Therapeutic Potential of Natural Extracts in Cancer Prevention and Treatment

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 55

Special Issue Editors


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Guest Editor
Laboratory "Genome Dynamics and Stability", Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences, Sofia, Bulgaria
Interests: anticancer activity of medicinal and aromatic plants; molecular mechanisms of antitumor action; oncogenetics; nutrigenomics; nanotechnology therapeutic approaches

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Guest Editor
Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel
Interests: acute myeloid leukemia; cell differentiation; vitamin D and its analogs; retinoids; plant-derived bioactive compounds; redox signaling; calcium signaling; cell cycle regulation; apoptosis
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Special Issue Information

Dear Colleagues,

Cancer represents the second leading cause of mortality worldwide despite the extensive efforts and resources directed to combating this disease. Among the major disadvantages of conventional chemotherapy are the severe side effects that could occur as a result of the treatment and development of cancer cells' multidrug resistance. Numerous natural-derived substances are objects of increased scientific interest in searching for novel promising candidates for the development of oncotherapeutics with higher efficiency and lower toxicity for normal cells. Cancer chemoprevention by natural products is a prominent approach for the reduction in cancer morbidity rate via suppression or reversion of tumorigenesis.

The present Special Issue, entitled “Therapeutic Potential of Natural Extracts in Cancer Prevention and Treatment”, focuses on the most recent data on the mechanisms and molecular targets of the anticancer action of extracts from natural sources, alone or in combination, in finding prospective agents for prevention and therapy of neoplasias. We are pleased to invite authors to submit original research papers or review articles for consideration and publication in the Special Issue. Manuscripts related to tolaboratory research on in vitro and in vivo model systems or clinical trials evaluating the anticancer potential of nature-derived extracts are welcome. The knowledge gained from such studies can significantly contribute to  improving life quality and cancer treatment outcomes.

Dr. Zlatina Gospodinova
Prof. Dr. Michael Danilenko
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural products
  • anticancer therapeutic potential
  • cancer chemoprevention
  • mechanism of action and molecular targets
  • preclinical and clinical studies

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Published Papers

This special issue is now open for submission.
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