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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Exclusive Feature Papers in Natural Products Chemistry, 3rd Edition submission deadline 15 Aug 2026 | 5 articles | Viewed by 6179
Keywords: natural products; plant secondary metabolism; phytochemical analysis; nutrients and bioactive compounds; bioaccessibility and bioavailability; antioxidant; anti-inflammatory; anticancer
(This special issue belongs to the Section Natural Products Chemistry)
Emerging Research in Perovskite Solar Cells submission deadline 15 Aug 2026 | 1 articles | Viewed by 637
Keywords: perovskite thin films; rigid and flexible perovskite solar cells; 2D/3D, Pb-free, Sn-based, and low/wide-bandgap perovskites; advanced characterization techniques for perovskite materials, thin films, and solar cells; single and tandem perovskite solar cells; synthesis of low-cost and efficient ETLs, HTLs, and electrodes for perovskite devices; chemical approaches for perovskite solar cell stability and reproducibility issues; chemical passivation, surface chemistry, and interface engineering strategies; novel device architectures, device physics, and commercialization aspects; modeling/simulations (DFT, MD, AMPS-1D, Gpvdm, Setfos, SilVACO TCAD, SCAPS-1D, etc.).
(This special issue belongs to the Section Materials Chemistry)
Chromatographic Characterization of Food Using Analytical Methods
edited by
submission deadline 15 Aug 2026 | Viewed by 367
Keywords: food analysis; chromatography; gas chromatography; high-performance liquid chromatography (HPLC); sample preparation (SPE, SPME, derivatization); mass spectrometry; chemometrics; food authenticity and adulteration; green analytical chemistry; artificial intelligence
(This special issue belongs to the Section Food Chemistry)
Next-Generation Nanomaterials for Water Treatment: From Design to Application
edited by Haisheng Tao
submission deadline 15 Aug 2026 | Viewed by 292
Keywords: rational design; characterization; structure-property relationship; functional nanomaterials; contaminant removal; water purification
(This special issue belongs to the Section Materials Chemistry)
Advances in Physical Chemistry: From Theory to Applications
edited by
submission deadline 15 Aug 2026 | Viewed by 274
Keywords: electronic-structure theory; ultrafast spectroscopy; AI-driven modelling; energy-carrier dynamics; machine learning; medical physical chemistry; commercialization of physical chemistry
(This special issue belongs to the Section Physical Chemistry)
Functional Evaluation of Bioactive Compounds from Natural Sources, 2nd Edition submission deadline 16 Aug 2026 | 14 articles | Viewed by 34709 | Submission Open
Keywords: bioactive compounds; natural sources; functional evaluation; biological activities; health benefits; mechanisms of action; bioactivity; phytochemicals
(This special issue belongs to the Section Natural Products Chemistry)
Graphene and Graphene-Related Materials for Energy and Environment: Synthesis and Application submission deadline 16 Aug 2026 | 4 articles | Viewed by 4682 | Submission Open
Keywords: graphene; graphene-related materials; energy applications; fuel cells; capacitors; photocatalysis; adsorption
(This special issue belongs to the Section Materials Chemistry)
Molecular Interactions Between Biomolecules and Combustion-Derived Air Pollutants: Implications for Human Health and Disease
edited by
submission deadline 21 Aug 2026 | Viewed by 191 | Submission Open
Keywords: air pollution; biofuel; combustion emissions; protein–pollutant interactions; DNA adducts; QSAR modeling; computational toxicology; oxidative stress; molecular mechanisms; disease pathogenesis
(This special issue belongs to the Section Chemical Biology)
Analysis of Natural Volatile Organic Compounds (NVOCs)
edited by
submission deadline 30 Aug 2026 | 5 articles | Viewed by 6466 | Submission Open
Keywords: volatile organic compounds; essential oils; headspace; terpene, norisoporenoid and phenylpropane derivatives; aliphatic compounds; gas chromatography
(This special issue belongs to the Section Flavours and Fragrances)
