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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into the Diagnosis, Management, and Interventions of Mood Disorders

edited by Ioana Valentina Micluţia and

Cristian Delcea

submission deadline 25 Nov 2025 | 4 articles | Viewed by 8795 | Submission Open

Keywords: mood disorders; anxiety; depression; psychotherapy; pharmacological treatments; cognitive behavioral therapy; dialectical behavioral therapy; emotional dysregulation

(This special issue belongs to the Section Psychiatry)

Diagnostic Imaging in the Theranostic Era: From ¹³¹I Scintigraphy to the Latest Innovations

edited by Francesco Bertagna and

Pietro Bellini

submission deadline 25 Nov 2025 | 1 articles | Viewed by 1028 | Submission Open

Keywords: theranostic; nuclear medicine therapy; thyroid cancer; DTC; neuroendocrine tumor; PET; PRRT; prostate cancer; radiotracers; dosimetry; narrative review; systematic review; comprehensive review; radioiodine

(This special issue belongs to the Section Oncology)

Thermology Health Care Applications and Medical Thermography

edited by

Marcos Leal Brioschi

submission deadline 30 Nov 2025 | 1 articles | Viewed by 14736 | Submission Open

Keywords: public health; medical termography; pain; breast cancer; cardiovascular disease; surgery; artificial intelligence; HealthTech; diabetes

Updates on Risk Factors, Prevention and Treatment of Knee Disease

edited by

Giuseppe Solarino

Giuseppe Maccagnano

and

Michele Coviello

submission deadline 30 Nov 2025 | 3 articles | Viewed by 7982 | Submission Open

Keywords: sports medicine; trauma; degenerative; regenerative; rehabilitation; prevention

(This special issue belongs to the Section Orthopedics)

Stroke: Diagnostic Approaches and Therapies: 2nd Edition

edited by

Anna Podlasek

and Iris Quasar Grunwald

submission deadline 30 Nov 2025 | 3 articles | Viewed by 5779 | Submission Open

Keywords: stroke; thrombolysis; tenecteplase; mechanical thrombectomy; neuroprotection; neuroimaging

(This special issue belongs to the Section Neurology)

Clinical Advances in Gynecological Surgery

edited by

Vito Andrea Capozzi

submission deadline 30 Nov 2025 | 3 articles | Viewed by 5727 | Submission Open

Keywords: gynecology; oncology; surgery

(This special issue belongs to the Section Obstetrics and Gynecology)

Quality of Life Assessment in Oncology Patients

edited by

Raluca Maria Pop

and Claudia Florentina Militaru

submission deadline 30 Nov 2025 | 3 articles | Viewed by 5030 | Submission Open

Keywords: quality of life; oncology patients; individual needs; clinical decisions

(This special issue belongs to the Section Oncology)

Primary Care in the Post-Pandemic Era

edited by Leonas Valius and Gediminas Urbonas

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3318 | Submission Open

Keywords: prevention in primary care; multimorbidity; cardiovascular endpoints; primary care team; immunization; appropriate usage of antibiotics; post-COVID period

(This special issue belongs to the Section Epidemiology & Public Health)

Development and Application of Objective Measures in Physiotherapy for Musculoskeletal Disorders, Orthopedics, and Sports Medicine—2nd Edition

edited by

Aleksandra Królikowska

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3056 | Submission Open

Keywords: clinical evaluation; functional performance; injury prevention; muscle strength; orthopedics; performance-based measures; physical examination; physiotherapy; rehabilitation; reliability; sports medicine; surface electromyography; validity

(This special issue belongs to the Section Orthopedics)

Contemporary Trends in Urothelial Cancer Management

edited by Panagiotis Mourmouris and Nikolaos Kostakopoulos

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2980 | Submission Open

Keywords: bladder cancer; upper-tract urinary carcinoma; radical cystectomy; radical nephroureterectomy; immunotherapy; metastatic urothelial carcinoma; robotic surgery

(This special issue belongs to the Section Urology & Nephrology)

High-Grade Gliomas: Updates and Challenges

edited by

Sandra Leisz

and

Maximilian Scheer

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2417 | Submission Open

Keywords: glioma; glioblastoma; neuro-oncology; tumour biology; imaging; radiotherapy; chemotherapy

