Importance of Urodynamic Dysfunctions as Risk Factors for Recurrent Urinary Tract Infections in Patients with Multiple Sclerosis
Abstract
:1. Introduction
- (a)
- Detrusor overactivity without obstruction
- (b)
- Detrusor overactivity with outlet obstruction (detrusor external sphincter dyssynergia—DSD)
- (c)
- Detrusor overactivity with impaired contractility
- (d)
- Detrusor areflexia
- (e)
- Normal function.
2. Materials and Methods
3. Results
3.1. Descriptive Statistics
3.2. Inferential Statistics
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | Patients with rUTIs | Patients without rUTIs | Significance Level |
---|---|---|---|
Women/men * | 31 (84%)/7 (16%) | 47 (61%)/30 (39%) | 0.068 |
Age (years) † | 51 ± 10.8 | 49 ± 9.5 | 0.091 |
Storage LUTS * | 23 (62%) | 43 (56%) | 0.339 |
Voiding LUTS * | 10 (27%) | 19 (25%) | 0.494 |
Mixed LUTS * | 5 (15%) | 12 (16%) | 0.483 |
Symptom progression time (months) † | 9 ± 6.5 | 6 ± 5.4 | 0.016 ‡ |
Performing CIC * | 3 (8%) | 2 (3%) | 0.197 |
MS duration (months) † | 20 ± 9.2 | 16 ± 7.6 | 0.010 ‡ |
EDSS score † | 5.3 ± 2.11 | 4.4 ± 2.08 | 0.015 ‡ |
PPMS or SPMS MS type * | 19 (51%) | 25 (32%) | 0.042 ‡ |
MS treatment * | None: 12 (32%) First line: 13 (36%) Second line 12 (32%) | None: 21 (27%) First line: 31 (41%) Second line:25 (32%) | 0.819 |
Variable | Patients with rUTIs | Patients without rUTIs | Significance Level |
---|---|---|---|
Voided volume (mL) † | 103 ± 135.3 | 216 ± 195.5 | 0.000 ‡ |
Maximum flow rate (mL/s) † | 9 ± 7.8 | 15 ± 8.6 | 0.002 ‡ |
Post-void residual volume (mL) † | 73 ± 84.7 | 80 ± 137.5 | 0.416 |
Bladder voiding efficiency (%) † | 35 ± 37.0 | 21 ± 26.2 | 0.026 ‡ |
Cystometric capacity (mL) † | 208 ± 124.8 | 235 ± 125.8 | 0.145 |
Bladder compliance (mL/cm H2O) † | 62 ± 64.9 | 58 ± 51.8 | 0.362 |
Detrusor overactivity * | 12 (26%) | 25 (38%) | 0.135 |
Maximum detrusor pressure during involuntary contraction (cm H2O) † | 44 ± 22.9 | 36 ± 29.2 | 0.339 |
Stress urinary incontinence * | 12 (52%) | 25 (28%) | 0.030 ‡ |
Maximum detrusor voiding pressure (cm H2O) † | 36 ± 27.1 | 44 ± 30.9 | 0.093 |
Detrusor pressure at maximum flow (cm H2O) † | 22 ± 19.8 | 29 ± 20.3 | 0.046 ‡ |
BCI † | 72 ± 45.3 | 88 ± 44.6 | 0.045 ‡ |
BOOI † | 3 ± 27.1 | 6 ± 23.5 | 0.278 |
Detrusor-sphincter dyssynergia * | 14 (32%) | 20 (29%) | 0.222 |
Variables | ß | p | R2 |
---|---|---|---|
MS type | 0.595 | 0.430 | 0.357 |
Maximum Flow rate | −0.110 | 0.081 | |
Sex | −1.224 | 0.267 | |
MS duration | 0.053 | 0.427 | |
Symptoms progression time | 0.041 | 0.631 | |
EDSS score | −0.139 | 0.405 | |
Bladder voiding efficiency | 0.003 | 0.405 | |
Stress urinary incontinence | 1.495 | 0.037 | |
Maximum detrusor voiding pressure | 0.016 | 0.454 | |
Detrusor pressure at maximum flow | |||
BCI | −0.003 | 0.785 | |
Constant | −0.849 | 0.564 |
Variables | ß | p | R2 |
---|---|---|---|
Maximum Flow rate | −0.110 | 0.081 | 0.407 |
Stress urinary incontinence | 1.495 | 0.037 |
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Vírseda-Chamorro, M.; Salinas-Casado, J.; Matias-Guiu, J. Importance of Urodynamic Dysfunctions as Risk Factors for Recurrent Urinary Tract Infections in Patients with Multiple Sclerosis. Uro 2023, 3, 82-90. https://doi.org/10.3390/uro3010011
Vírseda-Chamorro M, Salinas-Casado J, Matias-Guiu J. Importance of Urodynamic Dysfunctions as Risk Factors for Recurrent Urinary Tract Infections in Patients with Multiple Sclerosis. Uro. 2023; 3(1):82-90. https://doi.org/10.3390/uro3010011
Chicago/Turabian StyleVírseda-Chamorro, Miguel, Jesús Salinas-Casado, and Jorge Matias-Guiu. 2023. "Importance of Urodynamic Dysfunctions as Risk Factors for Recurrent Urinary Tract Infections in Patients with Multiple Sclerosis" Uro 3, no. 1: 82-90. https://doi.org/10.3390/uro3010011