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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Modern Diagnostics and Therapy for Vitreoretinal Diseases

edited by

Miguel Antonio Busquets

and

Anat Lowenstein

submission deadline 10 Oct 2025 | 1 articles | Viewed by 1982 | Submission Open

Keywords: retinal pharmacotherapy; artificial intelligence; image recognition; optical coherence tomography; remote retinal monitoring; exudative retinal disease; geographic atrophy

(This special issue belongs to the Section Ophthalmology)

Clinical Updates and Future Perspectives on the Chronic Pain Management

edited by

Sergio Hernández Sánchez

and

Jasemin Todri

submission deadline 15 Oct 2025 | 1 articles | Viewed by 1552 | Submission Open

Keywords: chronic pain management; pain assessment; regenerative medicine in pain management; multidisciplinary pain treatment; wearable technology in pain monitoring; personalized pain therapy

(This special issue belongs to the Section Neurology)

Revolutionizing Cardiopulmonary Resuscitation: Contemporary Advances and Challenges

edited by Georgios Mavrovounis,

Ioannis Pantazopoulos

and

Maria Mermiri

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4806 | Submission Open

Keywords: cardiopulmonary resuscitation; defibrillation; mechanical CPR; emergency medicine; automated external defibrillator; e-CPR; post-resuscitation period; neurological outcomes

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Gut Microbiota and Gastrointestinal Cancer: Pathways to Progression and Opportunities for Intervention

edited by Vikas Kumar Somani,

Naoshad Muhammad

and

Somya Aggarwal

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2453 | Submission Open

Keywords: gut microbiota; gastrointestinal cancer; dysbiosis; colorectal cancer; gastric cancer; pancreatic cancer; esophageal cancer; cancer progression; tumor microenvironment; inflammation; immune modulation; metabolic alterations; probiotics; prebiotics; microbial therapies; fecal microbiota transplantation; cancer immunotherapy; tumor-associated microbiome; gut– brain axis; microbiome modulation

(This special issue belongs to the Section Oncology)

Advances in Pathogenesis, Rehabilitation, and Treatment of Knee Osteoarthritis

edited by

László Irsay

and Magdalena-Rodica Trăistaru

submission deadline 25 Oct 2025 | 1 articles | Viewed by 2240 | Submission Open

Keywords: pathogenesis; evidence based KOA; rehabilitation KOA; treatment KOA; surgery KOA

(This special issue belongs to the Section Orthopedics)

Pulmonary Fibrosis: Current Understanding and Future Directions

edited by Satoshi Okamori and

Yusuke Nakamura

submission deadline 25 Oct 2025 | 1 articles | Viewed by 966 | Submission Open

Keywords: pulmonary fibrosis; interstitial lung disease (ILD); idiopathic pulmonary fibrosis (IPF); hypersensitivity pneumonitis; bronchoscopy; cryobiopsy; fibrotic lung disease; acute exacerbations; pleuroparenchymal fibroelastosis; rehabilitation; nutrition

(This special issue belongs to the Section Pulmonology)

Development and Application of Digestive Endoscopy

edited by

Giacomo Emanuele Maria Rizzo

, Sara Nikolic and

Lucía Guilabert

submission deadline 25 Oct 2025 | 1 articles | Viewed by 861 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; interventional endoscopy; robotic endoscopy; gastroenterology; advanced imaging

(This special issue belongs to the Section Gastroenterology & Hepatology)

Epidemiology of Geriatric Syndromes: Life Course Risk or Protective Factors

edited by Carlos Alfonso Reyes-Ortiz

submission deadline 25 Oct 2025 | Viewed by 521 | Submission Open

Keywords: older adults; geriatric syndromes; chronic disease; early life adversity; adverse childhood experiences; risk factors; protective factors

Multimodal Imaging Techniques in Myocardial Ischemia: Current Applications and Future Prospects

edited by Fausto Pizzino and Giovanni Concistrè

submission deadline 30 Oct 2025 | 3 articles | Viewed by 7649 | Submission Open

Keywords: myocardial ischemia; cardiac magnetic resonance; coronary computed tomography angiography; intravascular imaging; myocardial infarction with non-obstructive coronary arteries; ischemia with non-obstructive coronary arteries; coronary artery disease

