Next-Generation Antibody-Drug Conjugates (ADCs)
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 5187
Special Issue Editor
Interests: medicinal chemistry; targeted therapy; drug delivery; antibody-drug conjugate; structural molecular biology; nuclear receptor superfamily; cancer; immune disease
Special Issue Information
Dear Colleagues,
I am pleased to invite you to contribute to the Special Issue entitled “Next-Generation Antibody–Drug Conjugates”.
ADCs are an emerging drug class for cancer treatment, with 11 successful FDA-approved ADCs for many indications, including both hematological malignancies and solid tumors. Recent advances, including antibody formats (such as a bispecific antibody), conjugation chemistry, linker technology and novel payloads beyond cytotoxic molecules (such as an immunomodulator), can move ADCs to the next generation.
This Special Issue aims to provide cutting-edge knowledge in the field of ADCs. Original research articles and reviews are welcome. Research topics may include the following (but are not limited to): novel antigens, antibodies including fragments and other formats (e.g., bispecific), conjugation methods, linkers and payloads for ADCs. Papers reporting on basic to translational/(pre)clinical research are welcome. Other submissions that facilitate the development of ADCs are also welcome.
I look forward to receiving your contributions.
Dr. Yasuaki Anami
Guest Editor
Manuscript Submission Information
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Keywords
- antibody–drug conjugate
- bioconjugation
- vancer therapy
- targeted therapy
- bystander effect
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