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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Exploring the Natural Antioxidants in Foods
edited by Ewa Piątkowska, Mariola Drozdowska and Ewelina Piasna-Słupecka
submission deadline 30 Nov 2025 | 4 articles | Viewed by 5978 | Submission Open
Keywords: antioxidants; non-communicable diseases; vegetables; fruit; free radicals
(This special issue belongs to the Section Natural Products Chemistry)
Lipids and Surfactants in Delivery Systems
edited by Agnieszka Lewińska and Marta Domżał-Kędzia
submission deadline 30 Nov 2025 | 4 articles | Viewed by 5935 | Submission Open
Keywords: delivery systems; controlled-release systems; targeted delivery systems; preparation and characterization; surfactant– lipid interactions; lipid and surfactant nanocarriers; bioavailability enhancement; nanotechnology
(This special issue belongs to the Section Nanochemistry)
Synthesis and Crystal Structure of Rare-Earth Metal Compounds
edited by
submission deadline 30 Nov 2025 | 4 articles | Viewed by 5680 | Submission Open
Keywords: synthesis; crystal structure; luminescence; magnetism; catalysts; optical properties
(This special issue belongs to the Section Inorganic Chemistry)
Recent Advances in Supramolecular Chemistry
edited by Wen-Chao Geng
submission deadline 30 Nov 2025 | 5 articles | Viewed by 5431 | Submission Open
Keywords: supramolecular chemistry; molecular recognition; self-assembly; supramolecular materials; macrocycles
(This special issue belongs to the Section Macromolecular Chemistry)
Advances in Green Solvents for Analytical Chemistry: Deep Eutectic Solvents and Biosolvents submission deadline 30 Nov 2025 | 3 articles | Viewed by 4821 | Submission Open
Keywords: eutectic Solvents; biosolvents; green chemistry; microextraction techniques; environmentally friendly methods; green sample preparation; chromatography modifiers; sample preparation
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in Mass Spectrometry Analysis for Medical and Pharmaceutical Applications
edited by Wojciech Piekoszewski
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4216 | Submission Open
Keywords: mass spectrometry (MS); biomarkers; drug metabolism; proteomics; metabolomics; pharmaceutical analysis; personalized medicine; therapeutic drug monitoring
(This special issue belongs to the Section Analytical Chemistry)
Advanced Analytical Tools for Characterization and Quality Control of Food, Drugs, and Natural Active Ingredients, 3rd Edition submission deadline 30 Nov 2025 | 3 articles | Viewed by 4046 | Submission Open
Keywords: authentication; classification; pharmaceutical drugs; food; quality control; natural products; geographical origin; chemometrics
(This special issue belongs to the Section Analytical Chemistry)
Advanced Polymer Nanocomposites for Energy Applications for a Sustainable Environment submission deadline 30 Nov 2025 | 2 articles | Viewed by 3885 | Submission Open
Keywords: polymer nanocomposites; multifunctional materials; heat storage; energy conversion; energy harvesting; thermal management of batteries; characterization; applications
(This special issue belongs to the Section Materials Chemistry)
Bee Products: Recent Progress in Health Benefits Studies, 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 3608 | Submission Open
Keywords: honey bee products; bioactive compounds; biological and phamacological activity; health benefits; side effects of honey bee products
(This special issue belongs to the Section Natural Products Chemistry)
Innovative Materials for Advanced Lithium, Sodium and Zinc Batteries: Design, Synthesis and Application
edited by Ting He
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3332 | Submission Open
Keywords: functional electrode material; electrochemistry; energy storage; Li/Na/Zn-ion battery; aqueous battery
(This special issue belongs to the Section Electrochemistry)
Small Molecule Drug Discovery and Development to Face Neurodegenerative Threads submission deadline 30 Nov 2025 | 3 articles | Viewed by 3184 | Submission Open
Keywords: neurodegenerative diseases; neuroprotection; drug discovery; synthesis of pharmaceutically relevant compounds; isolation and identification of biologically active natural products; in vitro; ex vivo; and in vivo biological evaluation; molecular docking; drug repositioning
(This special issue belongs to the Section Medicinal Chemistry)
Quantum Chemical Calculations of Molecular Reaction Processes, 2nd Edition
edited by and Shiro Koseki
submission deadline 30 Nov 2025 | 4 articles | Viewed by 2881 | Submission Open
Keywords: computational chemistry; electronic structure; MO theory; DFT calculation; reaction process; Ab initio molecular dynamics; molecular design
