Pharmaceutical Applications of Vesicle and Nanocarrier Delivery Strategies

Dear Colleagues,

The ever-expanding range of therapeutic approaches to human diseases often requires the important support of innovative and novel technologies for the delivery of each new paradigm to its intended target. In many ways, the development of safe and efficient delivery systems has been equally or even more challenging than the therapeutic entity itself.  Vesicular and nanoparticle formulations have met the needs of many of these therapies, and have even led to the launch of many new drugs to the market.

A prominent recent success has been the culmination of many decades of research to form efficacious lipid nanoparticles such as those used in vaccines. These basic nanoparticle formulations have provided a platform of sorts on which to build other modern therapies. However, as our understanding of cellular targets and the basic biology of delivery has expanded, it has become apparent that further work is needed to design and optimize smart delivery systems for each biological or cellular target. The many competing requirements in each situation continue to drive the development of new types of specialized delivery systems, and to fuel further growth and innovations for the development of new therapies requiring such systems to satisfy unmet medical needs.

We present here a group of contributions from across industry and academia, highlighting recent advances in these delivery strategies.

Dr. Paul Meers
Dr. Patrick L. Ahl
Dr. Shaukat Ali
Guest Editors

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