Application of Mass Spectrometry Techniques in Analytical Chemistry
edited by Xiqing Bian and
submission deadline 30 Aug 2026 | 4 articles | Viewed by 2968 | Submission Open
Keywords: mass spectrometry; analytical chemistry; omics analysis; pharmaceutical analysis; food safety; clinical diagnostics
(This special issue belongs to the Section Analytical Chemistry)
Harnessing Peptides and Peptidomimetics in Modern Drug Discovery
edited by
submission deadline 30 Aug 2026 | 1 articles | Viewed by 1236 | Submission Open
Keywords: peptide synthesis; peptidomimetics; cyclic peptides; peptide therapeutics; peptide drug discovery; modified peptides; bioactive peptides
(This special issue belongs to the Section Medicinal Chemistry)
Porphyrin-Based Molecules: From Synthesis to Structure–Activity Relationships and Applications
edited by Prashanth K. Poddutoori
submission deadline 30 Aug 2026 | 1 articles | Viewed by 972 | Submission Open
Keywords: porphyrin; phthalocyanine; corrole; borondipyrromethane; synthesis; photophysics; electrochemistry; energy transfer; electron transfer; solar energy conversion; photodynamic therapy; molecular electronics, photonics, and catalysis
(This special issue belongs to the Section Organic Chemistry)
Droplet Chemistry: Superwetting, Evaporation and Applications submission deadline 30 Aug 2026 | Viewed by 440 | Submission Open
Keywords: superwetting; evaporation control; droplet manipulation; evaporation dynamics
(This special issue belongs to the Section Physical Chemistry)
Bioproducts for Health, 4th Edition submission deadline 31 Aug 2026 | 6 articles | Viewed by 16592 | Submission Open
Keywords: bioactive compounds; health applications; natural sources; purification; downstream processing; sustainability
(This special issue belongs to the Section Natural Products Chemistry)
Biobased Materials for Tissue Engineering submission deadline 31 Aug 2026 | 3 articles | Viewed by 14474 | Submission Open
Keywords: biobased materials; biopolymers; scaffold development; tissue engineering; regenerative therapy; cell culture; stem cell therapy; drug delivery; hydrogels; wound dressing
(This special issue belongs to the Section Materials Chemistry)
Chemical Composition and Biological Activity of Essential Oils and Other Extracts: From Extraction to Application, Second Edition
edited by
submission deadline 31 Aug 2026 | 10 articles | Viewed by 10917 | Submission Open
Keywords: medicinal and aromatica plant resources; plant extracts; essential oils; secondary metabolites; chromatography; mass spectrometry; bioactivity; synergism; application
(This special issue belongs to the Section Natural Products Chemistry)
Biological Evaluation of Plant Extracts, 2nd Edition
edited by
submission deadline 31 Aug 2026 | 13 articles | Viewed by 10381 | Submission Open
Keywords: medicinal plants; phytochemistry; phytopharmacology; metabolomics; proteomics; cell signalization
(This special issue belongs to the Section Natural Products Chemistry)
30th Anniversary of Molecules—Recent Advances in Green Chemistry
edited by
submission deadline 31 Aug 2026 | 9 articles | Viewed by 9505 | Submission Open
Keywords: green catalysts; green extraction and processing; chemistry based on natural products; bio-based solvents with sub- and super-critical fluids; microwave and ultrasound; organic reaction in green solvents; bioconversion of biomass and sustainable biomaterials; creating fine chemicals and polymers from renewable resources; green nanotechnology; green analytical chemistry; green degradation process
(This special issue belongs to the Section Green Chemistry)
Antioxidant, Anti-Inflammatory Activities and Skin Protective Potential of Extractions from Natural Plants
edited by Gerardo Magela Vieira-Júnior and
submission deadline 31 Aug 2026 | 6 articles | Viewed by 8187 | Submission Open
Keywords: antioxidants; anti-inflammatory; skin protection; phenolic compounds; extracts derived from plants; natural products
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis of Nanomaterials and Their Applications in Biomedicine—2nd Edition
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 7188 | Submission Open
