Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanoparticle-Mediated Targeted Drug Delivery Systems submission deadline 20 Sep 2025 | 9 articles | Viewed by 12772 | Submission Open
Keywords: drug delivery system; nanodelivery system; nanoparticle; receptor-mediated endocytosis/transcytosis; enhanced permeability and retention effect (EPR effect); cancer therapy; central nervous system disease therapy; liposomes; exosomes; RNA delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
3D Printing in Personalized Drug Delivery submission deadline 20 Sep 2025 | 1 articles | Viewed by 980 | Submission Open
Keywords: 3D printing; personalized medicine; precision medicine; on-demand manufacturing; drug delivery systems; patient-centric formulations; additive manufacturing; controlled release; gastro-retentive and floating dosage forms; multi-drug delivery; regulatory challenges in 3D printing manufacturing
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Optimizing Pharmacokinetics Through Formulation Science and Technology
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 689 | Submission Open
Keywords: formulation development; formulation science; pharmacokinetics; biopharmaceutics; in vitro/in vivo extrapolation/correlation; bioavailability; modified release
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Research on Porphyrin and Related Compounds Used in Photodynamic Anticancer and Antimicrobial Therapy
edited by and Ivana Ratkaj
submission deadline 20 Sep 2025 | Viewed by 513 | Submission Open
Keywords: porphyrins; design; synthesis; and characterization; amphiphilicity/lipophilicity; drug dose and light dose; ROS/singlet oxygen production; anticancer photodynamic therapy; antimicrobial photodynamic therapy; hypoxia; cellular binding/uptake; in vitro and in vivo studies
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Emulsifying Drug Delivery Systems
edited by Lissinda Hester Du Plessis and
submission deadline 20 Sep 2025 | Viewed by 423 | Submission Open
Keywords: characterization; dosage form; lipophilic drug delivery systems; lipophilic drugs; permeability; emulsifying drug delivery systems; self-emulsification; solubility
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Biomaterials for Bone Regeneration submission deadline 20 Sep 2025 | Viewed by 265 | Submission Open
Keywords: bone tissue regeneration; dental biomaterials; growth factors; drug delivery; drug formulation; osteogenic drugs; healing
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Combining Ultrasound and Microbubbles/Nanobubbles for Enhancing the Effects of Cancer Therapies
edited by and
submission deadline 20 Sep 2025 | Viewed by 149 | Submission Open
Keywords: ultrasound; immunotherapy; radiation therapy; chemotherapy; micro/nano-bubble; cancer therapeutics; drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Emerging Trends in Skin Delivery Systems submission deadline 25 Sep 2025 | 4 articles | Viewed by 6276 | Submission Open
Keywords: delivery systems; topical and transdermal delivery; innovative excipients; nanoparticles; skin models
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Development of Nucleic Acid Delivery System
edited by
submission deadline 30 Sep 2025 | 5 articles | Viewed by 26834 | Submission Open
Keywords: nucleic acid delivery system; nonviral vectors; gene delivery; siRNA delivery; gene editing system delivery; mRNA delivery; codelivery of small-molecule drugs and nucleic acids; clinical transformation of nucleic acid delivery systems
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Nanotechnology Therapeutics
edited by
submission deadline 30 Sep 2025 | 9 articles | Viewed by 18550 | Submission Open
Keywords: nanotechnology; cancer treatment; drug delivery systems; diagnostic imaging; personalized medicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Development of Physiologically Based Pharmacokinetic (PBPK) Modeling submission deadline 30 Sep 2025 | 6 articles | Viewed by 13574 | Submission Open
Keywords: physiologically based pharmacokinetic modeling (PBPK); modeling and simulations (M& S); pharmacokinetics; ADME; pharmacometrics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advancing Biologic Drug Development Through Physiologically Based Pharmacokinetic Modelling and Simulations
edited by and Javier Reig Lopez
submission deadline 30 Sep 2025 | 5 articles | Viewed by 6214 | Submission Open
Keywords: monoclonal antibodies; antibody-drug conjugates; bispecific antibodies; PBPK; target-mediated drug disposition; lysosomal degradation; FcRn binding; special populations
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Dosage Form Design and Delivery Therapy for Skin Disorders submission deadline 30 Sep 2025 | 3 articles | Viewed by 5299 | Submission Open
Keywords: skin therapy; skin dosage forms; skin delivery; formulations design; natural agents; polysaccharides; vegetable oils; bioactive compounds; antioxidant activity; anti-inflammatory activity; antimicrobial effect; dosage safety and efficacy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Innovative Drug Delivery Strategies for Targeted Cancer Immunotherapy