(This special issue belongs to the Section Oncology)

Refractive Surgery and Cataract Surgery: Updates and Challenges

edited by

Ferdinando Cione

and

Nicola Rosa

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1892 | Submission Open

Keywords: refractive surgery; cataract and refractive surgery; IOL power calculation after refractive surgery; biometry

(This special issue belongs to the Section Ophthalmology)

Aortic Stenosis: Diagnosis and Clinical Management

edited by Tsung‐Ying Tsai and

Ali Aldujeli

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1601 | Submission Open

Keywords: aortic stenosis; echocardiography; transcatheter aortic valve replacement (TAVR); surgical aortic valve replacement (SAVR); hemodynamics; valvular heart disease; cardiovascular imaging; guideline-directed therapy; prognosis; multidisciplinary care

(This special issue belongs to the Section Cardiology)

Erectile Dysfunction and Sexual Health: Current Trends in Evaluation and Treatment

edited by Bogdan Petrut, Bogdan Ovidiu Feciche, Nicolae Crisan and

Daniel Porav-Hodade

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1534 | Submission Open

Keywords: erectile dysfunction; ejaculatory and orgasmic disorders; vascular; neurogenic; endocrinologic; iatrogenic; psychogenic

(This special issue belongs to the Section Urology & Nephrology)

Gynecological and Oncological Diseases in the Aged

edited by Stefan Sajdak, Katarzyna Plagens-Rotman and Monika Englert-Golon

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1186 | Submission Open

Keywords: gynecology; oncology; old age; women

(This special issue belongs to the Section Obstetrics and Gynecology)

Innovations in Pelvic Organ Prolapse Management: From Diagnosis to Recovery

edited by

Themos Grigoriadis

, Dimitrios Zacharakis and

Athanasios Douligeris

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1137 | Submission Open

Keywords: urogynecology; pelvic organ prolapse; reconstructive pelvic surgery; vaginal surgery; urinary incontinence; pelvic floor dysfunction; urodynamcs

(This special issue belongs to the Section Obstetrics and Gynecology)

Uveitis: From Basic Research to Clinical Practice

edited by Giovanni Alessio and

Valeria Albano

submission deadline 30 Nov 2025 | Viewed by 635 | Submission Open

Keywords: uveitis; posterior uveitis; anterior uveitis; vitritis; masquerade syndrome

(This special issue belongs to the Section Ophthalmology)

Acute Respiratory Distress Syndrome and Lung Injury: From Diagnosis to Treatment

edited by

Thomas Schaible

submission deadline 30 Nov 2025 | Viewed by 599 | Submission Open

Keywords: Acute Respiratory Distress Syndrome; lung injury; ECMO; pulmonary hypertension; diaphragmatic hernia; diagnostic precision; early treatment

(This special issue belongs to the Section Pulmonology)

New Trends and Advances in Head and Neck Oncology

edited by Federica Ruggiero and Giovanni Badiali

submission deadline 30 Nov 2025 | 1 articles | Viewed by 526 | Submission Open

Keywords: head and neck surgery; robotic-assisted surgery; reconstruction

(This special issue belongs to the Section Surgery)

Clinical and Basic Research on Pediatric Chronic Rhinosinusitis

edited by

Antonio Mario Bulfamante

and

Alberto Maria Saibene

submission deadline 30 Nov 2025 | Viewed by 523 | Submission Open

Keywords: rhinosinusitis; pediatric; quality of life; nasal microbiome; allergy; biologics; endoscopic sinus surgery; inflammation; asthma

(This special issue belongs to the Section Pediatrics)

Research on Anesthesiology in Laparoscopic Surgery

edited by

Valentin Titus Grigorean

Mircea Lițescu

and Daniela Godoroja

submission deadline 30 Nov 2025 | Viewed by 518 | Submission Open

Keywords: general anesthesia (GA); laparoscopy; robotic surgery; pneumoperitoneum; ventilation; position; multimodal analgesia; postoperative care

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Neurosurgery for Brain or Spine Tumors: Recent Technical Advances

edited by Bartosz Sokół and Ondra Petr

submission deadline 30 Nov 2025 | 1 articles | Viewed by 433 | Submission Open

Keywords: neurosurgery; brain tumors; spine tumors; minimally invasive surgery; robot-assisted surgery; neuro-navigation; intraoperative imaging; precision medicine; molecular profiling; immunotherapy

