Gut Microbiota in Kidney Disease: Potential Mechanisms and Therapeutic Strategies

Dear Colleagues,

Chronic kidney disease (CKD) is expected to become one of the leading causes of death worldwide due to a lack of access to appropriate methods for diagnosing and treating kidney disease. As a chronic disease, it inevitably leads to a deterioration in the patient's quality of life and malnutrition.

Intestinal microflora has been associated with the development of obesity, metabolic syndrome, and the onset of type 2 diabetes. Untreated diabetes may lead to impaired kidney function. A promising approach to diabetes-related diseases focuses on modulating the intestinal microflora using prebiotics, probiotics, synbiotics, and transplantation of fecal microorganisms. Therefore, in this Special Issue, we focus on the role of intestinal microflora in chronic kidney disease. Our spectrum of interests also includes other kidney diseases.

Microorganisms may play a role in the pathogenesis and prevention of kidney stones, which is problematic as it facilitates the participation of the intestinal microbiome, the impact of antibiotics, and the role of probiotics. Randall's plaques are considered a source of calcium oxalate stone formation. However, the microbiome, including nanobacteria, urease-producing bacteria, and intestinal microflora, influence urological health. Therefore, we invite articles investigating the broadly understood impact of the microbiome, both negative and positive, on the course of diseases related to kidney dysfunction.

Dr. Karolina Kędzierska-Kapuza
Prof. Dr. Małgorzata Szczuko
Guest Editors

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