of photoautotrophic organisms for survival in terrestrial habitats. During the further evolution, vascular plants developed complex anatomy structures and molecular mechanisms to maintain t...

  • Article
  • Open Access
18 Citations
5,745 Views
20 Pages

Bioactive Poly(lactic acid)–Cocoa Bean Shell Composites for Biomaterial Formulation: Preparation and Preliminary In Vitro Characterization

  • Andres J. Garcia-Brand,
  • Maria A. Morales,
  • Ana Sofia Hozman,
  • Andres C. Ramirez,
  • Luis J. Cruz,
  • Alejandro Maranon,
  • Carolina Muñoz-Camargo,
  • Juan C. Cruz and
  • Alicia Porras

27 October 2021

The unique lignocellulosic and solvent-extractive chemical constituents of most natural fibers are rich in natural polymers and bioactive molecules that can be exploited for biomaterial formulation. However, although natural fibers’ main constituents...

  • Article
  • Open Access
9 Citations
3,423 Views
20 Pages

Production and Characterization of Bacterial Cellulose Separators for Nickel-Zinc Batteries

  • Raymond Leopold Heydorn,
  • Jana Niebusch,
  • David Lammers,
  • Marion Görke,
  • Georg Garnweitner,
  • Katrin Dohnt and
  • Rainer Krull

6 August 2022

The need for energy-storing technologies with lower environmental impact than Li-ion batteries but similar power metrics has revived research in Zn-based battery chemistries. The application of bio-based materials as a replacement for current compone...