(This special issue belongs to the Section Neurology)

Research on Burn Care and Reconstructive Surgery

edited by

Tiberiu Paul Neagu

submission deadline 30 Nov 2025 | Viewed by 188 | Submission Open

Keywords: burn injury; burn eschar; burn care; surgical excision of burns; enzymatic debridement; skin graft; reconstructive surgery; burn sequelae; burn scar

(This special issue belongs to the Section Surgery)

Cancer Metabolism: Current Understanding and Therapies

edited by

Kaili Liu

and Jiangnan Hu

submission deadline 30 Nov 2025 | Viewed by 188 | Submission Open

Keywords: cancer metabolism; metabolic reprogramming; tumor microenvironment; metabolic targeted therapies; diagnostics and biomarkers; immunometabolism; drug development; precision medicine

(This special issue belongs to the Section Oncology)

New Progress in Kidney Transplantation and Surgery

edited by

Hans-Michael Hau

submission deadline 30 Nov 2025 | Viewed by 182 | Submission Open

Keywords: renal transplantation; pancreas transplantation; robotic surgery; living donor renal transplantation; transplant outcome; immunosuppression; transplantation surgery rejection; organ procurement; tolerance induction; extended criteria; machine perfusion; tolerance; biomarkers; organ engineering; non-heart-beating donors; renal pumps; artificial intelligence; machine learning; translational research; personalized medicine

(This special issue belongs to the Section Urology & Nephrology)

Laparoscopic Surgery: Purpose, Procedure, and Benefits

edited by Claudia Rudroff and

Sebastian Ludwig

submission deadline 30 Nov 2025 | Viewed by 119 | Submission Open

Keywords: minimal-invasive surgical techniques; innovative techniques; innovative concepts; pelvic organ prolapse; defecation disorder

(This special issue belongs to the Section Surgery)

Advances in Acute Myocardial Infarction

edited by Šime Manola and Ivana Jurin

submission deadline 10 Dec 2025 | 4 articles | Viewed by 13154 | Submission Open

Keywords: percutaneous coronary intervention; heart failure; lipid-lowering therapy; SGLT2 inhibitors; multivessel disease; beta blockers; prasugrel; ticagrelor; semaglutide

(This special issue belongs to the Section Cardiology)

New Developments in Plastic Surgery

edited by

Bryan Lim

Ishith Seth

and

Warren Matthew Rozen

submission deadline 15 Dec 2025 | 3 articles | Viewed by 8402 | Submission Open

Keywords: hand surgery; microsurgery; breast reconstruction; artificial intelligence; rhinoplasty; blepharoplasty; aesthetic surgery; surgical anatomy; 3D printing

(This special issue belongs to the Section Surgery)

New Strategies for the Diagnosis and Treatment of Rheumatic and Musculoskeletal Diseases

edited by Elena Amaricai and

Carmen Delia Nistor-Cseppento

submission deadline 15 Dec 2025 | 4 articles | Viewed by 6519 | Submission Open

Keywords: osteoarthritis; inflammatory rheumatic diseases; osteoporosis; low back pain; physical medicine; rehabilitation; disability; quality of life

(This special issue belongs to the Section Hematology and Immunology)

Advances in the Diagnosis and Treatment of Coronary Artery and Peripheral Artery Diseases

edited by

Ovidiu Mitu

and

Alexandru Dan Costache

submission deadline 15 Dec 2025 | 3 articles | Viewed by 4072 | Submission Open

Keywords: peripheral artery disease; coronary artery disease; cardiac rehabilitation; cardiovascular prevention; revascularisation; percutaneous coronary intervention; coronary artery bypass graft

(This special issue belongs to the Section Cardiology)

Gallbladder, Bile Duct and Pancreas Disorders: Current Challenges, New Perspectives and Innovative Techniques

edited by

Daniel Paramythiotis

Robert Grützmann

, Vasileios Papaziogas, Dimitrios Raptis and

Eleni Karlafti

submission deadline 20 Dec 2025 | 7 articles | Viewed by 28126 | Submission Open

Keywords: pancreas; biliary tract; pancreatobiliary diseases; pancreas neoplasm; tumor; ERCP; EUS; management; therapy; technique; surgery

