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17 Results Found

  • Article
  • Open Access
3 Citations
3,736 Views
12 Pages

Quality Control of Microscopic Diagnosis of Malaria in Healthcare Facilities and Submicroscopic Infections in Mossendjo, the Department of Niari, the Republic of the Congo

  • Grâce Petula Urielle Fila-Fila,
  • Felix Koukouikila-Koussounda,
  • Fabien Roch Niama,
  • Lauriate Prudencie Bissombolo Madingou and ,
  • Jordy Exaucé Demboux,
  • Aldi Fred Mandiangou,
  • Stéphane Vembe Mahounga,
  • Ahmed Jordy Doniama,
  • Louis Régis Dossou-Yovo and
  • Pembe Issamou Mayengue
  • + 6 authors+ 1 author

21 August 2024

The control and management of malaria are linked to the quality of diagnosis. We sought to estimate the performance of routine microscopy for malaria diagnosis and assess the prevalence of submicroscopic Plasmodium (P.) falciparum infection among feb...

(This article belongs to the Special Issue Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections)
  • Article
  • Open Access
6 Citations
4,277 Views
12 Pages

The Impact of Submicroscopic Parasitemia on Malaria Rapid Diagnosis in Northeastern Tanzania, an Area with Diverse Transmission Patterns

  • Robert Diotrephes Kaaya,
  • Johnson Matowo,
  • Debora Kajeguka,
  • Filemoni Tenu and ,
  • Boniface Shirima,
  • Franklin Mosha and
  • Reginald Kavishe
  • + 2 authors+ 0 author

25 October 2022

Global malaria epidemiology has changed in the last decade with a substantial increase in cases and deaths being recorded. Tanzania accounts for about 4% of all cases and deaths reported in recent years. Several factors contribute to the resurgence o...

  • Article
  • Open Access
939 Views
14 Pages

Submicroscopic Plasmodium falciparum Carriage and Molecular Markers of Antimalarial Drug Resistance Among Outpatients Attending Korle Bu Teaching Hospital, Ghana

  • Benjamin Tetteh Mensah,
  • Hannah Otu,
  • Dorinda Naa Okailey Armah,
  • Comfort Teiko Abuanor and ,
  • Lucas Amenga-Etego and
  • Samuel Antwi-Baffour
  • + 1 author+ 0 author

Background: Malaria remains a major public health challenge in sub-Saharan Africa, where asymptomatic infections continue to hinder elimination efforts. Although the clinical and epidemiological consequences of microscopic infections are well documen...

(This article belongs to the Special Issue Advances in Tools for Battling Malaria)
  • Brief Report
  • Open Access
1 Citations
897 Views
9 Pages

Post-Deployment Screening of Thailand Military Units Deployed to South Sudan from 2023 to 2025 Reveals High Rates of Sub-Microscopic P. falciparum Malaria

  • Min Kramyoo,
  • Sidhartha Chaudhury,
  • Watcharee Yokanit,
  • Kamonwan Siriwattanakul and ,
  • Porruthai Kittikanara,
  • Brian A. Vesely,
  • Darunee Utennam,
  • Nakarin Sansanayudh and
  • Sutchana Tabprasit
  • + 4 authors+ 0 author

Peacekeeping operations in sub-Saharan Africa continue to be impacted by malaria both in-country and among returning service members. The Royal Thai Army (RTA) deploys an engineering company to Juba and Rumbek, South Sudan to conduct peacekeeping ope...

(This article belongs to the Special Issue Military Medicine: An Everlasting War against Tropical and Infectious Diseases)
  • Article
  • Open Access
4 Citations
2,899 Views
9 Pages

An Ultra-Sensitive Technique: Using Pv-mtCOX1 qPCR to Detect Early Recurrences of Plasmodium vivax in Patients in the Brazilian Amazon

  • Laila R. A. Barbosa,
  • Emanuelle L. da Silva,
  • Anne C. G. de Almeida,
  • Yanka E. A. R. Salazar and ,
  • André M. Siqueira,
  • Maria das Graças Costa Alecrim,
  • José Luiz Fernandes Vieira,
  • Quique Bassat,
  • Marcus V. G. de Lacerda and
  • Gisely C. Melo
  • + 6 authors+ 1 author

30 December 2020

Background: Early recurrence of Plasmodium vivax is a challenge for malaria control in the field, particularly because this species is associated with lower parasitemia, which hinders diagnosis and monitoring through blood smear testing. Early recurr...

