Applications of Nanotechnology in Veterinary Drug Delivery

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 504

Special Issue Editors

*
E-Mail Website
Guest Editor
Infectious Diseases Department, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania
Interests: veterinary public health; nanotechnology; antibiotic resistance; infectious diseases
* Dipl. ECVPH (PM)

E-Mail Website
Guest Editor
1. FP-BHS—Biomedical and Health Sciences Research Unit, FP-I3ID—Instituto de Investigação, Inovação e Desenvolvimento, Faculty of Health Science, Fernando Pessoa University, 4200-150 Porto, Portugal
2. Associate Laboratory i4HB—Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
3. UCIBIO—Applied Molecular Biosciences Unit, MedTech—Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, 050-313 Porto, Portugal
4. RISE—Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia 296, 4200-150 Porto, Portugal
Interests: bioactive delivery systems; lipid-based nanosystems; hybrid nanosystems; controlled delivery; multifunctional nanosystems
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor Assistant
Infectious Diseases Department, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania
Interests: infectious diseases; veterinary medicine; nanotechnology; antibiotic resistance

Special Issue Information

Dear Colleagues,

The rapid advancement of nanotechnology in recent years has significantly impacted various fields within life sciences. Given that some of these emerging technologies have potential applications in veterinary medicine, this Special Issue aims at fostering innovation in the field through the use of nanotechnology.

Nanotechnology offers promising solutions for overcoming key challenges in veterinary pharmacology, such as improving drug bioavailability, enabling targeted and controlled drug release, and minimizing side effects. Additionally, nanocarriers can enhance the solubility of poorly water-soluble drugs, ensuring more effective treatments across different species. Research on novel nano-based delivery systems, including liposomes, polymeric nanoparticles, and lipid-based carriers, is essential for advancing veterinary therapeutics.

As veterinary nanotechnology is still in its early stages, we encourage the submission of research on the synthesis, characterization, and application of nanotechnology-based drugs in veterinary medicine, while also emphasizing studies on safety, toxicity, environmental impact, cost-effective production, large-scale manufacturing, and regulatory considerations, all from a One Health perspective.

Dr. Constantin Cerbu
Prof. Dr. Ildikó Bácskay
Dr. Carla Martins Lopes
Guest Editors

Dr. Emilia Trif
Guest Editor Assistant

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Keywords

  • nanotechnology
  • veterinary medicine
  • drug delivery

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Published Papers (1 paper)

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Research

16 pages, 2226 KiB  
Article
Design of Geraniol-Loaded Nanocapsules for Use Against Salmonella Infantis: Evaluation in an In Vitro Poultry Model
by Karla S. Garcia-Salazar, Hector J. Leon-Solano, Jesus A. Maguey-Gonzalez, Juan D. Latorre, Raquel López-Arellano, Elvia A. Morales Hipólito, Roberto Díaz-Torres, Miguel Morales Rodríguez, Alma Vázquez-Durán, Guillermo Tellez-Isaias, Abraham Méndez-Albores, Bruno Solis-Cruz and Daniel Hernandez-Patlan
Pharmaceutics 2025, 17(7), 840; https://doi.org/10.3390/pharmaceutics17070840 - 27 Jun 2025
Viewed by 322
Abstract
Background/Objectives: Salmonella Infantis (S. Infantis) is a bacterium that has gained importance in public health over the last decade due to its high pathogenicity and resistance to antibiotics. Therefore, the objective of the present study was to present key considerations [...] Read more.
Background/Objectives: Salmonella Infantis (S. Infantis) is a bacterium that has gained importance in public health over the last decade due to its high pathogenicity and resistance to antibiotics. Therefore, the objective of the present study was to present key considerations for the design and development of geraniol-loaded nanocapsules for its delivery in the drinking water or feed of broiler chickens and to evaluate its potential as an antimicrobial agent against S. Infantis using a standard in vitro microplate assay and a model that simulates the pH and feed conditions of the crop of broiler chickens. Methods: Using a 3k factorial experimental design, geraniol nanocapsule-based formulations were selected, and their antimicrobial activity was evaluated in in vitro models. Results: The results demonstrated that geraniol alone exhibits antimicrobial action against S. Infantis mainly due to its lipophilicity, hydrophobicity and the presence of the hydroxyl group found in its chemical structure, but when formulated in nanocapsular systems, the interaction of its components tends to reduce its antimicrobial action, especially the mixture of Tween 80:Span 80 and Miglyol® 810N. Furthermore, the use of the in vitro model that simulates the crop of broiler chickens demonstrated that the formulation also has interactions with the feed components, completely nullifying the antimicrobial action of geraniol compared to that obtained in the in vitro microplate model. Conclusions: Preformulation studies during the development of nanocapsule-based formulations should be considered for the correct selection of the components of a formulation to ensure its effectiveness, without only considering the physicochemical and stability properties of these as is frequently seen in studies. Full article
(This article belongs to the Special Issue Applications of Nanotechnology in Veterinary Drug Delivery)
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