Dietary Modifications from Benefits to Pathology

Dear Colleagues,

The nutritional values of dietary products are not only the amount of calories and the content of particular ingredients, but also their influence on metabolic pathways or genetic predisposition to diseases. Elimination diets in many pathologies such as phenylketonuria and celiac disease illustrate the huge benefits of proper nourishment. Carbohydrate and lipid metabolisms as well as immunological condition disturbances are involved in the pathophysiology of many civilization diseases, such as diabetes, cardiovascular disease, and cancer. This knowledge has made it possible to create animal models of diseases such as insulin resistance caused by a high-lipid diet. For this reason, there are strict recommendations to follow a proper diet in particular pathologies. Moreover, diets with extreme levels of additives or the overconsumption of dietary supplements—especially those of poor quality—may induce organ dysfunction and degeneration. However, some evidence in the literature suggests that the supplementation of proteins, minerals, vitamins, antioxidants, or pre/probiotics etc. in products, specifically compounds obtained from natural sources, can improve health and support treatment. Poor knowledge about the interaction of drugs and dietary products may worsen the health condition of organisms. Most diets or dietary modifications are not scientifically justified. Diet support based on well-performed diagnostic processes and the examined mechanisms of action of nutritional products may meet the criteria of personalized care. Basic, preclinical, and clinical studies should be used to show how diet, products, and natural substances influence living organisms in health and disease.

We invite researchers and clinicians to submit their relevant scientific work, either original articles or reviews, to this Special Issue of Nutrients entitled “Dietary Modification from Benefits to Pathology”.

We look forward to your active participation.

Prof. Dr. Halina Car
Guest Editor

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