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Advanced Materials for Photocatalytic and Photoelectrocatalytic Water-Splitting submission deadline 30 Nov 2025 | 2 articles | Viewed by 2783 | Submission Open
Keywords: photocatalysis; photoelectrocatalysis; water splitting; bandgap engineering; semiconductor materials; visible-light-driven catalysis
(This special issue belongs to the Section Materials Chemistry)
Advances in 2D Materials for Electrochemical Applications
edited by Le Li, Dan Zhang and
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2582 | Submission Open
Keywords: electrochemistry; 2D materials and their composites; materials chemistry; energy storage and conversion; batteries; solar cells and electrocatalysis
(This special issue belongs to the Section Electrochemistry)
Extraction and Antioxidant Activity of Bee Products submission deadline 30 Nov 2025 | 2 articles | Viewed by 2529 | Submission Open
Keywords: bee products; extraction; chemical composition; isolation and identification; chromatographic analysis; analytical methods; antioxidants; biologically active compounds
(This special issue belongs to the Section Natural Products Chemistry)
Functional Nanomaterials for Food Safety and Biomedicine Analysis Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2413 | Submission Open
Keywords: functional nanomaterials; biosensors; food safety; biomedicine analysis; disease diagnosis
(This special issue belongs to the Section Applied Chemistry)
Harnessing Nature’s Chemical Diversity: Innovations in Isolation, Identification, and Synthesis
edited by Niko Radulović and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 2373 | Submission Open
Keywords: natural product chemistry; phytochemistry and essential oils; isolation and structural elucidation; chromatographic techniques (GC; HPLC; etc.); mass spectrometry (GC-MS; LC-MS; etc.); NMR spectroscopy; analytical chemistry; synthetic and semi-synthetic methods; bioactive compounds and biological activity; medicinal and aromatic plants; chemotaxonomy; chemical ecology and plant defense mechanisms; biotechnological applications; structure– activity relationships (SAR); biomimetic synthesis
(This special issue belongs to the Section Natural Products Chemistry)
Functional Crystal Materials: Challenges and Opportunities
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2256 | Submission Open
Keywords: functional crystal materials; crystal engineering; structure-property relationship; multi stimulus responsive crystals; artificial intelligence; molecular self-assembly; meso-scale
(This special issue belongs to the Section Materials Chemistry)
Advances in Food Analytical Methods
edited by Yahui Guo
submission deadline 30 Nov 2025 | 3 articles | Viewed by 2215 | Submission Open
Keywords: food analysis; food component; food contaminant; food additive; functional compound; chromatography; mass spectrometry; spectroscopy; biosensor; chemometrics; AI-based approach; food safety; food authenticity; nutritional quality; food traceability
(This special issue belongs to the Section Food Chemistry)
Synthesis and Application of Multifunctional Nanocomposites
edited by , Yao Yuan and Lulu Xu
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2137 | Submission Open
Keywords: nanocomposites; functional materials; molecules; synthesis; characterization
(This special issue belongs to the Section Nanochemistry)
Molecular Insights into Functional Lipids in Food Chemistry
edited by and Siyu Zhang
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1978 | Submission Open
Keywords: structured lipid; synthesis; crystallization; fatty acid; glyceride  
(This special issue belongs to the Section Food Chemistry)
Extraction and Analysis of Natural Products in Food—3rd Edition submission deadline 30 Nov 2025 | 2 articles | Viewed by 1947 | Submission Open
Keywords: natural products; extraction methodologies: green impacts and sustainability  ; separation and purification techniques  ; agri-food byproducts  ; natural bioactive compounds  ; food ingredients  ; industrial application
(This special issue belongs to the Section Natural Products Chemistry)
Metal Complexes: Synthesis, Characterization and Applications submission deadline 30 Nov 2025 | 2 articles | Viewed by 1668 | Submission Open
Keywords: coordination compounds; synthetic strategies; magnetic properties; optical properties; metallodrugs; catalysis
(This special issue belongs to the Section Organometallic Chemistry)
Valorization of Biomass and Waste: Transforming Renewable Resources into High-Value Chemicals and Fuels
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1625 | Submission Open
Keywords: thermochemical; biochemical; and hybrid conversion processes; noncatalytic; catalytic; and biocatalytic valorization pathways; platform chemicals and bio-based polymers from biomass; biofuels production (biodiesel; bioethanol; biogas; etc.); upcycling of agricultural; industrial; and municipal waste; process optimization and scale-up; novel materials derived from renewable or waste sources