(This article belongs to the Special Issue Addressing Plasmodium vivax: From Control to Elimination)
  • Article
  • Open Access
5 Citations
1,772 Views
14 Pages

Molecular Profiles of Antimalarial Drug Resistance in Plasmodium Species from Asymptomatic Malaria Carriers in Gia Lai Province, Vietnam

  • Hương Giang Lê,
  • Tuấn Cường Võ,
  • Jung-Mi Kang,
  • Chau Van Khanh and ,
  • Nguyen Thi Minh Trinh,
  • Nguyen Thi Lien Hanh,
  • Minkyoung Cho,
  • Huynh Hong Quang and
  • Byoung-Kuk Na
  • + 4 authors+ 0 author

Asymptomatic malaria infection is a major concern in the fight against malaria, as it can act as a significant reservoir for its silent spread or transmission. Therefore, surveillance to detect asymptomatic subjects, particularly in regions with high...

(This article belongs to the Special Issue Research on Mosquito-Borne Pathogens)
  • Article
  • Open Access
14 Citations
5,041 Views
16 Pages

Dry Post Wintertime Mass Surveillance Unearths a Huge Burden of P. vivax, and Mixed Infection with P. vivax P. falciparum, a Threat to Malaria Elimination, in Dhalai, Tripura, India

  • Ipsita Pal Bhowmick,
  • Tulika Nirmolia,
  • Apoorva Pandey,
  • Sarala K. Subbarao and ,
  • Aatreyee Nath,
  • Susmita Senapati,
  • Debabrata Tripathy,
  • Rocky Pebam,
  • Suman Nag and
  • Kanwar Narain
  • + 21 authors+ 16 authors

29 September 2021

With India aiming to achieve malaria elimination by 2030, several strategies have been put in place. With that aim, mass surveillance is now being conducted in some malaria-endemic pockets. As dry season mass surveillance has been shown to have its i...

(This article belongs to the Special Issue Addressing Plasmodium vivax: From Control to Elimination)
  • Article
  • Open Access
8 Citations
3,263 Views
11 Pages

Clinical and Parasitological Profiles of Gestational, Placental and Congenital Malaria in Northwestern Colombia

  • Jaiberth Antonio Cardona-Arias,
  • Luis Felipe Higuita-Gutiérrez and
  • Jaime Carmona-Fonseca

This study compared the clinical–parasitological profiles of gestational (GM), placental (PM), and congenital (CM) malaria in northwestern Colombia. A cross-sectional study with 829 pregnant women, 549 placentas, and 547 newborns was conducted....

(This article belongs to the Special Issue Malaria Elimination: Current Insights and Challenges)
  • Communication
  • Open Access
3,049 Views
9 Pages

Highly Sensitive and Rapid Quantitative Detection of Plasmodium falciparum Using an Image Cytometer

  • Muneaki Hashimoto,
  • Kazumichi Yokota,
  • Kazuaki Kajimoto,
  • Musashi Matsumoto and ,
  • Atsuro Tatsumi,
  • Yoshihiro Nakajima,
  • Toshihiro Mita,
  • Noboru Minakawa,
  • Hiroaki Oka and
  • Masatoshi Kataoka
  • + 5 authors+ 0 author

The gold standard for malaria diagnosis is microscopic examination of blood films by expert microscopists. It is important to detect submicroscopic and asymptomatic Plasmodium infections in people, therefore the development of highly sensitive device...

(This article belongs to the Special Issue Rapid Diagnosis of Microbial Pathogens)
  • Brief Report
  • Open Access
2 Citations
1,647 Views
9 Pages

Ex Vivo Drug Susceptibility of Plasmodium malariae Isolates to Antimalarial Drugs in Gabon

  • Yudi T. Pinilla,
  • Anton Hoffmann,
  • Maxim Viehweg,
  • Nathanaël Saison and ,
  • Stravensky Terence Boussougou Sambe,
  • Ange Gatien Doumba Ndalembouly,
  • Barclaye Ngossanga,
  • Florence Awamu,
  • Ayola Akim Adegnika and
  • Steffen Borrmann
  • + 5 authors+ 0 author

Plasmodium malariae is a neglected human malaria parasite despite its global distribution and propensity for persistent, sub-microscopic infections, which are associated with a mild but significant disease burden. Artemisinin-based therapies appear t...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
386 Views
14 Pages

Implementation of a Composite Reference Standard Methodology in the Greek National Malaria Reference Center, Insights from a Seven-Year Experience

  • Nikolaos Tegos,
  • Leonidas Georgalis,
  • Anastasia Bimpa,
  • Anastasia Panagopoulou and ,
  • Stavroula Beleri,
  • Vasilios Papavasilopoulos,
  • Annita Vakali,
  • Chrisovaladou Kefaloudi,
  • Danai Pervanidou and
  • Eleni Patsoula
  • + 6 authors+ 1 author

Background: Malaria is currently ranked as an important public health issue in Greece despite its initial eradication back in 1974. Given that the clinical picture is often nonspecific, the need for the implementation of targeted laboratory methodolo...