(This special issue belongs to the Section Cardiology)

Advances and Perspectives in Esophageal Cancer Treatment

edited by Koji Otsuka and

Florin Achim

submission deadline 30 Oct 2025 | Viewed by 2698 | Submission Open

Keywords: minimally invasive esophagectomy; robotic esophagectomy; locally advanced esophageal cancer; immunotherapy for esophageal cancer; cervical esophageal cancer; multidisciplinary approach to esophageal cancer

(This special issue belongs to the Section Surgery)

The Challenges and Prospects in Clinical Cardiology and Angiology

edited by Vincenzo Zaccone and

Giulio Francesco Romiti

submission deadline 31 Oct 2025 | 6 articles | Viewed by 19135 | Submission Open

Keywords: cardiology; angiology; cardiovascular diseases; vascular health; diagnostic techniques; treatment strategies; translational research

(This special issue belongs to the Section Cardiology)

Current Advancements in Menopause Treatment and Management

edited by Richa Sood

submission deadline 31 Oct 2025 | 3 articles | Viewed by 11707 | Submission Open

Keywords: menopause; vasomotor symptoms; hormone therapy; tele-medicine; drug innovation; machine learning; artificial intelligence; cardiovascular; osteoporosis

(This special issue belongs to the Section Obstetrics and Gynecology)

Future Trends in Breast Cancer Management

edited by

Dinesh K. Thekkinkattil

submission deadline 31 Oct 2025 | 5 articles | Viewed by 11250 | Submission Open

Keywords: breast cancer; breast reconstruction; artificial intelligence; machine learning; staging; treatment; targeted therapy; digital pathology; radiomics; oncoplastic surgery; prognosis; immunotherapy; liquid biopsy

(This special issue belongs to the Section Oncology)

Innovations in Amputation Care

edited by

Gerhard M. Hobusch

and

Jennifer Ernst

submission deadline 31 Oct 2025 | 4 articles | Viewed by 10281 | Submission Open

Keywords: bone-anchored prosthesis; targeted muscle reinnervation; amputation medicine; targeted sensory reinnervation; artificial intelligence; motor imagery; digital transformation; patient-reported outcome measurement

(This special issue belongs to the Section Orthopedics)

Addressing the Changes and Innovations in the Treatment of Gynecological Cancers

edited by

Federico Ferrari

submission deadline 31 Oct 2025 | 3 articles | Viewed by 9361 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; minimally invasive surgery; adjuvant treatment; targeted therapy; immunotherapy; endoscopy

(This special issue belongs to the Section Oncology)

Advanced Technologies in Pediatric Nephrology

edited by Kiran K. Upadhyay

submission deadline 31 Oct 2025 | 3 articles | Viewed by 7770 | Submission Open

Keywords: pediatrics; kidney transplantation; dialysis; hypertension; nephrotic syndrome; glomerulonephritis; lupus nephritis; chronic kidney disease; voiding dysfunction; renal tubular disease

(This special issue belongs to the Section Pediatrics)

Gastric Sleeve Surgery: Techniques, Outcomes, and Future Directions

edited by Anna Maria Różańska-Walędziak and

Maciej Walędziak

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5388 | Submission Open

Keywords: laparoscopic sleeve gastrectomy; bariatric surgery; obesity

(This special issue belongs to the Section Surgery)

Diagnosis and Treatment of Valvular Heart Diseases

edited by

Valentina Grazioli

and Ilaria Franzese

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4773 | Submission Open

Keywords: valvular heart disease; aortic valve disease; mitral valve disease; tricuspid valve disease; pulmonary valve disease; transcatheter intervention; surgery

(This special issue belongs to the Section Cardiology)

Current Management and Future Challenges of Severe Traumatic Brain Injury

edited by Nasim Ahmed

submission deadline 31 Oct 2025 | 1 articles | Viewed by 4578 | Submission Open

Keywords: severe traumatic brain injury; computed tomography; magnetic resonance imaging; decompressive craniectomy; neurosurgical; trauma surgery; Surgical critical care; acute care surgery

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Progress in Venous Thromboembolism Research

edited by Mihaela Hostiuc

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3404 | Submission Open

Keywords: venous thromboembolism; cardiovascular disease; post-thrombotic syndrome; chronic thromboembolic pulmonary disease; prevention

