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21 Results Found

  • Article
  • Open Access
6 Citations
2,867 Views
11 Pages

10 January 2022

Botulinum neurotoxin type A (BoNT-A) injection and augmentation enterocystoplasty (AE) are alternative and effective management strategies for neurogenic detrusor overactivity (NDO) refractory to pharmacotherapy. A great majority of patients with spi...

(This article belongs to the Special Issue Botulinum Toxins: Old and New Applications in Humans and Animals for the Treatment of Lower Urinary Tract Conditions)
  • Article
  • Open Access
2,290 Views
10 Pages

15 August 2025

Purpose: Detrusor sphincter dyssynergia (DSD), a common lower urinary tract condition in patients with suprasacral spinal cord injury (SCI), can lead to urological complications and reduced quality of life. Urethral sphincter botulinum toxin A (BoNT-...

(This article belongs to the Special Issue Application of Botulinum Neurotoxin in Lower Urinary Tract Dysfunctions: Where Are We Now? II)
  • Article
  • Open Access
2 Citations
1,674 Views
15 Pages

Outcomes of Transobturator Tape Surgery for Stress and Mixed Urinary Incontinence: A 12-Year Retrospective Review

  • Cheng-Feng Lin,
  • Hung-Yi Chen,
  • Chun-Te Wu,
  • Kuan-Lin Liu,
  • Cheng-Chia Lin,
  • Heng-Jung Hsu,
  • Chin-Chan Lee and
  • Chun-Yu Chen

16 October 2025

Background: Stress urinary incontinence (SUI) and mixed urinary incontinence (MUI) are common disorders that impair quality of life. While transobturator tension-free vaginal tape (TVT-O) is established for SUI, outcomes in MUI remain uncertain. Meth...

(This article belongs to the Special Issue Clinical Diagnosis and Management in Urology)
  • Article
  • Open Access
2 Citations
4,194 Views
9 Pages

14 March 2023

Objective: To analyze the role of urodynamic dysfunctions as risk factors for recurrent urinary tract infections (rUTIs) in patients with multiple sclerosis (MS). Material and methods: We conducted a prospective cohort study of 170 patients with MS w...

  • Article
  • Open Access
11 Citations
3,245 Views
13 Pages

Urodynamics Are Essential to Predict the Risk for Upper Urinary Tract Damage after Acute Spinal Cord Injury

  • Veronika Birkhäuser,
  • Collene E. Anderson,
  • Marko Kozomara,
  • Mirjam Bywater,
  • Oliver Gross,
  • Stephan Kiss,
  • Stephanie C. Knüpfer,
  • Miriam Koschorke,
  • Lorenz Leitner and
  • Thomas M. Kessler
  • + 7 authors

We used clinical parameters to develop a prediction model for the occurrence of urodynamic risk factors for upper urinary tract (UUT) damage during the first year after acute spinal cord injury (SCI). A total of 97 patients underwent urodynamic inves...

(This article belongs to the Special Issue Bench to Bedside in Neuro-Urology)
  • Review
  • Open Access
35 Citations
5,603 Views
9 Pages

16 March 2020

Diabetes mellitus (DM) is an independent risk factor for overactive bladder (OAB). The pathophysiology of DM-associated OAB is multifactorial and time-dependent. Diabetic bladder dysfunction is highly associated with diabetic complications, mainly in...

(This article belongs to the Special Issue Botulinum Toxin Treatment for Pain and Inflammation in Functional Urological Disorders)
  • Article
  • Open Access
11 Citations
4,144 Views
11 Pages

2 June 2021

External urethral sphincter (EUS) dysfunction is a common, bothersome female voiding dysfunction. This study aims to analyze the characteristics of different types of female EUS dysfunction, as well as to determine the outcome predictors of sphincter...

(This article belongs to the Special Issue Botulinum Toxins: Old and New Applications in Humans and Animals for the Treatment of Lower Urinary Tract Conditions)
  • Article
  • Open Access
5 Citations
2,695 Views
9 Pages

15 December 2022

Voiding dysfunction is a common but bothersome problem in both men and women. Urethral sphincter botulinum toxin A (BoNT-A) injections could serve as an option in refractory cases. This study analyzed the efficacy and outcome predictors of the inject...