edited by Jingjing Sun
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5215 | Submission Open
Keywords: immunomodulatory agents; cancer immunotherapy; drug delivery; nanoparticles; checkpoint inhibitors; nanocarriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Challenges and Future Trends of Nano-Based Drug Delivery System in the Treatment of Bone Diseases
edited by Xiao Lin and Jie Shang
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4173 | Submission Open
Keywords: nano-based drug delivery system; drug delivery particles; controlled release; stimuli-responsive drug delivery system; photodynamics therapy; nanozymes; organic porous materials; osteoporosis; fracture healing; osteoarthritis; bone tissue regeneration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Hot Melt Extrusion Technology submission deadline 30 Sep 2025 | 5 articles | Viewed by 4135 | Submission Open
Keywords: hot melt extrusion; solubility enhancement; amorphous solid dispersion; additive manufacturing; twin screw granulation; continuous manufacturing; lipid-based drug delivery systems; patient-centric dosage forms; fused deposition modeling 3D printing; bioavailability
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Advances in Delivery of Peptides and Proteins
edited by and
submission deadline 30 Sep 2025 | 4 articles | Viewed by 3465 | Submission Open
Keywords: peptide delivery; protein delivery; bioavailability; stability; nanoparticles; encapsulation; controlled release; pharmaceutical innovation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Kinase Inhibitors: Innovative Delivery Strategies and Anticancer Potential submission deadline 30 Sep 2025 | 3 articles | Viewed by 3261 | Submission Open
Keywords: kinase inhibitors; ADME; DMPK; formulation studies; anticancer activity; drug discovery; targeted therapy; drug delivery; innovative delivery platforms
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Regenerative Biomaterials with Plant Derivatives for Skin Wound Therapy submission deadline 30 Sep 2025 | 3 articles | Viewed by 2608 | Submission Open
Keywords: biomaterials; plant derivatives; skin regeneration; wound healing; controlled delivery systems; biocompatibility; bioactivity
(This special issue belongs to the Section Drug Targeting and Design)
Preparation and Development of Amorphous Solid Dispersions
edited by and Szymon Sip
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1839 | Submission Open
Keywords: amorphous solid dispersions; drug solubility enhancement; bioavailability improvement; polymer matrix stabilization; pharmaceutical formulation
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Drug Delivery Systems for Targeted Neurological Therapies
edited by Shahrzad Latifi
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1718 | Submission Open
Keywords: drug delivery; brain; central nervous system; neurological disorders; blood– brain barrier; nanothechnology; nanotherapeutics; brain networks
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biopolymer Materials for Wound Healing, 3rd Edition submission deadline 30 Sep 2025 | 2 articles | Viewed by 1681 | Submission Open
Keywords: biopolymer; wound healing; scaffolds; biomaterials; tissue engineering; regenerative medicine; drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Trends in Gel-Based Drug Delivery Systems
edited by and
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1517 | Submission Open
Keywords: gel-based drug delivery systems; stimuli-responsive gel; thermosensitive gel; pH sensitive gel; self-healing gel; aerogels; hydrogels; in situ gels; microgels; organogels; oleogels; 3D printing; gel patches; mucoadhesive gels; wound dressings; tissue engineering; depot injections; implants; ophthalmic gels; biomaterials; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Customized and Designed Micro- and Nanocarriers for Drug Delivery submission deadline 30 Sep 2025 | 1 articles | Viewed by 1185 | Submission Open
Keywords: carrier; drug delivery system; biotechnology; biological purpose; particles; fibers; nanocarrier; microcarrier
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Application of Stimuli-Sensitive Hydrogel for the Treatment of Human and Animal Diseases
edited by and Elena Giuliano
submission deadline 30 Sep 2025 | 1 articles | Viewed by 975 | Submission Open
Keywords: stimuli-responsive hydrogels; self healing; rheology; injectable systems; smart hydrogels
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Biomaterials for Precise Drug Delivery submission deadline 30 Sep 2025 | 1 articles | Viewed by 949 | Submission Open
Keywords: drug delivery vehicles; theranostic drug delivery systems; stimuli-responsive systems; liposomes; microspheres; oleogels; organogels; emulsion-based drug carriers; core– shell systems with drug delivery functions