Keywords: nanomaterials; biomaterials; synthesis; characterization; diagnosis; treatment; cytotoxicity; biocompatibility
(This special issue belongs to the Section Materials Chemistry)
Molecular Insights into Bioluminescence and Chemiluminescence
edited by
submission deadline 31 Aug 2026 | 4 articles | Viewed by 6577 | Submission Open
Keywords: bioluminescence; chemiluminescence; chemical mechanism; luminescence; photophysics; photochemical processes; bioluminescent enzymes; luminescent sensing and imaging
(This special issue belongs to the Section Photochemistry)
Discovery of Microbial Natural Products
edited by and
submission deadline 31 Aug 2026 | 3 articles | Viewed by 6469 | Submission Open
Keywords: microbial natural products; determination of structure; microorganism; drug candidate; bioactive secondary metabolites; microbial biotechnology
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Application of Natural Compounds in Skin Repair and Regenerative Medicine submission deadline 31 Aug 2026 | 5 articles | Viewed by 5836 | Submission Open
Keywords: angiogenesis; anti-inflammatory agents; antioxidants; drug delivery systems; growth factors; natural compounds; skin regeneration; tissue engineering; wound healing
(This special issue belongs to the Section Applied Chemistry)
A New Perspective on the Determination and Removal of Pollutants in the Environment, 2nd Edition
edited by
submission deadline 31 Aug 2026 | 7 articles | Viewed by 5643 | Submission Open
Keywords: organic pollutants; toxic metals; wastewater; natural environment; determination methods; phytoremediation; adsorption; microplastic; toxicity; environmental risk
(This special issue belongs to the Section Green Chemistry)
Emerging Trends in Microextraction Techniques for Bioanalytical Applications submission deadline 31 Aug 2026 | 4 articles | Viewed by 5638 | Submission Open
Keywords: sorbent-based microextraction (i.e., solid phase microextraction (SPME), matrix solid phase dispersion (MSPD), pipette-tip micro solid phase extraction, fabric sorptive phase extraction (FPSE), capsule phase microextraction (CPME), stir bar sorptive extraction (SBSE), etc.); liquid-phase microextraction (dispersive liquid–liquid microextraction, single-drop microextraction, electromembrane extraction, etc.); automation; new materials/sorbents (MOF, COFs, nanomaterials, conductive polymers, magnetic materials, etc.); miniaturization in sample preparation
(This special issue belongs to the Section Analytical Chemistry)
Design and Application Based on Versatile Nano-Composites: Second Edition
edited by
submission deadline 31 Aug 2026 | 4 articles | Viewed by 5161 | Submission Open
Keywords: nanoparticles; nanosheets; composites; preparation; application
(This special issue belongs to the Section Nanochemistry)
Determination of Trace Heavy Metals and Metalloids in Environmental and Food Samples, 3rd Edition submission deadline 31 Aug 2026 | 4 articles | Viewed by 5093 | Submission Open
Keywords: environmental analytical chemistry; food analytical methods; trace heavy metals and metalloids; chemical speciation; instrumental analysis; new analytical methods and techniques; sample pre-treatment; extreme environments; reviews; emerging environmental issues; emerging food issues; food and “novel foods”; insects; climate change and biogeochemical cycles of trace heavy metal(loid)s
(This special issue belongs to the Section Analytical Chemistry)
Functional Materials for Small Molecule Electrocatalysis
edited by , Linlin Li and Qingxue Lai
submission deadline 31 Aug 2026 | 2 articles | Viewed by 5035 | Submission Open
Keywords: electrocatalysis; nanomaterials; electrochemical conversion of H2O; CO2 and N2
(This special issue belongs to the Section Nanochemistry)
Transition Metal Complexes with Bioactive Ligands
edited by
submission deadline 31 Aug 2026 | 4 articles | Viewed by 4885 | Submission Open
Keywords: transition metal complexes; DFT; QTAIM; biological activity; bioactive ligands; crystal structures
(This special issue belongs to the Section Organometallic Chemistry)
Functional Materials: Synthesis Strategies and Environmental Applications