  • Article
  • Open Access
4 Citations
2,151 Views
15 Pages

Changes in Lipid Profile Secondary to Asymptomatic Malaria in Migrants from Sub-Saharan Africa: A Retrospective Analysis of a 2010–2022 Cohort

  • Diego Gayoso-Cantero,
  • María Dolores Corbacho-Loarte,
  • Clara Crespillo-Andújar,
  • Sandra Chamorro-Tojeiro and ,
  • Francesca Norman,
  • Jose A. Perez-Molina,
  • Marta González-Sanz,
  • Oihane Martín,
  • José Miguel Rubio and
  • Begoña Monge-Maillo
  • + 8 authors+ 3 authors

Altered lipid profiles have been observed in acute malaria, though mechanisms remain unclear. The impact of asymptomatic submicroscopic malaria infection (AMI) on lipids is unexploredAn observational, comparative, retrospective study was conducted of...

(This article belongs to the Section Vector-Borne Diseases)
  • Article
  • Open Access
653 Views
26 Pages

The Persistence of High Maternal Anaemia and Low Birthweight Despite Declining Malaria Transmission and Prevalence in Ghana

  • Harry Tagbor,
  • Joseph Osarfo,
  • Doris Okyere,
  • Ekoue Kouevidjin and ,
  • Matilda Aberese-Ako and
  • Gifty Dufie Ampofo
  • + 1 author+ 0 author

Despite declining malaria transmission, maternal anaemia and low birthweight (LBW) remain high in Ghana, suggesting that non-malarial determinants now dominate these outcomes. A cohort of 5197 pregnant women was enrolled at eight health facilities ac...

(This article belongs to the Special Issue Malaria in a Changing World)
  • Article
  • Open Access
18 Citations
5,934 Views
13 Pages

Contrasting Asymptomatic and Drug Resistance Gene Prevalence of Plasmodium falciparum in Ghana: Implications on Seasonal Malaria Chemoprevention

  • Cheikh Cambel Dieng,
  • Lauren Gonzalez,
  • Kareen Pestana,
  • Shittu B. Dhikrullahi and ,
  • Linda E. Amoah,
  • Yaw A. Afrane and
  • Eugenia Lo
  • + 2 authors+ 0 author

16 July 2019

Malaria is a significant public health problem in Ghana. Seasonal Malaria Chemoprevention (SMC) using a combination of sulfadoxine-pyrimethamine and amodiaquine has been implemented since 2015 in northern Ghana where malaria transmission is intense a...

(This article belongs to the Section Microbial Genetics and Genomics)
  • Review
  • Open Access
524 Views
18 Pages

Malaria diagnosis remains challenging in low-density, asymptomatic, mixed-species, and non-falciparum infections. This scoping review mapped the diagnostic and operational evidence for high-resolution melting (HRM) analysis in malaria. Following PRIS...

(This article belongs to the Special Issue Malaria: Updates on Prevention, Diagnosis, and Treatment)
  • Article
  • Open Access
12 Citations
4,200 Views
20 Pages

Effectiveness of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine in Pregnancy: Low Coverage and High Prevalence of Plasmodium falciparum dhfr-dhps Quintuple Mutants as Major Challenges in Douala, an Urban Setting in Cameroon

  • Carole Else Eboumbou Moukoko,
  • Loick Pradel Kojom Foko,
  • Angèle Ayina,
  • Bernard Tornyigah and ,
  • Annie Rachel Epote,
  • Ida Calixte Penda,
  • Patricia Epee Eboumbou,
  • Serge Bruno Ebong,
  • Gaetan Texier and
  • Albert Same Ekobo
  • + 8 authors+ 3 authors

Intermittent preventive treatment in pregnancy with sulfadoxine and pyrimethamine (IPTp-SP) is a key component in the malaria control strategy implemented in Africa. The aim of this study was to determine IPTp-SP adherence and coverage, and the impac...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
1 Citations
1,698 Views
26 Pages

Background: Malaria remains a major public health concern in Africa, due to the persistence of Plasmodium falciparum gametocytes that sustain transmission post treatment. This study evaluated the effects of artemether–lumefantrine (AL) alone co...

(This article belongs to the Section Infectious Diseases)