(This special issue belongs to the Section Green Chemistry)
Biotechnology and Biomass Valorization
edited by , and Parushi Nargotra
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1544 | Submission Open
Keywords: biomass; conversion; utilization; enzyme; biological; microorganism; fermentation; high value-added product; biofuel; biogas; bioplastic; biochemical material; functional ingredient; bio-based material; metabolic engineering; synthetic biology; biorefining; bioresource; food waste; agricultural by-product; marine biological resource; extraction; purification; life cycle assessment (LCA)
(This special issue belongs to the Section Green Chemistry)
Novel Antimicrobial Molecules Derived from Natural Sources submission deadline 30 Nov 2025 | 1 articles | Viewed by 1491 | Submission Open
Keywords: antibiotics; mechanism of action; plant antimicrobials; animal antimicrobials; chemical characterization; bacteriocins
(This special issue belongs to the Section Natural Products Chemistry)
Exploring the Therapeutic Potential of Peptides in Anti-Cancer Treatments submission deadline 30 Nov 2025 | 1 articles | Viewed by 1487 | Submission Open
Keywords: anticancer peptides; antimicrobial peptides; cell-penetrating peptides; therapeutic peptides; cancer vaccine; theranostics; peptidomimetics; anticancer drugs; metal– peptide drugs
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Heterocyclic Synthesis, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1341 | Submission Open
Keywords: heterocycles; stereoselective synthesis; sustainable synthesis; one-pot reactions; multicomponent reactions; catalysis
(This special issue belongs to the Section Organic Chemistry)
Functional Materials for Chemical Sensing in Molecules
edited by , and Ming Hou
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1327 | Submission Open
Keywords: functional materials; sensing materials; nanomaterials; composites; design and synthesis; chemical sensing; gas sensors; humidity sensors; biosensors
(This special issue belongs to the Section Materials Chemistry)
Advances in Transition Metal Catalysis for Organic Synthesis
edited by and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1307 | Submission Open
Keywords: transition metal catalysis; organometallic chemistry; organic synthesis; alkene functionalization; C-H functionalization
(This special issue belongs to the Section Organometallic Chemistry)
Advances in Electrochemical Reactions, Mechanisms and Sensing Applications submission deadline 30 Nov 2025 | 1 articles | Viewed by 1279 | Submission Open
Keywords: electrochemical reactions; reaction mechanisms; electrocatalysis; electrochemical sensing; organic and organometallic compounds; analytical electrochemistry
(This special issue belongs to the Section Electrochemistry)
Inorganic Photoelectric Functional Materials: Design, Synthesis and Applications
edited by Luyi Zou
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1218 | Submission Open
Keywords: photoelectric material; molecular structure; molecular composition; structural performance
(This special issue belongs to the Section Inorganic Chemistry)
Opportunities and Challenges in Protein Crystallography
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1160 | Submission Open
Keywords: protein crystals; X-ray diffraction; cryo-EM; small-angle X-ray scattering; phasing methods; structural analysis
(This special issue belongs to the Section Chemical Biology)
Natural-Based Sorbents for Water Remediation submission deadline 30 Nov 2025 | 2 articles | Viewed by 1157 | Submission Open
Keywords: natural sorbents; removal of organic or inorganic contaminants from water; physical and chemical characterization of the sorbent; kinetic and equilibrium sorptive tests; evaluation of thermodynamic and kinetic parameters; determination of the actual sorption mechanism
(This special issue belongs to the Section Physical Chemistry)
Bioactive Compounds Encapsulation System: Design and Applications
edited by and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1142 | Submission Open
Keywords: bioactive compounds; encapsulation; nanocarriers; bioavailability; targeted delivery; drug delivery; functional foods
(This special issue belongs to the Section Food Chemistry)
Food Bioactive Compounds: Chemical Challenges and Opportunities, 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 1142 | Submission Open
Keywords: bioactive compounds; non-conventional extraction techniques; modern analytical methods; authenticity; molecular mechanism; functional properties; antimicrobial; antitumoral; anti-inflammatory; and antioxidant properties
(This special issue belongs to the Section Cross-Field Chemistry)
