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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Metabolism-Related Biomarkers in Cancer submission deadline 31 Mar 2026 | 5 articles | Viewed by 8198 | Submission Open
Keywords: cancer biomarkers; personalized medicine; metabolism; glucose; amino acid; glutamine; lipid; iron
(This special issue belongs to the Section Bioorganic Chemistry)
Advances in Functional Polymers and Their Applications
edited by and
submission deadline 31 Mar 2026 | 5 articles | Viewed by 7956 | Submission Open
Keywords: functional polymer; polymerization; post-polymerization modification; multi-component; hydrogel; 3D printing; biomaterials; polymer composite; surface and interface
(This special issue belongs to the Section Macromolecular Chemistry)
Heterogeneous Catalysts: From Synthesis to Application
edited by Milan Kralik
submission deadline 31 Mar 2026 | 3 articles | Viewed by 7836 | Submission Open
Keywords: heterogeneous catalyst; acid– base; redox; enzymatic; electrocatalytic; photocatalytic; chemical specialties; characterization methods; mathematical modelling; process design; ecology; safety; economy
(This special issue belongs to the Section Organic Chemistry)
Multifunctional Natural Ingredients in Skin Protection and Care, 2nd Edition submission deadline 31 Mar 2026 | 3 articles | Viewed by 6095 | Submission Open
Keywords: plant extracts; natural compounds; biological activity; cosmetics; antioxidant; anti-aging; skin lightening; UV-protection
(This special issue belongs to the Section Natural Products Chemistry)
Recent Advances in the Toxicology and Safety of Medicinal Plants and Natural Products submission deadline 31 Mar 2026 | 3 articles | Viewed by 5865 | Submission Open
Keywords: toxicity of natural compounds and plant extracts; safety of natural products; drug development; in silico modeling; in vitro study; in vivo study
(This special issue belongs to the Section Natural Products Chemistry)
Quantum Chemical Calculations of Molecular Reaction Processes, 2nd Edition
edited by and Shiro Koseki
submission deadline 31 Mar 2026 | 5 articles | Viewed by 5843 | Submission Open
Keywords: computational chemistry; electronic structure; MO theory; DFT calculation; reaction process; Ab initio molecular dynamics; molecular design
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Extraction, Isolation, and Identification of Bioactive Compounds from Plants submission deadline 31 Mar 2026 | 4 articles | Viewed by 5079 | Submission Open
Keywords: natural products; extraction methods; isolation methods; chromatography; chemical characterization; bioactivity; antioxidant; antimicrobial; antiinflammation; bio-guided assay; biopesticides; biostimulants; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Advances in the Application of Nanoparticles in Antimicrobial Research submission deadline 31 Mar 2026 | 2 articles | Viewed by 4647 | Submission Open
Keywords: nanoparticles; nanobiomaterials; antimicrobial activity; antimicrobial resistance; photodynamic antimicrobial therapy; innovation; drug delivery; sustainability
(This special issue belongs to the Section Nanochemistry)
Molecular Docking in Drug Discovery, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 4631 | Submission Open
Keywords: computer aided drug design; drug discovery; molecular docking; structure– activity relationships; drug design
(This special issue belongs to the Section Medicinal Chemistry)
Exclusive Papers of Editorial Board Members and Invited Scholars in “Materials Chemistry”, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 4 articles | Viewed by 4447 | Submission Open
Keywords: biomaterials; nanomaterials; hybrid materials; core-shell materials; thin films; self-assembling systems; hydrogels; sensors and biosensors
(This special issue belongs to the Section Materials Chemistry)
Porous Carbons for CO2 Adsorption and Capture
edited by and Jinsong Shi
submission deadline 31 Mar 2026 | 4 articles | Viewed by 4237 | Submission Open
Keywords: porous carbons; carbon nanotubes; graphene oxide; carbon nanomaterials; activated carbons; adsorbents; CO2 adsorption; CO2 capture; physisorption; chemical activation; physical activation; surface functionalization; pore structure design; carbon doping; nitrogen doping; CO2 capture efficiency; CO2 selectivity; direct air capture (DAC); CO2 storage; industrial CO2 capture; carbon capture and utilization (CCU); CO2 adsorption mechanisms; adsorption kinetics; sustainable materials; adsorbent regeneration; machine learning in material design
(This special issue belongs to the Section Materials Chemistry)
Chromatography—The Ultimate Analytical Tool, 3rd Edition submission deadline 31 Mar 2026 | 3 articles | Viewed by 3878 | Submission Open
Keywords: chromatography; high-performance liquid chromatography; ultra-high-performance liquid chromatography; gas chromatography; two-dimensional gas chromatography; two-dimensional liquid chromatography; paper chromatography; liquid chromatography; preparative chromatography; supercritical fluid chromatography; thin-layer chromatography