Transcatheter Therapies for Valvular Heart Disease

edited by

Massimo Baudo

and Basel Ramlawi

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2931 | Submission Open

Keywords: aortic valve transcatheter interventions; mitral valve transcatheter interventions; tricuspid valve transcatheter interventions; pulmonary valve transcatheter interventions; transcatheter aortic valve intervention/replacement; mitral transcatheter edge-to-edge repair; transcatheter mitral valve replacement; percutaneous annuloplasty; tricuspid transcatheter edge-to-edge repair; transcatheter pulmonary valve replacement

(This special issue belongs to the Section Cardiology)

Advances in Head and Neck Cancer Management

edited by

Primož Strojan

and

Domen Vozel

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2213 | Submission Open

Keywords: head and neck cancer; targeted therapies; Immunotherapy; imaging techniques; skull-base cancer; radiation therapy

(This special issue belongs to the Section Oncology)

Techniques, Risks and Recovery of Hip Surgery

edited by

Alberto D. Delgado-Martínez

Eduardo García-Rey

and Enrique Guerado

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1688 | Submission Open

Keywords: hip surgery; hip fracture; hip arthroplasty; hip arthroscopy

(This special issue belongs to the Section Orthopedics)

Multiple Sclerosis and Related Disorders: Theory, Methods and Applications

edited by Maura Pugliatti and

Caterina Ferri

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1408 | Submission Open

Keywords: multiple sclerosis; biomarkers; neurodegeneration; neuroimaging; disease-modifying treatments; artificial intelligence; telemedicine; digital therapeutics; personalized medicine

(This special issue belongs to the Section Neurology)

Clinical Updates and Future Perspectives on Acute Myocardial Infarction

edited by Ciro Mauro, Fulvio Cacciapuoti and Gerardo Carpinella

submission deadline 31 Oct 2025 | 1 articles | Viewed by 874 | Submission Open

Keywords: acute myocardial infarction; early-phase management; long-term cardiac care; mechanical circulatory support; intensive care; lipid-lowering and cardioprotective therapies; precision medicine and artificial intelligence in cardiology

(This special issue belongs to the Section Cardiology)

Advances and Challenges in Prehospital Emergency Care

edited by Hayley L. Letson

submission deadline 31 Oct 2025 | 1 articles | Viewed by 811 | Submission Open

Keywords: prehospital; trauma; injury; traumatic brain injury; burns; cardiac arrest; stroke; rural/remote; emergency; resuscitation

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advances and Future Perspectives in Abdominal and Gastrointestinal Surgery

edited by Stamatis Angelopoulos, Efstathios Kotidis and

Elissavet Anestiadou

submission deadline 31 Oct 2025 | 1 articles | Viewed by 807 | Submission Open

Keywords: abdominal surgery; gastrointestinal surgery; general surgery; minimally invasive surgery; perioperative management; surgical innovation

(This special issue belongs to the Section Gastroenterology & Hepatology)

Clinical Application of State-of-the-Art Robotic Surgery

edited by

Jin Wook Yi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 708 | Submission Open

Keywords: surgery for thyroid; parathyroid; and adrenal glands; endoscopic and robotic surgery; basic research of thyroid; parathyroid; and adrenal glands

(This special issue belongs to the Section Surgery)

Impact of Endothelial Dysfunction on Cardiovascular and Pulmonary Diseases

edited by Yuri Matusov and Suhail Dohad

submission deadline 31 Oct 2025 | Viewed by 396 | Submission Open

Keywords: thromboembolic disease; pulmonary hypertension; peripheral arterial disease; coronary artery disease; pulmonary embolism; venous insufficiency

(This special issue belongs to the Section Cardiology)

The Role of Multimodality Imaging in Valve Diseases

edited by Maria Lo Monaco

submission deadline 31 Oct 2025 | Viewed by 204 | Submission Open

Keywords: valve diseases; echocardiography; machine learning; cardiac magnetic resonance; computed tomography; SPECT; PET

(This special issue belongs to the Section Cardiology)

