Advances in Application of Natural Compounds in Skin Repair and Regenerative Medicine
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Applied Chemistry".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 2744
Special Issue Editor
Interests: hyaluronan; reactive oxygen species; drugs; antioxidants; biopolymers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleague,
Natural compounds play a crucial role in promoting wound healing and skin regeneration by modulating key cellular and molecular processes involved in tissue repair. Naturally derived molecules, including polysaccharides, peptides, polyphenols, vitamins, and growth factors, can stimulate multiple phases of wound healing, such as hemostasis, inflammation resolution, re-epithelialization, angiogenesis, and extracellular matrix remodeling.
Antioxidant and anti-inflammatory natural compounds help mitigate oxidative stress and chronic inflammation, while antimicrobial natural compounds contribute to infection prevention in both acute and chronic wounds. When incorporated into advanced delivery systems—such as hydrogels, nanofibers, scaffolds, and films—natural compounds can be protected from degradation, precisely targeted, and released in a controlled manner at the wound site, enhancing stability and therapeutic efficacy.
Current research also emphasizes the development of cell-instructive materials incorporating natural compounds that provide biochemical and biophysical cues to guide stem cell recruitment and differentiation, enabling true tissue regeneration rather than simple wound closure. This Special Issue focuses on the sources, mechanisms of action, and delivery strategies of natural compounds for wound healing and skin regeneration, while highlighting current challenges and future directions toward safe, effective, and clinically translatable therapies.
Dr. Katarína Valachová
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- angiogenesis
- anti-inflammatory agents
- antioxidants
- drug delivery systems
- growth factors
- natural compounds
- skin regeneration
- tissue engineering
- wound healing
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
