Pharmaceutical Nanotechnology for the Treatment of Leishmaniasis and Chagas Diseases
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 376
Special Issue Editors
Interests: nanotechnology; nanoparticles; nanoformulation
Special Issues, Collections and Topics in MDPI journals
Interests: phytomedicines; phytochemistry; nanoformulation of natural products; nanobiotechnology
Special Issue Information
Dear Colleagues,
The World Health Organization (WHO) defines neglected tropical diseases (NTDs) as a diverse group of healthy conditions caused by a variety of pathogens and associated with devastating health, social and economic consequences. NTDs are mainly prevalent among poor communities in tropical areas, although some have a much larger geographical distribution, reaching developed countries. It is estimated that NTDs affect more than 1 billion people, while the number of people requiring NTD interventions (both preventive and curative) is 1.6 billion. Among NTDs, leishmaniasis and Chagas disease are two of the most relevant. Currently, the treatment of both parasite infections is still problematic, where few alternative drugs are available for use in clinical settings, and they present serious concerns such as parasite resistance, debilitating side effects, cost of treatment, the need for hospitalization and/or patient continuous monitoring. Pharmaceutical nanotechnology is being employed to overcast many of the problems associated with the drugs in current use. Nanomedicines are believed to expand drug absorption, improve biodistribution, target selected cells or organs, and reduce side effects and general toxicity, as well as help in the introduction of new drug candidates from biological or synthetic origins.
The aim of this Special Issue of Pharmaceutics is to collect research and review papers related to the application of pharmaceutical nanotechnology tools directed to the treatment of leishmaniasis and Chagas diseases. We welcome articles dealing with all aspects nanotechnology and invite researchers and drug developers to publish their original research or review articles with expert opinions and perspectives in the area of both NTDs.
Prof. Dr. Orlando David Henrique dos Santos
Dr. Gustavo Henrique Bianco de Souza
Dr. Janaína Brandão Seibert
Guest Editors
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Keywords
- nanoformulation
- leishmaniasis
- chagas disease
- nanotechnology
- drug toxicity
- bioavailability
- nanomedicine
- dosage form
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