Nutritional and Bioactive Components of Edible Parts of Medicinal Plants
edited by , and Joanna Milala
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1065 | Submission Open
Keywords: herbs; dietary fiber; polyphenols; ellagitannins; antioxidants; minerals; gastrointestinal track
(This special issue belongs to the Section Food Chemistry)
Advanced Oxidation of Emerging Pollutants in Water
edited by Rongfang Yuan
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1044 | Submission Open
Keywords: advanced oxidation; photocatalytic oxidation; photoelectrocatalytic processes; ultrasonic irradiation; peroxymonosulfate activation; emerging pollutants; water treatment
(This special issue belongs to the Section Green Chemistry)
Novel Membranes and Coatings for Biomedical and Food Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1020 | Submission Open
Keywords: model cell membranes; biocompatible and edible coatings; bioactive compounds; nutrients; biomaterials; surface characteristics; dispersion systems
(This special issue belongs to the Section Applied Chemistry)
Design, Synthesis and Evaluation of Novel Anticancer Agents, 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 1004 | Submission Open
Keywords: anticancer agents; medicinal chemistry; heterocycles; azines; azoles
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Anticancer Activity of Natural Products and Related Compounds
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 912 | Submission Open
Keywords: natural compounds; anticancer activity; bioactive compounds; cancer therapeutics; drug resistance; synergistic effect
(This special issue belongs to the Section Natural Products Chemistry)
Extraction of Plant-Derived Bioactives: Impacts on Human Health and Pharmacological Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 898 | Submission Open
Keywords: plant extracts; bioactivity; pharmacology; human health; natural compounds extraction; natural compounds activity; pharmacokinetics
(This special issue belongs to the Section Natural Products Chemistry)
Nanomaterials for Biomedicine: Innovations and Challenges
edited by and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 867 | Submission Open
Keywords: nanomaterial; targeted drug delivery; bio-imaging; antimicrobial application; cancer immunotherapy; nanovaccine
(This special issue belongs to the Section Nanochemistry)
Applications of EPR Spectroscopy in Various Fields of Scientific Research submission deadline 30 Nov 2025 | 1 articles | Viewed by 857 | Submission Open
Keywords: EPR spectroscopy; free radicals; paramagnetic species; dosimetry; food technology; archeology; environmental; catalysis
(This special issue belongs to the Section Analytical Chemistry)
Natural Bioactive Compounds from Traditional Asian Plants—Second Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 845 | Submission Open
Keywords: natural product; medicinal plants; traditional medicine; bioactive molecules; crude drugs
(This special issue belongs to the Section Natural Products Chemistry)
Physical–Chemical Interactions and Composition–Structure–Property Modifications During Food Processing submission deadline 30 Nov 2025 | 1 articles | Viewed by 751 | Submission Open
Keywords: structure; food; thermal properties; chemical composition
(This special issue belongs to the Section Food Chemistry)
Purposeful Assembly and Versatile Applications of Advanced Crystalline Frameworks
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 664 | Submission Open
Keywords: metal– organic frameworks; covalent organic frameworks; hydrogen-bonded organic frameworks; post-synthetic modification strategy; composite materials
(This special issue belongs to the Section Inorganic Chemistry)
Biopolymers for Drug Delivery Systems
edited by and Petra Arany
submission deadline 30 Nov 2025 | 1 articles | Viewed by 635 | Submission Open
Keywords: drug delivery systems; biopolymers; personalized medication; nanoparticle; hydrogel; 3D printing
(This special issue belongs to the Section Medicinal Chemistry)
A Themed Issue in Honor of the 20th Anniversary of the Mexican Academy of Organic Chemistry (AMQO)
edited by Ivan Romero-Estudillo, , Alicia Boto and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 548 | Submission Open
Keywords: organic chemistry; chemistry process; chemistry; chemical science; science in Mexico
(This special issue belongs to the Section Organic Chemistry)
Bio-Based and Natural Compounds: A Sustainable Approach for an Environmental Transition submission deadline 30 Nov 2025 | 1 articles | Viewed by 502 | Submission Open
Keywords: bio-based materials; green materials; environmental application; natural compounds; characterization; sustainability
(This special issue belongs to the Section Green Chemistry)
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