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Biological Evaluation of Plant Extracts

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 31 December 2025

Special Issue Editor


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Guest Editor

Special Issue Information

Dear Colleagues,

I am delighted to be the Guest Editor and part of the team for this Special Issue of Molecules. We hope to offer our readers high-quality, cutting-edge research in the fields of phytochemistry, phytopharmacology and molecular biology. The biological evaluation of plant extracts is a critical step in the discovery and development of novel therapeutic agents derived from natural sources. Medicinal plants have been traditionally used for centuries in the treatment of various diseases, and modern scientific approaches aim to validate and expand this knowledge through rigorous experimental methods. Biological evaluation involves a wide range of in vitro and in vivo assays designed to assess pharmacological activities, such as antimicrobial, anti-inflammatory, antioxidant, cytotoxic, and immunomodulatory effects. These studies also encompass toxicity screening to ensure safety and identify potential side effects. The efficacy of plant extracts is largely influenced by their phytochemical composition, which includes alkaloids, flavonoids, terpenoids, phenolic compounds, and other bioactive constituents. The standardization of extract preparation, accurate quantification of active compounds, and reproducible testing models are essential for generating reliable data. Moreover, the integration of advanced techniques, such as high-throughput screening, metabolomics, proteomics, and molecular docking, further enhances our understanding of phytochemicals’ mechanisms of action. The biological evaluation of plant extracts not only supports their traditional uses but also contributes to the development of evidence-based phytotherapeutics and the identification of lead compounds for pharmaceutical development.

Dr. Rumyana Simeonova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medicinal plants
  • phytochemistry
  • phytopharmacology
  • metabolomics
  • proteomics
  • cell signalization

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Published Papers

This special issue is now open for submission.
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