Trends of Drug Synthesis in Medicinal Chemistry

Dear Colleagues,

This Special Issue highlights cutting-edge advances in synthetic methodologies across anticancer, antimicrobial, antiviral, anti-inflammatory, cardiovascular, and endocrine therapeutics. With the rise of targeted drug design, green chemistry, and AI platforms redefine oncology treatment, novel small-molecule protease inhibitors combat drug-resistant pathogens, and continuous-flow systems enhance scalable production. We invite contributions exploring catalytic asymmetric synthesis, bioorthogonal chemistry, and computational modeling applications, emphasizing their roles in improving drug efficacy, sustainability, and clinical translation. This collection aims to bridge interdisciplinary insights from organic chemistry, pharmacology, and engineering, fostering discussions on next-generation synthesis paradigms for global health challenges.

Dr. Cheng-Hua Jin
Guest Editor

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