(This special issue belongs to the Section Analytical Chemistry)
Essential Oils: Chemical Composition, Bioactive, and Application
edited by and Nai-Wen Tsao
submission deadline 31 Mar 2026 | 2 articles | Viewed by 3601 | Submission Open
Keywords: essential oils; chemical constituents; biological activities; extraction methods; analytical chemistry; therapeutic effects; antimicrobial activity; drug delivery
(This special issue belongs to the Section Natural Products Chemistry)
Application of Analytical Chemistry in Food Science submission deadline 31 Mar 2026 | 3 articles | Viewed by 3432 | Submission Open
Keywords: analytical chemistry; food safety; food authenticity; food contaminants; spectroscopic methods; chromatographic techniques; advanced sample preparation; sustainability in food analysis
(This special issue belongs to the Section Food Chemistry)
Recent Experimental and Theoretical Advances of Corrosion Protection
edited by , Miguel Castro, Guillermo E. Negrón-Silva and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 3426 | Submission Open
Keywords: electrochemical techniques; synthesis of corrosion inhibitors; molecular dynamics; quantum theoretical modelling; coatings
(This special issue belongs to the Section Electrochemistry)
Advanced Chemical Innovations for Sustainable Water and Wastewater Treatment
edited by Mohammed J.K. Bashir
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2893 | Submission Open
Keywords: advanced oxidation processes; catalytic degradation; nanomaterials; green chemistry; pollutant mineralization; ionic liquid applications; smart adsorbents
(This special issue belongs to the Section Applied Chemistry)
30th Anniversary of the MOF Concept
edited by and
submission deadline 31 Mar 2026 | 4 articles | Viewed by 2542 | Submission Open
Keywords: metal– organic frameworks; gas storage and separation; catalysis; drug delivery; sensing and detection; energy applications
(This special issue belongs to the Section Organometallic Chemistry)
Exploring the Applications of Chromatographic Methods in Material Analysis
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2471 | Submission Open
Keywords: surface energy; adsorption; Lewis’ s acid– base parameters; materials and nanomaterials; biomaterials; drugs; pharmaceuticals; carbon fibers; oxides; metals; polymers; copolymers; composites; crystals; plasticizers; explosives; nanoenergetic materials; technology; thermodynamics
(This special issue belongs to the Section Materials Chemistry)
Feature Papers in Organic Chemistry—Third Edition submission deadline 31 Mar 2026 | 5 articles | Viewed by 2274 | Submission Open
Keywords: organic synthesis; organic chemistry research; synthesis methods; theoretical study; reaction mechanisms; catalysis
(This special issue belongs to the Section Organic Chemistry)
Nano and Micro Materials in Green Chemistry
edited by Ruijin Yu
submission deadline 31 Mar 2026 | 3 articles | Viewed by 2200 | Submission Open
Keywords: green chemistry; biosynthesis and green synthesis; nanomaterials and micro-materials; biohybrid materials; nanostructured electrodes; chemical sustainability assessment
(This special issue belongs to the Section Materials Chemistry)
Biologically Active Compounds in Functional Foods submission deadline 31 Mar 2026 | 2 articles | Viewed by 2082 | Submission Open
Keywords: functional foods; bioactive compounds; vitamins; antioxidants; phenolics; functional ingredients; functional properties; fortified foods; enriched foods; food chemistry; bioavailability; food matrix
(This special issue belongs to the Section Food Chemistry)
Trends of Drug Synthesis in Medicinal Chemistry
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 2021 | Submission Open
Keywords: drug synthesis; anticancer agents; antimicrobial resistance; green chemistry; AI-driven design; targeted delivery systems; continuous-flow technology; structure– activity optimization; multidisciplinary collaboration
(This special issue belongs to the Section Medicinal Chemistry)
Graphene and Graphene-Related Materials for Energy and Environment: Synthesis and Application submission deadline 31 Mar 2026 | 1 articles | Viewed by 2013 | Submission Open
Keywords: graphene; graphene-related materials; energy applications; fuel cells; capacitors; photocatalysis; adsorption
(This special issue belongs to the Section Materials Chemistry)
Discovery and Development of Anti-Cancer Drugs: From Signalling Pathways to Molecular Mechanisms
edited by and Lívia Bitencourt Pascoal
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1862 | Submission Open