edited by and
submission deadline 31 Aug 2026 | 5 articles | Viewed by 4709 | Submission Open
Keywords: environmental remediation; pollutant removal; materials chemistry; catalytic materials; environmental chemistry
(This special issue belongs to the Section Materials Chemistry)
Advanced Nanotherapeutics: Design, Synthesis and Applications—2nd Edition submission deadline 31 Aug 2026 | 2 articles | Viewed by 4676 | Submission Open
Keywords: nanomedicine; nanodelivery systems; polymer therapeutics; polymer nanoparticles; anticancer nanomaterials; antimicrobial nanoparticles; theranostics
(This special issue belongs to the Section Nanochemistry)
Oxidative Stress and Antioxidants in Degenerative Conditions
edited by Eleni A. Rekka and
submission deadline 31 Aug 2026 | 3 articles | Viewed by 4676 | Submission Open
Keywords: antioxidants; oxidative stress; chronic-degenerative diseases; hormonal imbalance; anti-inflammatory activity; multi-targeting compounds
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Extraction, Characterization and Application of High-Value Compounds submission deadline 31 Aug 2026 | 4 articles | Viewed by 4402 | Submission Open
Keywords: bioactive compounds; green extraction techniques; optimization parameters; by-product valorization; health-promoting properties
(This special issue belongs to the Section Natural Products Chemistry)
Cross-Coupling Strategies for the Synthesis of Functionalized Organic Compounds
edited by Xiaobo Pang and Han-jun Ai
submission deadline 31 Aug 2026 | 2 articles | Viewed by 4309 | Submission Open
Keywords: cross-coupling; transition metal catalysis; palladium catalysis; copper catalysis; nickel catalysis; C–N bond formation; C–C bond formation; photoredox; electrochemistry; organic synthesis; functionalized molecules; catalytic mechanisms; green chemistry
(This special issue belongs to the Section Organic Chemistry)
Molecular Strategies for the Synthesis of Drug-Like Bioactives submission deadline 31 Aug 2026 | 1 articles | Viewed by 4113 | Submission Open
Keywords: drug-like bioactives; synthetic methodologies; green chemistry; multitarget ligands; PROTACs; molecular glues; biocatalysis; scaffold design; late-stage functionalization
(This special issue belongs to the Section Medicinal Chemistry)
Antimicrobial Peptide Assemblies
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 4047 | Submission Open
Keywords: peptides; peptide hybrids; peptide conjugates; self-assembly; stimuli-responsiveness; antimicrobial activity
(This special issue belongs to the Section Chemical Biology)
Bioactive Components From Fungi in the Context of Biomedical Applications
edited by Magdalena Jaszek
submission deadline 31 Aug 2026 | 2 articles | Viewed by 3496 | Submission Open
Keywords: fungal bioactive substances; polysaccharides; phenolic compounds; mushroom extracts; medicinal mushrooms; biomedical applications; functional food
(This special issue belongs to the Section Natural Products Chemistry)
Radiopharmaceutical Chemistry: Developments and Breaks
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 3244 | Submission Open
Keywords: radiopharmaceutical chemistry; organic, peptide, analytical and metal organic radiochemistry; synthesis machines/synthesizer; radioactive labeling; isotopes; human biochemistry; metabolism/metabolites
(This special issue belongs to the Section Medicinal Chemistry)
Natural and Synthetic Bioactive Compounds in Food—Risks and Benefits
edited by
submission deadline 31 Aug 2026 | 4 articles | Viewed by 3043 | Submission Open
Keywords: bioactive compounds; health; safety; effects; toxicology; biology; food; feed
(This special issue belongs to the Section Medicinal Chemistry)
Applications of Solid-Phase Microextraction and Related Techniques, the Second Edition
edited by
submission deadline 31 Aug 2026 | 2 articles | Viewed by 2982 | Submission Open
Keywords: solid-phase microextraction; micriextraction techniques; extraction sorbents; pharmaceutical analysis; forensic analysis; bioanalysis; environmental analysis; food analysis
(This special issue belongs to the Section Analytical Chemistry)
