Skip to Content
You are currently on the new version of our website. Access the old version .

10 Results Found

  • Article
  • Open Access
14 Citations
7,108 Views
11 Pages

Synthesis and Anticancer Activities of Novel Guanylhydrazone and Aminoguanidine Tetrahydropyran Derivatives

  • Fábio Pedrosa Lins Silva,
  • Bruna Braga Dantas,
  • Gláucia Veríssimo Faheina Martins,
  • Demétrius Antônio Machado De Araújo and
  • Mário Luiz Araújo de Almeida Vasconcellos

In this paper we present the convenient syntheses of six new guanylhydrazone and aminoguanidine tetrahydropyran derivatives 2–7. The guanylhydrazone 2, 3 and 4 were prepared in 100% yield, starting from corresponding aromatic ketones 8a–c and aminogu...

(This article belongs to the Section Bioorganic Chemistry)
  • Article
  • Open Access
4 Citations
2,999 Views
10 Pages

Effect of an Eco-Friendly Cuminaldehyde Guanylhydrazone Disinfectant on Shiga Toxin Production and Global Transcription of Escherichia coli

  • Yan Wang,
  • William M. Hart-Cooper,
  • Reuven Rasooly,
  • Michelle Qiu Carter and ,
  • William J. Orts,
  • Yongqiang Gu and
  • Xiaohua He
  • + 2 authors+ 0 author

2 November 2022

Antimicrobials have been important medicines used to treat various infections. However, some antibiotics increase the expression of Shiga toxin (Stx). Also, the pervasive use of persistent antibiotics has led to ecotoxicity and antibiotic resistance....

(This article belongs to the Section Bacterial Toxins)
  • Article
  • Open Access
13 Citations
7,019 Views
15 Pages

Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design

  • Wanessa Azevedo de Brito,
  • Monique Gomes Dantas,
  • Fernando Henrique Andrade Nogueira,
  • Edeildo Ferreira da Silva-Júnior and ,
  • João Xavier de Araújo-Júnior,
  • Thiago Mendonça de Aquino,
  • Êurica Adélia Nogueira Ribeiro,
  • Lilian Grace Da Silva Solon,
  • Cícero Flávio Soares Aragão and
  • Ana Paula Barreto Gomes
  • + 5 authors+ 0 author

30 August 2017

Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly ch...

  • Communication
  • Open Access
1 Citations
1,006 Views
5 Pages

Synthesis and Characterization of Novel Pyridinium Salts of (E)-2-(Pyridin-4-ylmethylene)hydrazine-1-carboximidamide

  • Fatemeh Ataie Alani,
  • Fatemeh Ahmadian,
  • Alireza Houshdar Tehrani and
  • Salimeh Amidi

1 October 2025

We report the synthesis and characterization of the novel pyridinium salts from (E)-2-(pyridin-4-ylmethylene)hydrazine-1-carboximidamide. The pyridinium salts were obtained via the reaction of guanylhydrazone derived from pyridine-4-carbaldehyde with...

(This article belongs to the Section Organic Synthesis and Biosynthesis)
  • Article
  • Open Access
2,128 Views
17 Pages

Unexpected Products of Salicylidene-Aminoguanidine Reactions with Metal Ions—Synthesis and Structural Aspects

  • Mirjana M. Radanović,
  • Ljiljana S. Vojinović-Ješić,
  • Niko S. Radulović,
  • Vidak N. Raičević and ,
  • Vukadin M. Leovac and
  • Marko V. Rodić
  • + 1 author+ 0 author

11 December 2024

Due to the promising characteristics of aminoguanidine Schiff bases, ongoing research focuses on synthesizing and characterizing different compounds of this class to establish structure–property relationships. However, the pronounced alkalinity...

  • Article
  • Open Access
602 Views
17 Pages

Two New Zinc(II) Complexes with Symmetric and Asymmetric 2,6-Diacetylpyridine–Aminoguanidine Schiff Bases: Synthesis, Crystal Structures, and Comparative Study

  • Marijana S. Regojević,
  • Valentina M. Vukobrat,
  • Milica G. Bogdanović,
  • Marko V. Rodić and ,
  • Ivana Đ. Borišev,
  • Berta Barta Holló and
  • Mirjana M. Radanović
  • + 2 authors+ 0 author

2 September 2026

Novel compounds based on symmetric and asymmetric 2,6-diacetylpyridine (DAP) Schiff bases were synthesized. A new salt of the symmetric Schiff base 2,6-diacetylpyridine-bis(aminoguanidine), L1∙3HCl∙2H2O, and its zinc(II) complex, [Zn(L1)(...

(This article belongs to the Special Issue Metal-Based Compounds: Relevance for the Biomedical Field, 3rd Edition)
  • Article
  • Open Access
4 Citations
2,987 Views
12 Pages

Effects of Medium Supplements on Somatic Embryo Maturation and DNA Methylation in Pseudotsuga gaussenii Flous, a Species under Protection

  • Ying Gao,
  • Xiaoyi Chen,
  • Ying Cui,
  • Huanhuan Zhao and ,
  • Ruirui Zhao,
  • Chengbi Liu,
  • Jian Zhao,
  • Jinfeng Zhang and
  • Lisheng Kong
  • + 4 authors+ 0 author

11 February 2022

Pseudotsuga gaussenii is a forest species under protection in China. Propagation via somatic embryogenesis is efficient and needed for recovering this species. In this research, effects of medium supplements, i.e., methylglyoxal-bis (guanylhydrazone)...

(This article belongs to the Section Genetics and Molecular Biology)
  • Article
  • Open Access
1 Citations
443 Views
18 Pages

18 August 2026

Exogenous melatonin can alleviate cold injury in post-harvested fruit during fruit refrigeration. The mechanism of melatonin-mediated cold tolerance is increasingly being focused on in studies. However, in cold + melatonin-treated fruit, the changes...

(This article belongs to the Section Horticultural Science and Ornamental Plants)
  • Article
  • Open Access
260 Views
16 Pages

12 October 2026

Exogenous melatonin can elevate the tolerance of plants to drought stress. The mechanism of melatonin-mediated tolerance has been extensively studied. Numerous studies have shown that melatonin treatment can increase contents of osmotic adjustment su...

(This article belongs to the Special Issue Climate-Resilient Crops: Mechanisms of Plant Stress Tolerance)
  • Article
  • Open Access
42 Citations
7,379 Views
15 Pages

Bitter Melon (Momordica charantia L.) Rootstock Improves the Heat Tolerance of Cucumber by Regulating Photosynthetic and Antioxidant Defense Pathways

  • Mei-Qi Tao,
  • Mohammad Shah Jahan,
  • Kun Hou,
  • Sheng Shu and ,
  • Yu Wang,
  • Jin Sun and
  • Shi-Rong Guo
  • + 2 authors+ 0 author

29 May 2020

High temperature is considered a critical abiotic stressor that is increasing continuously, which is severely affecting plant growth and development. The use of heat-resistant rootstock grafting is a viable technique that is practiced globally to imp...

(This article belongs to the Special Issue Plant Oxidative Stress: Biology, Physiology and Mitigation)