Advances in Nanoparticle-Based Therapeutics: From Extracellular Vesicles to Metal Nanocarriers for Cancer Therapy

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 13

Special Issue Editor


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Guest Editor
Inorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Zografou, Greece
Interests: metal complexes; metallic nanoparticles, hybrid nanoparticles; hyperthermia; bioinorganic chemistry; phototherapy
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Special Issue Information

Dear Colleagues,

Cancer remains one of the most complex and aggressive diseases of our time, demanding smarter, more targeted therapeutic strategies. Over the past decade, two distinct yet increasingly converging fields—extracellular vesicle (EV) biology and metal-based nanotechnology—have opened new frontiers in cancer therapy.

Extracellular vesicles, the body’s natural messengers, have emerged as potent vehicles for drug delivery, capable of transporting therapeutic molecules with high specificity and low immunogenicity. At the same time, engineered metal-based nanocarriers, including gold, silver, and iron oxide nanoparticles, offer tunable platforms with precise control over drug release, imaging, and multifunctional targeting.

This Special Issue explores the dynamic interface between these two approaches. It brings together cutting-edge research that spans from fundamental insights into EV biogenesis and engineering, to the design and functionalization of metal nanocarriers. The goal is to harness the best of both biological precision and material innovation to overcome current limitations in cancer treatment.

By highlighting key advances, challenges, and translational perspectives, this Special Issue aims to spark deeper collaboration across disciplines and drive forward the next generation of smart cancer therapeutics.

Dr. Eleni K. Efthimiadou
Guest Editor

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Keywords

  • nanoparticle
  • extracellular vesicle
  • metal-based nanotechnology
  • drug delivery
  • cancer

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Published Papers

This special issue is now open for submission.
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