(This special issue belongs to the Section Gastroenterology & Hepatology)

Precision Medicine Approach in Septic Patients

edited by

Gabriela Droc

and

Sebastian Isac

submission deadline 20 Dec 2025 | 1 articles | Viewed by 4810 | Submission Open

Keywords: sepsis; septic shock; precision medicine; epigenomics; cytomics; genomics; proteomics; metabolomics; transcriptomics

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advances in Bypass Surgery in Cardiology

edited by

Giuseppe Nasso

and

Ignazio Condello

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4618 | Submission Open

Keywords: Coronary Artery Bypass Grafting (CABG); minimally invasive cardiac surgery; cardiopulmonary bypass; hybrid coronary revascularization; off-pump surgery; myocardial protection; surgical outcomes in cardiology

(This special issue belongs to the Section Cardiology)

Current Advances in Diagnosis and Surgical Treatment of the Head and Neck Disorders, 2nd Edition

edited by Poramate Pitak-Arnnop and

Christian Stoll

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3286 | Submission Open

Keywords: head and neck injury; head and neck trauma; head and neck cancer; oncology; head and neck infection; congenital orofacial deformity; orofacial pain; facial plastic and reconstructive surgery; facial aesthetic medicine; head and neck reconstruction

(This special issue belongs to the Section Surgery)

Advances in Cervical Cancer Treatment and HPV Management: From Conventional Therapies to Emerging Strategies

edited by Mariano Catello Di Donna and Maria Cristina Solazzo

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3008 | Submission Open

Keywords: cervical cancer; HPV; immunotherapy; targeted therapies; personalized medicine; radical hysterectomy; fertility-sparing surgery; multimodal treatment

(This special issue belongs to the Section Obstetrics and Gynecology)

Diagnosis and Treatment of Obstructive Sleep Apnea

edited by Goran Račić, Željka Roje and Zlatko Kljajic

submission deadline 20 Dec 2025 | Viewed by 159 | Submission Open

Keywords: obstructive sleep apnea; polysomnography; obstructive sleep apnea diagnosis; obstructive sleep apnea treatment; obstructive sleep apnea etiology; obstructive sleep apnea complications; adult OSA; pediatric OSA

(This special issue belongs to the Section Pulmonology)

End-Stage Kidney Disease (ESKD)

edited by Ruta Vaiciuniene,

Inga Arune Bumblyte

and Asta Stankuviene

submission deadline 22 Dec 2025 | 5 articles | Viewed by 4408 | Submission Open

Keywords: kidney transplantation; hemodialysis; peritoneal dialysis; survival; management; quality of life

(This special issue belongs to the Section Urology & Nephrology)

Diagnosis and Treatment of Cervical Cancer: Second Edition

edited by

Tullio Golia D’Augè

and Giorgia Perniola

submission deadline 25 Dec 2025 | 1 articles | Viewed by 1352 | Submission Open

Keywords: cervical cancer; radical hysterectomy; prevention; cervical intraepithelial neoplasia; cervical cancer screening; early diagnosis

(This special issue belongs to the Section Obstetrics and Gynecology)

Update on B-Cell Leukemias and Lymphomas

edited by

Diana Cenariu

and

Adrian-Bogdan Țigu

submission deadline 25 Dec 2025 | 1 articles | Viewed by 1166 | Submission Open

Keywords: biomarkers for diagnosis; genetic mutations; epigenetic regulation; niche interaction; immunotherapy; targeted therapy; CAR T-cell therapy

(This special issue belongs to the Section Hematology and Immunology)

Inflammatory Bowel Disease (IBD): Pathogenesis, Clinical Management, and Emerging Therapies

edited by Dana Crisan and

Vlad Dumitru Brata

submission deadline 25 Dec 2025 | Viewed by 269 | Submission Open

Keywords: inflammatory bowel disease; pathogenesis; disease management; emerging therapies

