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10 Results Found

  • Article
  • Open Access
5 Citations
2,769 Views
12 Pages

Dehydrated Human Amnion-Chorion Membrane Extracts Can Ameliorate Interstitial Cystitis in Rats by Down-Regulating Inflammatory Cytokines and Protein Coding Genes: A Preclinical Study

  • Che-Hsueh Yang,
  • Min-Che Tung,
  • Yi-Sheng Lin,
  • Chao-Yu Hsu and ,
  • Ivan Akhrymuk,
  • Kok-Tong Tan,
  • Yen-Chuan Ou and
  • Chi-Chien Lin
  • + 3 authors+ 0 author

25 October 2022

The study aimed to investigate the therapeutic impact of intravesical instillation of dehydrated human amnion-chorion membrane (HACM) extracts based on the primary pathological feature of interstitial cystitis (IC). We divided 15 female Sprague-Dawle...

(This article belongs to the Section Pharmaceutical Science)
  • Review
  • Open Access
45 Citations
16,342 Views
30 Pages

The Preparation and Clinical Efficacy of Amnion-Derived Membranes: A Review

  • Alison L. Ingraldi,
  • Robert G. Audet and
  • Aaron J. Tabor

20 October 2023

Biological tissues from various anatomical sources have been utilized for tissue transplantation and have developed into an important source of extracellular scaffolding material for regenerative medicine applications. Tissue scaffolds ideally integr...

(This article belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)
  • Article
  • Open Access
4 Citations
3,744 Views
18 Pages

Increased Phosphatase of Regenerating Liver-1 by Placental Stem Cells Promotes Hepatic Regeneration in a Bile-Duct-Ligated Rat Model

  • Jong Ho Choi,
  • Sohae Park,
  • Gi Dae Kim,
  • Jae Yeon Kim and ,
  • Ji Hye Jun,
  • Si Hyun Bae,
  • Soon Koo Baik,
  • Seong-Gyu Hwang and
  • Gi Jin Kim
  • + 4 authors+ 0 author

24 September 2021

Phosphatase of regenerating liver-1 (PRL-1) controls various cellular processes and liver regeneration. However, the roles of PRL-1 in liver regeneration induced by chorionic-plate-derived mesenchymal stem cells (CP-MSCs) transplantation remain unkno...

(This article belongs to the Collection Chronic Inflammation, Oxidative Stress and Adult Stem Cells)
  • Review
  • Open Access
51 Citations
15,719 Views
8 Pages

Human Chorionic Gonadotropin: The Pregnancy Hormone and More

  • Charalampos Theofanakis,
  • Petros Drakakis,
  • Alexandros Besharat and
  • Dimitrios Loutradis

To thoroughly review the uses of human chorionic gonadotropin (hCG) related to the process of reproduction and also assess new, non-traditional theories. Review of the international literature and research studies. hCG and its receptor, LH/CGR, are e...

(This article belongs to the Special Issue hCG—An Endocrine, Regulator of Gestation and Cancer)
  • Review
  • Open Access
9 Citations
5,899 Views
18 Pages

Extraembryonic Mesenchymal Stromal/Stem Cells in Liver Diseases: A Critical Revision of Promising Advanced Therapy Medicinal Products

  • Mohammad Amin Shahrbaf,
  • Masoumeh Nouri,
  • Morteza Zarrabi,
  • Roberto Gramignoli and
  • Massoud Vosough

23 March 2022

Liver disorders have been increasing globally in recent years. These diseases are associated with high morbidity and mortality rates and impose high care costs on the health system. Acute liver failure, chronic and congenital liver diseases, as well...