Environmentally Friendly Technologies for Waste Processing and Recovery
edited by and Shuang Zhou
submission deadline 31 Aug 2026 | 2 articles | Viewed by 2837 | Submission Open
Keywords: green waste processing; resource recovery; industrial by-products; impurity removal; waste-to-resource conversion; sustainable materials; circular economy; environmentally friendly technologies
(This special issue belongs to the Section Green Chemistry)
Peptide and Protein Folding submission deadline 31 Aug 2026 | 2 articles | Viewed by 2746 | Submission Open
Keywords: peptide structure and dynamics; disulfide bond formation; folding pathways and intermediates; protein stability and misfolding; machine learning in structural biology
(This special issue belongs to the Section Chemical Biology)
Recent Advances in DNA/Protein Biosensors submission deadline 31 Aug 2026 | 1 articles | Viewed by 2739 | Submission Open
Keywords: biosensors; DNA; RNA; proteins; biomarkers
(This special issue belongs to the Section Analytical Chemistry)
Bioactive Compounds in Foods, Beverages, and By-Products and Their Functional Potential submission deadline 31 Aug 2026 | 2 articles | Viewed by 2622 | Submission Open
Keywords: bioactive compounds in foods, beverages, and/or food by-products; unconventional raw materials as a source of bioactive compounds; bioactive compounds in human health and diseases; bioactive compounds: focus on its mechanism of action; bioavailability of the bioactive compounds; studies (in silico, in vitro, vivo, and clinical) with a focus on bioactive potential; analytical techniques to identify bioactive compounds; trends and advances in bioactive compounds analysis
(This special issue belongs to the Section Food Chemistry)
Natural Bioactive Compounds: Therapeutic Potential in the Management of Chronic Diseases submission deadline 31 Aug 2026 | 1 articles | Viewed by 2618 | Submission Open
Keywords: natural bioactives; phytochemicals; polyphenols; isoprenoids; alkaloids; bioactive lipids and peptides; prebiotics; postbiotics; chronic diseases; non-communicable diseases
(This special issue belongs to the Section Natural Products Chemistry)
Progress in CO2 Storage Materials
edited by and Tianshan Xue
submission deadline 31 Aug 2026 | 1 articles | Viewed by 2539 | Submission Open
Keywords: carbon capture and storage; mineral carbonation; CO2 sorbents; metal-organic frameworks; porous polymers; catalytic conversion
Natural Product-Inspired Drug Discovery: From Molecular Design to Safety and Translational Pharmacology
edited by and Hassan Y. Ebrahim
submission deadline 31 Aug 2026 | 1 articles | Viewed by 2448 | Submission Open
Keywords: metabolism; molecular design; molecular mechanistic pathways; natural products; PKs/PDs; RNA/DNA Sequencing; toxicity/safety
(This special issue belongs to the Section Medicinal Chemistry)
Radiolabeled Nanoparticles: Molecular Design, Targeting, Therapy, and Imaging
edited by Yuichiro Kadonaga and
submission deadline 31 Aug 2026 | 3 articles | Viewed by 2248 | Submission Open
Keywords: synthesis of radiolabeled nanoparticles; biological evaluation of radiolabeled nanoparticles; theranostics; drug delivery; surface modification of nanoparticles; structural analysis; nuclear medicine; organic chemistry; inorganic chemistry
(This special issue belongs to the Section Nanochemistry)
Chiral Nanomaterials: Synthesis, Properties, and Applications
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 2216 | Submission Open
Keywords: chiral nanomaterial; property; synthesis; application
(This special issue belongs to the Section Applied Chemistry)
Modern Application of Cycloaddition Reactions: Experimental and Theoretical Research
edited by and Patricia Perez
submission deadline 31 Aug 2026 | 1 articles | Viewed by 2040 | Submission Open
Keywords: cycloaddition reactions; molecular electron density theory; density functional theory; reaction mechanism; organic synthesis; bioactive compounds; biological activity of heterocyclic compounds
(This special issue belongs to the Section Organic Chemistry)
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