Bioactive Molecules for Targeted Cancer Therapy and Delivery Innovations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 795
Special Issue Editors
Interests: targeted therapy; tyrosine kinase inhibitors; anti-cancer drugs; drug design; bioactive heterocycles
Special Issues, Collections and Topics in MDPI journals
Interests: nanomedicine; micromedicines; anticancer therapies; drug delivery; nutraceutical formulations
Special Issue Information
Dear Colleagues,
Cancer remains one of the main causes of mortality worldwide, and offering new, more effective, and safer therapeutic alternatives is a major challenge for the scientific community and pharmaceutical industry. Targeted therapy has allowed the development of new drugs for the treatment of some types of cancer based on the blockade of specific molecular targets such as monoclonal antibodies for aberrant growth factor receptors or inhibitors for overexpressed or mutated enzymes related to carcinogenesis and/or tumor growth. However, these treatments also result in a loss of clinical efficacy owing to various resistance mechanisms. Therefore, a permanent search for new bioactive molecules to overcome these limitations is necessary. On the other hand, innovations in drug delivery are crucial due to the suboptimal physicochemical properties of both traditional and novel anticancer drugs. Furthermore, the specific targeting of anticancer drugs to tumor tissues is essential for enhancing both safety and efficacy. This can be further optimized using specialized drug delivery systems. Consequently, the continuous search for new drug delivery systems remains an ongoing necessity.
Pharmaceutics invites both original articles and reviews that shed light on the challenges and opportunities of new bioactive molecules and innovations on drug delivery as part of strategies for targeted cancer therapy. Topics include design, synthesis, in vitro and in vivo studies of drugs and drug delivery systems. The collection of manuscripts will be published as a Special Issue of the journal.
Dr. Cristian O. Salas
Dr. Felipe Andrés Oyarzún-Ampuero
Guest Editors
Manuscript Submission Information
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Keywords
- bioactive molecules
- targeted therapy
- angiogenesis inhibitors
- signal transduction inhibitors
- nano and micromedicines
- drug delivery
- spatial and temporal drug release
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