(This article belongs to the Special Issue Fetal, Perinatal, and Adult-Derived Allogenic Stem Cells for the Treatment of Liver Diseases: A Therapeutic Approach in Support of or as an Alternative to Solid Organ Transplantation)
  • Article
  • Open Access
14 Citations
6,364 Views
19 Pages

Exogenous Gonadotrophin Stimulation Induces Partial Maturation of Human Sertoli Cells in a Testicular Xenotransplantation Model for Fertility Preservation

  • Marsida Hutka,
  • Lee B. Smith,
  • Ellen Goossens,
  • W. Hamish B. Wallace and ,
  • Jan-Bernd Stukenborg and
  • Rod T. Mitchell
  • + 1 author+ 0 author

18 January 2020

The future fertility of prepubertal boys with cancer may be irreversibly compromised by chemotherapy and/or radiotherapy. Successful spermatogenesis has not been achieved following the xenotransplantation of prepubertal human testis tissue, which is...

(This article belongs to the Special Issue Approach to Male Infertility and Induction of Spermatogenesis)
  • Article
  • Open Access
16 Citations
8,607 Views
18 Pages

Cord Blood Plasma and Placental Mesenchymal Stem Cells-Derived Exosomes Increase Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem Cells While Maintaining Their Stemness

  • Rasha S. Teleb,
  • Amal Abdul-Hafez,
  • Amira Othman,
  • Ahmed El-Abd Ahmed and ,
  • Abdelrahman A. Elsaid,
  • Hattan Arif,
  • Ahmed A. Zarea,
  • Mohammed Abdulmageed,
  • Hend Mohamed and
  • Said A. Omar
  • + 13 authors+ 8 authors

7 January 2023

Background: Mesenchymal stem cells (MSCs) have been used for ex vivo expansion of umbilical cord blood (UCB) hematopoietic stem cells (HSCs) to maintain their primitive characters and long-term reconstitution abilities during transplantation. Therape...

(This article belongs to the Special Issue 10th Anniversary of Cells—Advances in Cell Microenvironment)
  • Article
  • Open Access
2 Citations
2,664 Views
18 Pages

Regulation of Immune Checkpoint Antigen CD276 (B7-H3) on Human Placenta-Derived Mesenchymal Stromal Cells in GMP-Compliant Cell Culture Media

  • Bastian Amend,
  • Lea Buttgereit,
  • Tanja Abruzzese,
  • Niklas Harland and ,
  • Harald Abele,
  • Peter Jakubowski,
  • Arnulf Stenzl,
  • Raphael Gorodetsky and
  • Wilhelm K. Aicher
  • + 4 authors+ 0 author

16 November 2023

Therapies utilizing autologous mesenchymal cell delivery are being investigated as anti-inflammatory and regenerative treatments for a broad spectrum of age-related diseases, as well as various chronic and acute pathological conditions. Easily availa...

(This article belongs to the Special Issue Mesenchymal Stem Cells and Their Derived Products in Aging and Diseases)
  • Article
  • Open Access
12 Citations
5,033 Views
20 Pages

Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment

  • Marsida Hutka,
  • Prashant Kadam,
  • Dorien Van Saen,
  • Natalie Z. M. Homer and ,
  • Jaime Onofre,
  • W. Hamish B. Wallace,
  • Lee B. Smith,
  • Jan-Bernd Stukenborg,
  • Ellen Goossens and
  • Rod T. Mitchell
  • + 5 authors+ 0 author

30 September 2020

Survivors of childhood cancer are at risk for long-term treatment-induced health sequelae, including gonadotoxicity and iatrogenic infertility. At present, for prepubertal boys there are no viable clinical options to preserve future reproductive pote...

(This article belongs to the Special Issue Efforts to Mitigate the Toxicity of Cancer Therapeutics)
  • Article
  • Open Access
4 Citations
2,515 Views
8 Pages

First-Trimester Biochemical Serum Markers in Female Kidney Transplant Recipients—The Impact of Graft Function

  • Natalia Mazanowska,
  • Patrycja Jarmużek-Orska,
  • Bronisława Pietrzak,
  • Joanna Pazik and ,
  • Zoulikha Jabiry-Zieniewicz and
  • Przemysław Kosiński
  • + 1 author+ 0 author

Data on serum biochemistry markers as a component of the first-trimester screening test in pregnant kidney graft recipients are limited. In the absence of a separate validated algorithm, biochemical testing is commonly used in the first-trimester scr...