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15 Results Found

  • Article
  • Open Access
29 Citations
5,273 Views
16 Pages

YycH and YycI Regulate Expression of Staphylococcus aureus Autolysins by Activation of WalRK Phosphorylation

  • Mike Gajdiss,
  • Ian R. Monk,
  • Ute Bertsche,
  • Janina Kienemund,
  • Tanja Funk,
  • Alina Dietrich,
  • Michael Hort,
  • Esther Sib,
  • Timothy P. Stinear and
  • Gabriele Bierbaum

Staphylococcus aureus is a facultative pathogen that can encode numerous antibiotic resistance and immune evasion genes and can cause severe infections. Reduced susceptibility to last resort antibiotics such as vancomycin and daptomycin is often asso...

  • Article
  • Open Access
6 Citations
2,539 Views
20 Pages

11 April 2023

The interaction between water and land resources (WALRs) has been further enhanced with the development of human production activities. Evaluating the synergetic development (SD) level of WALRs is conducive to discovering the weakness of comprehensiv...

  • Article
  • Open Access
10 Citations
5,412 Views
17 Pages

Selective Bacteriocins: A Promising Treatment for Staphylococcus aureus Skin Infections Reveals Insights into Resistant Mutants, Vancomycin Resistance, and Cell Wall Alterations

  • Félix Jaumaux,
  • Kenny Petit,
  • Anandi Martin,
  • Hector Rodriguez-Villalobos,
  • Marjorie Vermeersch,
  • David Perez-Morga and
  • Philippe Gabant

The emergence of antibiotic-resistant S. aureus has become a major public health concern, necessitating the discovery of new antimicrobial compounds. Given that the skin microbiome plays a critical role in the host defence against pathogens, the deve...

  • Article
  • Open Access
1 Citations
2,277 Views
16 Pages

WalK(S221P) Mutation Promotes the Production of Staphylococcus aureus Capsules Through an MgrA-Dependent Pathway

  • Zuwen Guo,
  • Huagang Peng,
  • Weilong Shang,
  • Yi Yang,
  • Zhen Hu,
  • Yifan Rao,
  • Xiaonan Huang,
  • Jianxiong Dou,
  • Zihui Xu and
  • Xiancai Rao

Staphylococcus aureus is a vital pathogen causing clinical infections. Capsules are important virulence factors for S. aureus. This study investigates the regulatory mechanisms underlying capsule production in S. aureus. Bacterial strains XN108 and N...

  • Article
  • Open Access
9 Citations
4,294 Views
31 Pages

8 December 2020

Substantial uncertainties are associated with satellite precipitation datasets (SPDs), which are further amplified over complex terrain and diverse climate regions. The current study develops a regional blended precipitation dataset (RBPD) over Pakis...

  • Article
  • Open Access
210 Views
11 Pages

13 February 2026

In this study, CaO-SiO2-Al2O3-MgO-TiO2 slag was used as the research object to simulate the blast furnace ironmaking process. Based on the experimental data, the influences of basicity (R(w(CaO)/w(SiO2))) and the magnesia–alumina ratio (w(MgO)/...

  • Article
  • Open Access
1 Citations
3,240 Views
15 Pages

15 April 2024

Raw material with a high Al2O3 content has led to an increase in the Al2O3 content in blast furnace slag, which has affected the normal operation of a blast furnace. The exergy analysis method is an important method for studying the energy utilizatio...

  • Article
  • Open Access
540 Views
51 Pages

Language Models Are Polyglots: Language Similarity Predicts Cross-Lingual Transfer Learning Performance

  • Juuso Eronen,
  • Michal Ptaszynski,
  • Tomasz Wicherkiewicz,
  • Robert Borges,
  • Katarzyna Janic,
  • Zhenzhen Liu,
  • Tanjim Mahmud and
  • Fumito Masui

Selecting a source language for zero-shot cross-lingual transfer is typically done by intuition or by defaulting to English, despite large performance differences across language pairs. We study whether linguistic similarity can predict transfer perf...