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biomaterials and Agents: Pharmaceutical and Biomedical Applications in Dental Research, 2nd Edition submission deadline 30 Sep 2025 | 1 articles | Viewed by 864 | Submission Open
Keywords: biomaterials; pharmaceutical agents; dentifrice and drugs; regeneration/restoration strategy; biomimetics; dental tissue; biomineralization; hybrid interfaces; protective layers and coatings; smart dental materials; bioresponsive biomaterials
(This special issue belongs to the Section Drug Targeting and Design)
Biomaterials and Agents: Pharmaceutical and Biomedical Applications in Dental and Orthopedic Research
edited by and Vukoman R. Jokanović
submission deadline 30 Sep 2025 | 1 articles | Viewed by 811 | Submission Open
Keywords: biomaterials; dental and orthopedic applications; regenerative medicine; nanotechnology; 3D printing; drug delivery systems
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Membrane Transport and Drug Permeation
edited by and Alekha K. Dash
submission deadline 30 Sep 2025 | 1 articles | Viewed by 754 | Submission Open
Keywords: drug permeation; membrane transporter; membrane transport; ABC transporter; targeted delivery; membrane-transport protein; blood-brain barrier; solute carrier; ATP-binding cassette family (ABC) transporters; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Biomaterial-Based Nanoencapsulation Systems for Drug Protection and Controlled Release
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 671 | Submission Open
Keywords: nanostructures; nanoencapsulation; drugs/bioactive compounds; biopolymer materials; controlled release; bioavailability; nanoproducts
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Optimizing Drug Therapy in Kidney Diseases: Effectiveness and Safety
edited by , and Ilona Idasiak-Piechocka
submission deadline 30 Sep 2025 | 1 articles | Viewed by 475 | Submission Open
Keywords: drug– drug interactions; pharmacotherapy of kidney diseases; immunosuppression; drug-induced nephrotoxicity; glomerulonephritis; kidney transplantation; hemodialysis; peritoneal dialysis; vasculitis
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
In Silico Pharmacokinetic and Pharmacodynamic (PK-PD) Modeling submission deadline 30 Sep 2025 | Viewed by 473 | Submission Open
Keywords: physiologically based pharmacokinetics (PBPKs); population pharmacokinetics (PopPKs); quantitative systems pharmacology (QSP); Bayesian modeling; artificial intelligence in PK-PD; in silico bioequivalence; multi-objective optimization; translational pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Biomaterials-Based Drug Delivery Systems in Regenerative Medicine submission deadline 30 Sep 2025 | Viewed by 426 | Submission Open
Keywords: tissue regeneration; drug delivery systems; regenerative medicine; biomaterials; stem cell therapy; gene therapy; nanostructured biomaterials; biomimetic materials; decellularized extracellular matrices
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Development of Skin Barrier Repair Therapy Formulations for Skin Care Purposes submission deadline 30 Sep 2025 | 1 articles | Viewed by 304 | Submission Open
Keywords: skin barrier repair therapy; physiological lipid-based formulations; dermatological formulation development; stratum corneum homeostasis; novel delivery systems in skincare
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Extracellular Matrix and Vesicles as Immunomodulatory Therapeutics
edited by , , William D’Angelo and
submission deadline 30 Sep 2025 | Viewed by 280 | Submission Open
Keywords: extracellular matrix; extracellular vesicles; inflammation; immunomodulation; regenerative medicine; drug delivery; clinical translation
(This special issue belongs to the Section Gene and Cell Therapy)
Biomarker-Guided Drug Delivery Systems and Oral Bioavailability Enhancement
edited by and
submission deadline 30 Sep 2025 | Viewed by 237 | Submission Open
Keywords: biomarker-guided delivery; personalized medicine; oral drug bioavailability; targeted drug formulations; nanocarrier; advanced drug carriers; predictive pharmacokinetics
(This special issue belongs to the Section Biopharmaceutics)
Compounds and Drug Delivery for Diabetes Treatment
edited by and Andile Khathi
submission deadline 30 Sep 2025 | Viewed by 209 | Submission Open
Keywords: diabetes; antidiabetic compounds; delivery systems; glycaemic control; insulin
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Stability in Oral Administration submission deadline 30 Sep 2025 | Viewed by 179 | Submission Open
Keywords: drug stability; oral drug delivery; in vitro assessment; dissolution; oral medication lubricants; nano-formulations; biologics; stability enhancement; real-time stability assessment; drug release kinetics
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Drug Products: Latest Trends in Technical Development and Manufacturing of Parenteral Products
edited by Andrea Allmendinger and Hanns-Christian Mahler
