Advances in Tools for Battling Malaria

Dear Colleagues,

Malaria is an infection that has haunted mankind for centuries. Despite decades of efforts to eradicate this parasitic disease, malaria still exerts a significant healthcare burden, costing lives and compromising the quality of life of the nearly half of the world’s population that live in malaria risk areas. The vulnerability of frameworks installed to control and eliminate malaria was clearly demonstrated during the COVID-19 pandemic, which resulted in a resurgence in the global malaria burden. In addition, efforts to eliminate the disease have been challenged by the fast development of resistance to artemisinin and its derivatives (ARTs), as well as the resistance of Plasmodium falciparum (the most fatal human malaria parasite) to partner drugs used in artemisinin-based combination therapy (ACT), the persistence of vivax malaria in communities, and the emergence of zoonotic malaria caused by several simian malaria parasites, particularly P. knowlesi, which complicates the diagnosis, management, transmission modelling, and control of malaria in affected areas. Clearly, many knowledge gaps remain to be filled before we can put together an optimal strategy to curb the transmission of this parasitic disease. This Special Issue aims to assemble the latest progress in malaria research, with the intention of creating a platform of consolidated information about the disease that may inspire the development of novel strategies to mitigate infections. We welcome contributions that cover, but are not restricted to, the following aspects of malaria:

• Disease pathobiology;
• Parasite–host interaction biology;
• Genomics, transcriptomics, and metabolomics of parasites or hosts pertaining to malaria transmission;
• Transmission modelling and prediction;
• Diagnosis;
• Vector biology and control;
• Disease epidemiology and surveillance;
• Public health, health economics, and policies;
• Drug discoveries;
• Monitoring of treatment efficacy;
• Disease control and prevention.

Contributions may be in one of the following formats:

• Original article;
• Review;
• Case report;
• Methodology/protocol;
• Clinical trial.

We look forward to receiving your contribution. Thank you for your consideration.

Dr. Wenn-Chyau Lee
Dr. Meng Yee Lai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• plasmodium
• control and prevention
• transmission modelling
• diagnosis
• treatment and management