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advances in the Diagnosis and Treatment of Type 2 Diabetes Mellitus

edited by

Bogdan Timar

, Romulus Timar and

Adina Braha

submission deadline 30 Dec 2025 | 5 articles | Viewed by 11977 | Submission Open

Keywords: novel diagnostic markers of type 2 diabetes and its complications; continuous glucose monitoring in type 2 diabetes; time in tight range in type 2 diabetes; nanotechnology in type 2 diabetes; SGLT-2 inhibitors; GLP-1 receptor agonists; dual GIP/GLP-1 receptor agonists; next-generation GLP-1/GIP/glucagon triple agonists; amylin analogues; bariatric surgery in managing type 2 diabetes and obesity; gut microbiota in type 2 diabetes; liposome; monoclonal antibodies; Lp a; MASH in type 2 diabetes; differentiated thyroid cancer and pancreatic cancer in type 2 diabetes mellitus

(This special issue belongs to the Section Endocrinology)

Recent Advances in Gynecological Surgery

edited by

Felice Sorrentino

submission deadline 30 Dec 2025 | 4 articles | Viewed by 5578 | Submission Open

Keywords: hysteroscopy; laparoscopy; robotics; vNOTES; laser; gynecological surgery; resectoscope

(This special issue belongs to the Section Obstetrics and Gynecology)

Psychiatric Comorbidities and Substance Use Among Individuals with Physical Health Issues and Chronic Diseases

edited by

Jagdish Khubchandani

submission deadline 30 Dec 2025 | Viewed by 210 | Submission Open

Keywords: psychiatry; substance use; chronic disease; physical health issues; addiction; mental health; health outcomes; alcohol; tobacco; and other drug use; healthcare utilization

Advances in Soft and Hard Tissue Management Around Dental Implants

edited by

Roberto Rossi

and

Fabrizio Bambini

submission deadline 31 Dec 2025 | 10 articles | Viewed by 24003 | Submission Open

Keywords: dental implants; soft tissue around implants; bone regeneration; prosthetic implants; esthetic implants

(This special issue belongs to the Section Dentistry and Oral Health)

Clinical Applications of Modern Technologies in Neurosurgery and Spine Surgery

edited by

Mirza Pojskić

Christopher Nimsky

and

Miriam H. A. Bopp

submission deadline 31 Dec 2025 | 8 articles | Viewed by 23359 | Submission Open

Keywords: modern technologies; neuronavigation; augmented reality; virtual reality; robotics; endoscopy; tumor treating fields; tumor biology; intraoperative ultrasound; intraoperative computed tomography; intraoperative magnetic resonance imaging; neuroradiology; neurosurgery; spine surgery

(This special issue belongs to the Section Neurology)

Chronic Inflammatory Skin Diseases: Where We Are and Where We Are Going: 2nd Edition

edited by

Fabrizio Martora

and

Matteo Megna

submission deadline 31 Dec 2025 | 6 articles | Viewed by 14678 | Submission Open

Keywords: psoriasis; atopic dermatitis; hidradenitis suppurativa; skin inflammatory disease

(This special issue belongs to the Section Dermatology)

Physical Therapy: A New Perspective

edited by

Manuel González-Sánchez

and Laura Zlibinaite

submission deadline 31 Dec 2025 | 6 articles | Viewed by 14480 | Submission Open

Keywords: physical therapy; physiotherapy; therapeutic exercise; rehabilitation; exercise prescription; treatment techniques; musculoskeletal health; movement impairments; functional abilities; innovation

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Early Diagnosis and Management of Glioma

edited by Maurizio Iacoangeli and

Denis Aiudi

submission deadline 31 Dec 2025 | 4 articles | Viewed by 8178 | Submission Open

Keywords: glioma; glioblastoma; neuroimaging; neuro-oncology; early diagnosis; modern technologies; neurosurgery; tumor biology; early therapy; new therapies

(This special issue belongs to the Section Oncology)

New Insights into Plastic and Reconstructive Surgery

edited by

Francesco De Francesco

and Michele Riccio

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7219 | Submission Open

Keywords: microsurgery; regenerative medicine; tissue engineering; robotic surgery; biomimetic materials; aesthetic surgery; wound healing; 3D printing; reconstructive techniques; psychological impacts

(This special issue belongs to the Section Surgery)

Diabetes and Obesity: What Is New in 2025

edited by

Manfredi Rizzo

and

Ali Abbas Rizvi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 6497 | Submission Open

Keywords: diabetes; obesity; metabolic syndrome; cardiovascular disease; insulin resistance

(This special issue belongs to the Section Endocrinology)

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