Keywords: discovery of small-molecule inhibitors targeting oncogenic kinases and transcription factors; mechanisms of action and resistance for current and emerging cancer drugs; targeting DNA damage response pathways (e.g.; PARP; ATR; ATM inhibitors); molecular crosstalk between tumor cells and the immune system; role of epigenetics in cancer drug resistance and sensitivity; tumor metabolism as a therapeutic target in Immunochemistry; structure-based drug design and virtual screening; antibody– drug conjugates and novel biologic therapeutics; RNA-targeting therapeutics and mRNA-based cancer vaccines; advances in PROTACs and targeted protein degradation; application of AI and computational chemical biology in drug discovery
(This special issue belongs to the Section Chemical Biology)
A New Perspective on the Determination and Removal of Pollutants in the Environment, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1702 | Submission Open
Keywords: organic pollutants; toxic metals; wastewater; natural environment; determination methods; phytoremediation; adsorption; microplastic; toxicity; environmental risk
(This special issue belongs to the Section Green Chemistry)
Bioactive Metabolites from Marine Invertebrates and Their Associated Microorganisms—in Celebration of Professors Longmei Zeng and Jingyu Su’s 95th Birthday
edited by , and Shihai Xu
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1494 | Submission Open
Keywords: marine organisms; bioactive metabolites; marine invertebrates and their associated microorganisms
(This special issue belongs to the Section Natural Products Chemistry)
Novel Nanomaterials: Sensing Development and Applications
edited by and
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1488 | Submission Open
Keywords: biosensor; nanomaterials; material design; nanocomposite; sensor; sensor applications
(This special issue belongs to the Section Materials Chemistry)
Advances in Trace Element Analysis: Techniques and Applications
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 1421 | Submission Open
Keywords: trace element analysis; speciation techniques; environmental monitoring; atomic spectrometry; mass spectrometry; chromatography; bioavailability; environmental impact
(This special issue belongs to the Section Analytical Chemistry)
Current Emerging Trends of Extraction and Encapsulation in Food, 2nd Edition submission deadline 31 Mar 2026 | 2 articles | Viewed by 1406 | Submission Open
Keywords: extraction; encapsulation; drying; emulsion; targeted delivery; stability; bioactive compounds; nonthermal technologies; bioavailability; functional foods
(This special issue belongs to the Section Food Chemistry)
Bioactive Compounds in Plants: Extraction and Application submission deadline 31 Mar 2026 | 2 articles | Viewed by 1312 | Submission Open
Keywords: bioactive compounds; extraction; biological activities
(This special issue belongs to the Section Natural Products Chemistry)
NMR and MRI in Materials Analysis: Opportunities and Challenges
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1300 | Submission Open
Keywords: molecular dynamics and transport phenomena in polymers; hardening reactions in materials; magnetic resonance in analysis of pharmaceutical products; contrast agents; chemistry of wood and its products; thermal and other types of processing of foods; electrochemistry and transport phenomena in batteries and other energy storage devices
Recent Progress in Environmental Analytical Chemistry submission deadline 31 Mar 2026 | 1 articles | Viewed by 1153 | Submission Open
Keywords: environmental monitoring; water; air and soil pollution; pollution analysis; environmental toxicity; analytical chemistry; chemometrics; method development for analysis of environmental compartments; method validation
(This special issue belongs to the Section Analytical Chemistry)
Photo- and Sonodynamic Antimicrobial and Anticancer Compounds submission deadline 31 Mar 2026 | 2 articles | Viewed by 1076 | Submission Open
Keywords: photosensitizers; sonosensitizers; photodynamic treatment; sonodynamic treatment; antimicrobials; anticancer treatment
(This special issue belongs to the Section Medicinal Chemistry)
Applications of Bioactive Ingredients in Grape By-products
edited by and Yavor Lukanov Ivanov
submission deadline 31 Mar 2026 | 1 articles | Viewed by 917 | Submission Open
Keywords: bioactive compounds; grape seeds; skins; and pomace; biological activity; application; medicine; cosmetics; pharmacy; food industry
(This special issue belongs to the Section Food Chemistry)
Biobased Functional Materials for Sustainable Food Packaging and Preservation submission deadline 31 Mar 2026 | 1 articles | Viewed by 886 | Submission Open
Keywords: edible films; active packaging; intelligent packaging; edible coatings; sustainable packaging; food quality
(This special issue belongs to the Section Food Chemistry)
Small Molecules Targeting Age-Related Diseases
edited by and Marco Lessi
submission deadline 31 Mar 2026 | 1 articles | Viewed by 825 | Submission Open
Keywords: age-related diseases; small molecules; cardiovascular diseases; neurodegenerative diseases; metabolic disorders
(This special issue belongs to the Section Medicinal Chemistry)
Photocatalysis for Organic Pollutants Degradation