submission deadline 30 Sep 2025 | Viewed by 160 | Submission Open
Keywords: parenteral products; sterile manufacturing; biopharmaceuticals; protein stability; cell and gene therapy; formulation development; aseptic manufacturing; Annex 1; sustainability; device integration; container closure integrity; analytical characterization; primary packaging material; single-use technologies; visual inspection; particulate matter; real-time release; subcutaneous administration
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Challenges and Trends in Geriatric Pharmacotherapy: Pharmacodynamics, Pharmacokinetics, and Personalized Therapeutic Strategies submission deadline 30 Sep 2025 | Viewed by 148 | Submission Open
Keywords: pharmacokinetics; pharmacodynamics; drug– drug interactions; drug monitoring; precision dosing; therapeutic strategies; individualized therapy; personalized medicine
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advanced Computational Tools in Development and Assessment of Dosage Form submission deadline 30 Sep 2025 | Viewed by 145 | Submission Open
Keywords: artificial intelligence; computational tools; advanced imaging in drug development; pharmaceutical analysis; dosage form characterization; pharmaceutical process monitoring
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Cell- and Molecular-Mediated Drug Delivery for Bone and Cartilage Repair
edited by Tiago Lazzaretti Fernandes and Daniela Franco Bueno
submission deadline 30 Sep 2025 | Viewed by 142 | Submission Open
Keywords: drug delivery systems; drug discovery; bone repair; cartilage repair; molecular therapies; cellular approaches; tissue engineering; nanotechnology; stem cell therapy; biomaterials; osteoarthritis; therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Hyaluronic Acid-Based Drug Delivery Systems
edited by and Duy-Thuc Nguyen
submission deadline 30 Sep 2025 | Viewed by 137 | Submission Open
Keywords: hyaluronan; biomaterial; hydrogel; drug delivery system; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanomaterials for Cell Biological and Biomedical Applications
edited by
submission deadline 30 Sep 2025 | Viewed by 125 | Submission Open
Keywords: nanomaterials; drug and gene delivery; regenerative medicine; biomedical nanotechnology; cell-nanomaterial interactions; immuno-nanomedicine; functionalized nanoparticles; biosensors and diagnostics; nano-bio interfaces; translational nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
New Frontiers in Therapies, Diagnostics and Biomedical Engineering of Clay-Based Materials submission deadline 30 Sep 2025 | Viewed by 118 | Submission Open
Keywords: clay and clay minerals; biomedical diagnostics; tissue engineering; controlled drug release; theranostic systems; photodynamic therapy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biocompatible Polymers: Fascinating Materials for Drug Delivery Applications submission deadline 30 Sep 2025 | Viewed by 113 | Submission Open
Keywords: biocompatible polymers; drug delivery systems; polymeric micro- and nanoparticles; controlled and/or targeted drug delivery; biodegradable polymers; smart drug carriers; nanomedicine; biomedical applications; encapsulation efficiency; stimuli-responsive polymers; pharmacokinetics and bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Gastrointestinal Disease: Insights into Drug Delivery and Cellular and Molecular Mechanisms for Therapy submission deadline 30 Sep 2025 | Viewed by 112 | Submission Open
Keywords: gastrointestinal disease; drug delivery; molecular therapy; biological therapy; target therapy; molecular target; biomarkers; GI epithelial cells
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Feature Reviews in Pharmaceutical Technology, Manufacturing and Devices
edited by Thierry Vandamme
submission deadline 30 Sep 2025 | Viewed by 111 | Submission Open
Keywords: pharmaceutical technology; drug manufacturing; nanotechnology; continuous manufacturing; drug delivery devices; 3D printing; artificial intelligence; wearable devices; process optimization
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Innovative Applications of Targeted Nanocarriers and Photodynamic Therapy in the Treatment of Neurological Diseases and Tumors submission deadline 30 Sep 2025 | Viewed by 106 | Submission Open
Keywords: photodynamic therapy; neurological disorders; targeted nanocarriers; brain tumors; Alzheimer’ s disease; nanomedicine; drug delivery; reactive oxygen species; nano-photosensitizers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Excipients in the Design and Development of Pharmaceutical Formulations
edited by Dana Emilia Man and
submission deadline 30 Sep 2025 | Viewed by 103 | Submission Open
Keywords: excipients; pharmaceutical formulation; drug delivery systems; drug stability; bioavailability; personalized medicine
(This special issue belongs to the Section Physical Pharmacy and Formulation)
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