(This article belongs to the Special Issue Application of Botulinum Neurotoxin in Lower Urinary Tract Dysfunctions: Where Are We Now?)
  • Article
  • Open Access
13 Citations
3,909 Views
9 Pages

19 November 2019

A botulinum toxin A (BoNT-A) intravesical injection can improve the symptoms of interstitial cystitis/bladder pain syndrome (IC/BPS). Patients with IC/BPS have different clinical characteristics, urodynamic features, and cystoscopic findings. This st...

(This article belongs to the Special Issue Botulinum Toxin Treatment for Pain and Inflammation in Functional Urological Disorders)
  • Systematic Review
  • Open Access
12 Citations
3,750 Views
12 Pages

Response to Treatment with Botulinum Neurotoxin A (BoNT-A) in Children and Adolescents with Neurogenic Lower Urinary Tract Dysfunction and Idiopathic Overactive Bladder: A Systematic Review and Meta-Analysis

  • Andrea Panunzio,
  • Rossella Orlando,
  • Giovanni Mazzucato,
  • Sonia Costantino,
  • Giulia Marafioti Patuzzo,
  • Clara Cerrato,
  • Rita De Mitri,
  • Vincenzo Pagliarulo,
  • Alessandro Tafuri and
  • Maria Angela Cerruto
  • + 4 authors

15 October 2024

Introduction: Botulinum neurotoxin A (BoNT-A) is a treatment option for neurogenic lower urinary tract dysfunctions (NLUTD) and idiopathic overactive bladder (OAB) in adults. Recently, its use has gained popularity in paediatric urology. Transitional...

(This article belongs to the Section Bacterial Toxins)
  • Article
  • Open Access
10,117 Views
9 Pages

Comparative Effectiveness and Safety of Finasteride and Dutasteride in the Treatment of Benign Prostatic Hyperplasia: A Real-World Retrospective Study

  • Jarosław Ratajski,
  • Kamil Ciechan,
  • Paweł Jędrzejczyk,
  • Tomasz W. Kaminski,
  • Patryk Uciechowski and
  • Tomasz Ząbkowski

30 October 2025

Background and Objectives: Benign prostatic hyperplasia (BPH) is one of the most common chronic conditions in older men, significantly impairing quality of life (QoL) by causing lower urinary tract symptoms (LUTSs). 5-alpha-reductase inhibitors (5-AR...

(This article belongs to the Section Urology & Nephrology)
  • Article
  • Open Access
16 Citations
7,767 Views
12 Pages

30 July 2015

Although intravesical injection of onabotulinumtoxinA (BoNT-A) has been proved promising in treating patients with interstitial cystitis/bladder pain syndrome (IC/BPS), what kind of patients that may benefit from this treatment remains unclear. This...

(This article belongs to the Collection Botulinum Toxins on Human Pain)
  • Article
  • Open Access
2,031 Views
10 Pages

Are Urethral Pressure Profile Measurements Effective in Diagnosing Urodynamic Stress Incontinence in Women Presenting with Stress or Mixed Urinary Incontinence? Results from a Cross-Sectional Study

  • Konstantinos Pantazis,
  • Themistoklis Mikos,
  • Sofia Tsiapakidou,
  • Iakovos Theodoulidis,
  • Stamatios Petousis,
  • Konstantinos Dinas,
  • Antonio Schiattarella,
  • Antonio Simone Laganà and
  • Apostolos P. Athanasiadis

1 July 2025

Background and Objectives: This study aims to evaluate the relevance of urethral pressure profile (UPP) measurements in the diagnosis of urodynamic stress incontinence (USI) in women with stress and mixed urinary incontinence (SUI and MUI). Materials...

(This article belongs to the Special Issue New Insights into Gynecological Disease)
  • Article
  • Open Access
2 Citations
1,730 Views
9 Pages

10 September 2024

Background: The Minimally Invasive Prolapse System (MIPS) device, a novel single-incision transvaginal mesh, represents recent advancements in mesh technology, providing lightweight, biocompatible support for pelvic organ prolapse while reducing eros...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
1 Citations
3,124 Views
12 Pages

17 April 2025

Neurogenic detrusor overactivity (NDO) is a complex condition associated with detrusor overactivity, reduced bladder compliance, and high intravesical pressures, potentially leading to urinary tract infections (UTIs) and renal impairment. This retros...

