- Article
Candida antarctica Lipase A-Based Enantiorecognition of a Highly Strained 4-Dibenzocyclooctynol (DIBO) Used for PET Imaging
- Saija Sirén,
- Käthe M. Dahlström,
- Rakesh Puttreddy,
- Kari Rissanen,
- Tiina A. Salminen,
- Mika Scheinin,
- Xiang-Guo Li and
- Arto Liljeblad
The enantiomers of aromatic 4-dibenzocyclooctynol (DIBO), used for radiolabeling and subsequent conjugation of biomolecules to form radioligands for positron emission tomography (PET), were separated by kinetic resolution using lipase A from Candida...