Updates on the Changing Landscape of Immunotherapy and Targeted Therapy in Cancer

edited by

Monica Neagu

and

Gheorghita Isvoranu

submission deadline 31 Oct 2025 | Viewed by 192 | Submission Open

Keywords: cancer immunotherapy; cancer targeted therapy; immune checkpoint targeted therapy; cell therapy in cancer; signal transduction inhibitors; small molecules of cancer drugs; tumor microenvironment; efficacy biomarkers for cancer therapy; mechanisms of resistance

(This special issue belongs to the Section Oncology)

Clinical Advances in Gastrointestinal Surgery

edited by

Valentin Calu

submission deadline 31 Oct 2025 | Viewed by 186 | Submission Open

Keywords: digestive tract cancer; surgical techniques; oncological outcomes; minimally invasive surgery; gastrointestinal oncology

(This special issue belongs to the Section Gastroenterology & Hepatology)

Pharmacological Modulation of NRF2

edited by

Ramón Rodrigo

Luciano Saso

and

Pelin Telkoparan Akillilar

submission deadline 31 Oct 2025 | Viewed by 131 | Submission Open

Keywords: NRF2; redox pharmacology; cancer; inflammatory diseases; neurodegenerative diseases; cardiovascular diseases

(This special issue belongs to the Section Pharmacology)

Ventricular Arrhythmias: Current Advances and Future Perspectives

edited by Zefferino Palamà,

Antonio Scarà

and Antonio Gianluca Robles

submission deadline 31 Oct 2025 | Viewed by 126 | Submission Open

Keywords: sudden death; cardiomyopathies; catheter ablation; cardiac mapping; cardiac imaging

(This special issue belongs to the Section Cardiology)

Recent Advances in Orthodontics and Dental Medicine

edited by Mariana Pacurar and

Dana Gabriela Festila

submission deadline 10 Nov 2025 | 5 articles | Viewed by 8626 | Submission Open

Keywords: artificial intelligence; digital planning; individualization; surgery first; oral medical devices; imagistics; TMJ disorder treatment

(This special issue belongs to the Section Dentistry and Oral Health)

Recent Advances in Plastic and Reconstructive Surgery

edited by Silviu Marinescu and Marius Eugen Ciurea

submission deadline 10 Nov 2025 | 4 articles | Viewed by 6282 | Submission Open

Keywords: minimally invasive procedures; regenerative medicine; non-surgical treatments; artificial intelligence; reconstructive surgery; cosmetic surgery innovations; patient safety

(This special issue belongs to the Section Surgery)

New Insights into Gynecological Disease

edited by

Gaspare Cucinella

and Valentina Billone

submission deadline 15 Nov 2025 | 3 articles | Viewed by 2984 | Submission Open

Keywords: gynecological disease; endometriosis; gynecological cancer; nutraceutical supplementation; infertility; minimally invasive surgery; fertility preservation; psychological implications in gynecological malignancies; ethical and medico-legal implications; PCOS

(This special issue belongs to the Section Obstetrics and Gynecology)

Advances in Interstitial Lung Diseases: From Diagnosis to Treatment

edited by

Jacobo Sellarés

and

Jaume Bordas-Martinez

submission deadline 15 Nov 2025 | 1 articles | Viewed by 973 | Submission Open

Keywords: interstitial lung diseases (ILD); pulmonary fibrosis; early diagnosis; biomarkers; antifibrotic therapy; immunomodulation; precision medicine; telemedicine; holistic care; patient-centered care

(This special issue belongs to the Section Pulmonology)

Diagnosis, Evaluation, and Management of Diseases During Pregnancy: Third Edition

edited by

Marius L. Craina

and

Elena Bernad

submission deadline 20 Nov 2025 | 3 articles | Viewed by 2678 | Submission Open

Keywords: pregnancy; fetus prenatal care; high risk; pathology; genetics; endocrine system diseases; nutrition disorders; cardiovascular diseases; female urogenital diseases; immune system diseases; infections; neoplasms

(This special issue belongs to the Section Obstetrics and Gynecology)

Rheumatoid Arthritis: Advances in Diagnosis, Treatment and Prognosis in Clinical Medicine

edited by Marko Barešić and

Joško Mitrović

submission deadline 20 Nov 2025 | 1 articles | Viewed by 833 | Submission Open

Keywords: rheumatoid arthritis; pulmonary manifestations of rheumatoid arthritis; cardiovascular manifestations of rheumatoid arthritis; rheumatoid arthritis and osteoporosis; anemia and rheumatoid arthritis; Felty syndrome; depression and rheumatoid arthritis; amyloidosis and rheumatoid arthritis; rheumatoid arthritis and malignancies; rheumatoid arthritis and pregnancy

