Immunomodulatory and Anti-Inflammatory Activities of Natural Compounds with Adaptogenic Potential
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 15 June 2026 | Viewed by 1442
Special Issue Editors
Interests: phytochemicals; drug interactions; plant-based immunostimulants; phytochemical analysis
Interests: adaptogens; natural products; anti-inflammatory activity; LC-MS; gut microbiota; oxidative stress; enzyme inhibition; chronic diseases
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to this Special Issue, which aims to explore the immunomodulatory and anti-inflammatory properties of natural compounds, with a particular focus on substances traditionally recognized as adaptogens. Natural compounds have long been used in various traditional medical systems to modulate physiological responses to stress, enhance immune function, and reduce inflammation, all of which are closely inter-related mechanisms.
This Special Issue seeks to bridge the gap between traditional knowledge and modern biomedical research by focusing on phytochemicals, herbal preparations, and bioactive plant metabolites that impact the regulation of the immune system and inflammation-related pathways. We welcome submissions investigating the molecular mechanisms, preclinical and clinical effects, and potential therapeutic applications of such substances in the context of immune-related and inflammatory disorders.
For this Special Issue, we welcome original research articles and reviews in areas of research including (but not limited to) the following:
- Anti-inflammatory pathways of natural compounds;
- Adaptogenic effects and immune homeostasis;
- Herbal immunostimulants in infection or stress response;
- Clinical applications of plant-derived immunomodulators;
- Synergistic or combinatorial effects with pharmaceuticals;
- Systems biology approaches to adaptogen research;
- Chemical analysis and identification of phytochemicals (LC-MS, NMR, TLC).
We look forward to receiving your contributions.
Prof. Dr. Daniel Załuski
Guest Editor
Dr. Jakub Gębalski
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- adaptogens
- immunomodulation
- inflammation
- phytochemicals
- herbal medicine
- cytokines
- oxidative stress
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