edited by and
submission deadline 31 Mar 2026 | 1 articles | Viewed by 726 | Submission Open
Keywords: photocatalytic degradation of organic pollutants in waters; design and preparation of photocatalyst; homo- and heterogeneous photo-catalyzed process; intermediate fragments and intermediate organic pollutants; reactive oxygen species (ROS)
(This special issue belongs to the Section Photochemistry)
Novel Nanomaterials for Pollution Control and Environmental Remediation submission deadline 31 Mar 2026 | 1 articles | Viewed by 703 | Submission Open
Keywords: functional nanomaterials; environmental pollution; remediation technologies; heavy metals removal; organic pollutants; emerging contaminants; pollution control
(This special issue belongs to the Section Green Chemistry)
Stable Isotope Techniques Across Chemistry: Methods, Applications, and Perspectives
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 649 | Submission Open
Keywords: stable isotope analysis; compound specific stable isotopes; authenticity; traceability; biogenic isotopic composition; biogeochemistry; geochemistry; molecular archaeometry; environmental chemistry
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in Food Analysis, 2nd Edition submission deadline 31 Mar 2026 | 1 articles | Viewed by 494 | Submission Open
Keywords: food; contaminants; bioactive compounds; chromatography; detection; analytical techniques; analysis
(This special issue belongs to the Section Analytical Chemistry)
Food Chemistry in Europe, 2nd Edition submission deadline 31 Mar 2026 | Viewed by 487 | Submission Open
Keywords: food chemistry; food process; food additives; food analysis; food safety; metabolomics; data analytics
(This special issue belongs to the Section Food Chemistry)
Designing Eco-Friendly Heterogeneous Catalysts for Green Oxidation Reactions submission deadline 31 Mar 2026 | Viewed by 432 | Submission Open
Keywords: catalyst design; catalyst synthesis; sustainability; green chemistry; oxidation
(This special issue belongs to the Section Green Chemistry)
Advances in the Detection and Removal of Organic Residue from Water submission deadline 31 Mar 2026 | 1 articles | Viewed by 404 | Submission Open
Keywords: pollutants; water treatment; sustainable remediation; functionalized materials; adsorption; photocatalysis; advanced oxidation processes; environmental health
(This special issue belongs to the Section Applied Chemistry)
Functional Biomaterials—Structure, Function, and Applications
edited by
submission deadline 31 Mar 2026 | Viewed by 368 | Submission Open
Keywords: biomaterials; tissue regeneration; drug delivery; hierarchical scaffolds; dynamic hydrogels; hybrid nanocomposites; bioactive components; targeted therapeutics; personalized medicine; biomedical engineering
Study on Extraction and Chemical Constituents of Natural Extracts, 2nd Edition submission deadline 31 Mar 2026 | Viewed by 356 | Submission Open
Keywords: pharmacological effects; extracts from plants; fungus; and other living organisms; chemical constituents; isolation
(This special issue belongs to the Section Natural Products Chemistry)
Sol-Gel Derived Nanostructured Materials with Innovative Characteristics and Diversified Applications, 2nd Edition
edited by and Andreia Romeiro
submission deadline 31 Mar 2026 | Viewed by 341 | Submission Open
Keywords: aerogels; nanocomposites; biomaterials; green; life-cycle assessment; functional; modelling; simulation; scale up
(This special issue belongs to the Section Materials Chemistry)
Naturally Inspired Molecules as Inhibitors in Drug Discovery, 2nd Edition submission deadline 31 Mar 2026 | Viewed by 317 | Submission Open
Keywords: natural products; drug design; privileged structures; enzyme inhibition; bioactive compounds; bioinspired compounds; structure– activity relationship (SAR); biological activity; organic synthesis
(This special issue belongs to the Section Medicinal Chemistry)
Polymeric Nano-Based Drug Delivery Systems submission deadline 31 Mar 2026 | Viewed by 316 | Submission Open
Keywords: nanotechnology; polymers; biopolymers; drug delivery; encapsulation; essential oils; blood-brain barrier
(This special issue belongs to the Section Macromolecular Chemistry)
Deep Eutectic Solvents: Design, Characterization, and Applications submission deadline 31 Mar 2026 | Viewed by 298 | Submission Open
Keywords: deep eutectic solvents; solubility enhancement; hydrogen bonding interactions; computational chemistry; thermodynamic modeling; gas capture (CO2; SO2; HCl); pharmaceutical solubilization; structure– property relationships
(This special issue belongs to the Section Applied Chemistry)
Synthesis and Application of 1,2,3-Triazole Derivatives
edited by and
submission deadline 31 Mar 2026 | Viewed by 263 | Submission Open
Keywords: 1; 2; 3-triazoles; synthesis; modification; transannulation; application
(This special issue belongs to the Section Organic Chemistry)
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