  • Article
  • Open Access
10 Citations
4,237 Views
11 Pages

Total Lung and Lobar Quantitative Assessment Based on Paired Inspiratory–Expiratory Chest CT in Healthy Adults: Correlation with Pulmonary Ventilatory Function

  • Feihong Wu,
  • Leqing Chen,
  • Jia Huang,
  • Wenliang Fan,
  • Jinrong Yang,
  • Xiaohui Zhang,
  • Yang Jin,
  • Fan Yang and
  • Chuansheng Zheng

28 September 2021

Objective: To provide the quantitative volumetric data of the total lung and lobes in inspiration and expiration from healthy adults, and to explore the value of paired inspiratory–expiratory chest CT scan in pulmonary ventilatory function and furthe...

  • Article
  • Open Access
4 Citations
3,993 Views
14 Pages

The Role of Streamside Native Forests on Dissolved Organic Matter in Forested and Agricultural Watersheds in Northwestern Patagonia

  • Constanza Becerra-Rodas,
  • Christian Little,
  • Antonio Lara,
  • Jorge Sandoval,
  • Sebastián Osorio and
  • Jorge Nimptsch

17 July 2019

Streamside native forests are known for their key role in water provision, commonly referred to as buffers that control the input or output of nutrients from terrestrial to aquatic ecosystems (i.e., nitrogen or carbon cycle). In order to assess the f...

  • Article
  • Open Access
196 Views
12 Pages

16 February 2026

In this study, the surface tension of molten slag was measured using the hanging ring method. Based on the ion and molecular coexistence theory (IMCT), an activity prediction model for the CaO-SiO2-MgO-Al2O3-CaF2 slag system was established, and a co...

  • Article
  • Open Access
5 Citations
6,986 Views
12 Pages

Characterization of Alistipes montrealensis sp. nov., Isolated from Human Feces of a Patient with Metastatic Melanoma Treated with Immune Checkpoint Inhibitors

  • Bertrand Routy,
  • Corentin Richard,
  • Myriam Benlaïfaoui,
  • Simon Grandjean Lapierre,
  • Nicholas Armstrong,
  • Afnan Al-Saleh,
  • Mélodie Boko,
  • Maxime Jacq,
  • Ian R. Watson and
  • Khoudia Diop
  • + 4 authors

26 February 2022

Fecal microbiome culturomics of a cancer patient treated with immune checkpoint inhibitors led to the identification of a Gram-negative, rod-shaped, obligate anaerobic, non-motile, non-spore-forming bacterium, designated strain kh20T, which was phylo...

  • Article
  • Open Access
9 Citations
3,120 Views
14 Pages

28 July 2023

Bacterial blight, caused by Xanthomonas arboricola pv. juglandis, is a significant disease affecting walnut production worldwide. Outbreaks are most severe in spring, and closely tied to host phenology and weather conditions. Pathogen infections are...

  • Proceeding Paper
  • Open Access
4 Citations
1,311 Views
5 Pages

10 February 2022

Composition of phytopathogens—causal agents of “black point” was studied in 2018–2019. Investigations were carried out at the Institute of Plant Protection of National Academy of Agrarian Sciences of Ukraine. Seed samples were...

  • Article
  • Open Access
10 Citations
5,435 Views
21 Pages

A Novel Microbial Dysbiosis Index and Intestinal Microbiota-Associated Markers as Tools of Precision Medicine in Inflammatory Bowel Disease Paediatric Patients

  • Francesca Toto,
  • Chiara Marangelo,
  • Matteo Scanu,
  • Paola De Angelis,
  • Sara Isoldi,
  • Maria Teresa Abreu,
  • Salvatore Cucchiara,
  • Laura Stronati,
  • Federica Del Chierico and
  • Lorenza Putignani

5 September 2024

Recent evidence indicates that the gut microbiota (GM) has a significant impact on the inflammatory bowel disease (IBD) progression. Our aim was to investigate the GM profiles, the Microbial Dysbiosis Index (MDI) and the intestinal microbiota-associa...