(This article belongs to the Special Issue Application of Botulinum Neurotoxin in Lower Urinary Tract Dysfunctions: Where Are We Now? II)
  • Review
  • Open Access
19 Citations
8,956 Views
12 Pages

Detrusor Underactivity in Men with Bladder Outlet Obstruction

  • Hsiang-Ying Lee,
  • Chien-Sheng Wang and
  • Yung-Shun Juan

17 November 2022

Detrusor underactivity (DU) and bladder outlet obstruction (BOO) are both common troublesome causes of lower urinary tract symptoms (LUTS) and often impact on quality of life simultaneously in men. This article aims to focus on DU with BOO in male pa...

(This article belongs to the Special Issue Bladder Dysfunction: From Molecular Pathology to Therapeutic Approaches)
  • Article
  • Open Access
1,519 Views
9 Pages

Background/Objectives: De novo stress urinary incontinence (SUI) can develop postoperatively in patients without prior symptoms, and can persist beyond 6 months, posing clinical challenges. This study aimed to identify predictors of persistent de nov...

(This article belongs to the Section Molecular and Translational Medicine)
  • Review
  • Open Access
17 Citations
7,726 Views
10 Pages

Pelvic Organ Prolapse Syndrome and Lower Urinary Tract Symptom Update: What’s New?

  • Gaetano Maria Munno,
  • Marco La Verde,
  • Davide Lettieri,
  • Roberta Nicoletti,
  • Maria Nunziata,
  • Diego Domenico Fasulo,
  • Maria Giovanna Vastarella,
  • Marika Pennacchio,
  • Gaetano Scalzone and
  • Marco Torella
  • + 4 authors

(1) Background: This narrative review aimed to analyze the epidemiological, clinical, surgical, prognostic, and instrumental aspects of the link between pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTS), collecting the most recent e...

(This article belongs to the Special Issue Urinary Tract Health and Care)
  • Article
  • Open Access
1 Citations
2,057 Views
12 Pages

Cracking the LUTS Code: A Pre-Urodynamic Tool for DU vs. BOO Diagnosis in Female Patients with Non-Neurogenic LUTS

  • Karolina Garbas,
  • Łukasz Zapała,
  • Aleksander Ślusarczyk,
  • Tomasz Piecha and
  • Piotr Radziszewski

23 May 2025

Background: Detrusor underactivity (DU) and bladder outlet obstruction (BOO) are common causes of voiding dysfunction in women with lower urinary tract symptoms (LUTS). However, differentiating between them remains challenging due to overlapping clin...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
2 Citations
1,285 Views
17 Pages

27 November 2025

Objective: The current study aimed to develop predictive models based on noninvasive clinical parameters to facilitate the early identification and stratification of patients with suspected bladder outlet dysfunction (BOD), thereby reducing the need...

(This article belongs to the Topic Clinical, Translational, and Basic Research and Novel Therapy on Functional Bladder Diseases and Lower Urinary Tract Dysfunctions)
  • Article
  • Open Access
697 Views
11 Pages

How to Minimize Hyper-Continence After Intracorporeal Robotic Neobladder Configuration in Women? The Three-Layer Posterior Reconstruction During Florence Robotic IntraCorporeal Neobladder (FloRIN)

  • Fabrizio Di Maida,
  • Luca Lambertini,
  • Antonio Andrea Grosso,
  • Vincenzo Salamone,
  • Daniele Paganelli,
  • Laura Di Stefano,
  • Francesca Conte,
  • Filippo Lipparini,
  • Matteo Salvi and
  • Andrea Minervini
  • + 2 authors

26 November 2025

Background: Orthotopic neobladder in women presents functional challenges, notably hyper-continence requiring intermittent self-catheterization. Here, we describe a three-layer urethro-ileal anastomosis incorporating a peritoneal flap and evaluate it...

(This article belongs to the Section General Surgery)