(This special issue belongs to the Section Hematology and Immunology)

New Trends in Chronic Obstructive Pulmonary Disease (COPD)

edited by Alberto Fantin and

Ernesto Crisafulli

submission deadline 20 Nov 2025 | 1 articles | Viewed by 692 | Submission Open

Keywords: COPD management; pulmonary rehabilitation; airflow limitation; respiratory symptoms; disease monitoring; non-pharmacological treatments; precision medicine; environmental factors; exacerbation prevention; patient-centered care

(This special issue belongs to the Section Pulmonology)

Adenomyosis and Endometriosis-Related Infertility

edited by

Simone Ferrero

and

Giuseppe Gullo

submission deadline 20 Nov 2025 | Viewed by 228 | Submission Open

Keywords: endometriosis; adenomyosis; infertility; in vitro fertilization; surgery; laparoscopy

(This special issue belongs to the Section Obstetrics and Gynecology)

Dermato-Engineering and AI Assessment in Dermatology Practice

edited by

Emmanouil Karampinis

and

Paweł Pietkiewicz

submission deadline 20 Nov 2025 | Viewed by 178 | Submission Open

Keywords: artificial intelligence; skin cancer detection; AI-augmented tools; chatbots; AI-powered follow-up; patient’ s attitude to AI use

(This special issue belongs to the Section Dermatology)

Prevention and Treatment of Myopia in Children

edited by Ivana Mravičić and Maja Bohač

submission deadline 20 Nov 2025 | Viewed by 160 | Submission Open

Keywords: myopia control in children; myopia control glasses; Atropine for myopia treatment; DIMS glasses; HALT glasses

(This special issue belongs to the Section Ophthalmology)

New Insights into the Diagnosis, Management, and Interventions of Mood Disorders

edited by Ioana Valentina Micluţia and

Cristian Delcea

submission deadline 25 Nov 2025 | 3 articles | Viewed by 5583 | Submission Open

Keywords: mood disorders; anxiety; depression; psychotherapy; pharmacological treatments; cognitive behavioral therapy; dialectical behavioral therapy; emotional dysregulation

(This special issue belongs to the Section Psychiatry)

Diagnostic Imaging in the Theranostic Era: From ¹³¹I Scintigraphy to the Latest Innovations

edited by Francesco Bertagna and

Pietro Bellini

submission deadline 25 Nov 2025 | 1 articles | Viewed by 688 | Submission Open

Keywords: theranostic; nuclear medicine therapy; thyroid cancer; DTC; neuroendocrine tumor; PET; PRRT; prostate cancer; radiotracers; dosimetry; narrative review; systematic review; comprehensive review; radioiodine

(This special issue belongs to the Section Oncology)

Thermology Health Care Applications and Medical Thermography

edited by

Marcos Leal Brioschi

submission deadline 30 Nov 2025 | 1 articles | Viewed by 13622 | Submission Open

Keywords: public health; medical termography; pain; breast cancer; cardiovascular disease; surgery; artificial intelligence; HealthTech; diabetes

Updates on Risk Factors, Prevention and Treatment of Knee Disease

edited by

Giuseppe Solarino

Giuseppe Maccagnano

and

Michele Coviello

submission deadline 30 Nov 2025 | 3 articles | Viewed by 5573 | Submission Open

Keywords: sports medicine; trauma; degenerative; regenerative; rehabilitation; prevention

(This special issue belongs to the Section Orthopedics)

Stroke: Diagnostic Approaches and Therapies: 2nd Edition

edited by

Anna Podlasek

and Iris Quasar Grunwald

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4349 | Submission Open

Keywords: stroke; thrombolysis; tenecteplase; mechanical thrombectomy; neuroprotection; neuroimaging

(This special issue belongs to the Section Neurology)

Quality of Life Assessment in Oncology Patients

edited by

Raluca Maria Pop

and Claudia Florentina Militaru

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4158 | Submission Open

Keywords: quality of life; oncology patients; individual needs; clinical decisions

(This special issue belongs to the Section Oncology)

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