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Trends of Drug Synthesis in Medicinal Chemistry

This special issue belongs to the section “Medicinal Chemistry“.

Special Issue Information

Dear Colleagues,

This Special Issue highlights cutting-edge advances in synthetic methodologies across anticancer, antimicrobial, antiviral, anti-inflammatory, cardiovascular, and endocrine therapeutics. With the rise of targeted drug design, green chemistry, and AI platforms redefine oncology treatment, novel small-molecule protease inhibitors combat drug-resistant pathogens, and continuous-flow systems enhance scalable production. We invite contributions exploring catalytic asymmetric synthesis, bioorthogonal chemistry, and computational modeling applications, emphasizing their roles in improving drug efficacy, sustainability, and clinical translation. This collection aims to bridge interdisciplinary insights from organic chemistry, pharmacology, and engineering, fostering discussions on next-generation synthesis paradigms for global health challenges.

Dr. Cheng-Hua Jin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • drug synthesis
  • anticancer agents
  • antimicrobial resistance
  • green chemistry
  • AI-driven design
  • targeted delivery systems
  • continuous-flow technology
  • structure–activity optimization
  • multidisciplinary collaboration

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Molecules - ISSN 1420-3049