16 Results Found

Pyrazino-phenanthroline ligands are commonly used with transition metals as DNA intercalation agents. Herein, we report the characterization of two commonly utilized pyrazino-phenanthroline ligands, dipyrido[3,2-f:2′,3′-h]quinoxaline (dpq...

Measuring satisfaction can help us understand patients’ expectations and adopt individualized treatment according to their expectations. In the current study, we applied the DPQ (Dental Practice Questionnaire) to analyze the degree of patient s...

The estrogen receptor α (ERα) is an important biological target mediating 17β-estradiol driven breast cancer (BC) development. Aiming to develop innovative drugs against BC, either wild-type or mutated ligand-ERα complexes were...

Herein, we report the synthesis, characterisation, X-ray crystallography, and oxidative DNA binding interactions of the copper artificial metallo-nuclease [Cu(DPQ)₂(NO₃)](NO₃), where DPQ = dipyrido[3,2-f:2′,3′-h]quinoxaline. The cation [C...

Highly active catalyst systems for polymerizing 2,6-dimethylphenol were studied by using aromatic amine ligands and copper(I) chloride. The aromatic amine ligands employed were pyridine, 1-methylimidazole, 2-aminopyridine, 3-aminopyridine, and 4-amin...

Two high-performance Cu catalysts were successfully developed by immobilization of Cu ions in the nanospaces of poly(propylene imine) (PPI) dendrimer and magadiite for the selective C–C coupling of 2,6-dimethylphenol (DMP) to 3,3',5,5'-tetramethyldip...

Three conjugated polymers, in which the electron-donating (D) 5-alkylthiophene-2-yl-substitued benzodithiophene was linked to three different electron-accepting (A) moieties, i.e., benzothiadiazole (BT), diphenylquinoxaline (DPQ), and dibenzophenazin...

Primary tumor targeting is the dominant approach in drug development, while metastasis is the leading cause of cancer death. Therefore, in addition to the cytotoxic activity of a series of Ru(II) polypyridyl complexes of the type [Ru(dip)₂L]²⁺ (dip:...

A highly efficient and sustainable one-pot method for the synthesis of 2,3-diphenylquinoxaline (DPQ) is presented. The reaction employs sodium hypochlorite as an inexpensive and eco-friendly oxidant for the conversion of benzoin, followed by condensa...

Dog breeds are grouped based on scientific agreement, whether for traditional reasons or specific tasks during their domestication. Discrepancies may occur between public views of breed behaviour and actual evidence. This research aims to investigate...

Particle Swarm Optimization (PSO) is a widespread evolutionary technique that has successfully solved diverse optimization problems across various application fields. However, when dealing with more complex optimization problems, PSO can suffer from...

The current results indicated the possible protective actions of 18 kDa mitochondrial translocator protein (TSPO) deletion on TRPM2 stimulation, mitochondrial free ROS (Mito-fROS) and apoptotic harmful actions in the cells of adult retinal pigment ep...

Background: Studies on the effectiveness of community-based health interventions (CBHIs) in improving lifestyle practices among older adults are limited. Objectives: This study evaluated the impact of a CBHI on health knowledge, lifestyle goal attain...

Spermatids are extremely sensitive to genotoxic exposures since during spermiogenesis only error-prone non homologous end joining (NHEJ) repair pathways are available. Hence, genomic damage may accumulate in sperm and be transmitted to the zygote. In...

Several classes of copper complexes are known to induce oxidative DNA damage that mediates cell death. These compounds are potentially useful anticancer agents and detailed investigation can reveal the mode of DNA interaction, binding strength, and t...

Human neuroblastoma SH-SY5Y cells are a widely-used human neuronal cell model in the study of neurodegeneration. A recent study shows that, 1-methyl-4-phenylpyridine ion (MPP), which selectively causes dopaminergic neuronal death leading to Parkinson...